Machine learning modeling for solubility prediction of recombinant antibody fragment in four different E. coli strains
Abstract The solubility of proteins is usually a necessity for their functioning. Recently an emergence of machine learning approaches as trained alternatives to statistical models has been evidenced for empirical modeling and optimization. Here, soluble production of anti-EpCAM extracellular domain...
| Autors principals: | , , |
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| Format: | Article |
| Idioma: | English |
| Publicat: |
Nature Portfolio
2022-03-01
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| Col·lecció: | Scientific Reports |
| Accés en línia: | https://doi.org/10.1038/s41598-022-09500-6 |