Family and personal history of cancer in the All of Us research program for precision medicine.
The All of Us (AoU) Research Program is making available one of the largest and most diverse collections of health data in the US to researchers. Using the All of Us database, we evaluated family and personal histories of five common types of cancer in 89,453 individuals, comparing these data to 24,...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2023-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0288496&type=printable |
| _version_ | 1797292820857356288 |
|---|---|
| author | Lauryn Keeler Bruce Paulina Paul Katherine K Kim Jihoon Kim Theresa H M Keegan Robert A Hiatt Lucila Ohno-Machado All of Us Research Program Investigators |
| author_facet | Lauryn Keeler Bruce Paulina Paul Katherine K Kim Jihoon Kim Theresa H M Keegan Robert A Hiatt Lucila Ohno-Machado All of Us Research Program Investigators |
| author_sort | Lauryn Keeler Bruce |
| collection | DOAJ |
| description | The All of Us (AoU) Research Program is making available one of the largest and most diverse collections of health data in the US to researchers. Using the All of Us database, we evaluated family and personal histories of five common types of cancer in 89,453 individuals, comparing these data to 24,305 participants from the 2015 National Health Interview Survey (NHIS). Comparing datasets, we found similar family cancer history (33%) rates, but higher personal cancer history in the AoU dataset (9.2% in AoU vs. 5.11% in NHIS), Methodological (e.g. survey-versus telephone-based data collection) and demographic variability may explain these between-data differences, but more research is needed. |
| first_indexed | 2024-03-07T20:03:04Z |
| format | Article |
| id | doaj.art-5be321dc4b7f47c18f910805f0665e35 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-03-07T20:03:04Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-5be321dc4b7f47c18f910805f0665e352024-02-28T05:31:48ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01187e028849610.1371/journal.pone.0288496Family and personal history of cancer in the All of Us research program for precision medicine.Lauryn Keeler BrucePaulina PaulKatherine K KimJihoon KimTheresa H M KeeganRobert A HiattLucila Ohno-MachadoAll of Us Research Program InvestigatorsThe All of Us (AoU) Research Program is making available one of the largest and most diverse collections of health data in the US to researchers. Using the All of Us database, we evaluated family and personal histories of five common types of cancer in 89,453 individuals, comparing these data to 24,305 participants from the 2015 National Health Interview Survey (NHIS). Comparing datasets, we found similar family cancer history (33%) rates, but higher personal cancer history in the AoU dataset (9.2% in AoU vs. 5.11% in NHIS), Methodological (e.g. survey-versus telephone-based data collection) and demographic variability may explain these between-data differences, but more research is needed.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0288496&type=printable |
| spellingShingle | Lauryn Keeler Bruce Paulina Paul Katherine K Kim Jihoon Kim Theresa H M Keegan Robert A Hiatt Lucila Ohno-Machado All of Us Research Program Investigators Family and personal history of cancer in the All of Us research program for precision medicine. PLoS ONE |
| title | Family and personal history of cancer in the All of Us research program for precision medicine. |
| title_full | Family and personal history of cancer in the All of Us research program for precision medicine. |
| title_fullStr | Family and personal history of cancer in the All of Us research program for precision medicine. |
| title_full_unstemmed | Family and personal history of cancer in the All of Us research program for precision medicine. |
| title_short | Family and personal history of cancer in the All of Us research program for precision medicine. |
| title_sort | family and personal history of cancer in the all of us research program for precision medicine |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0288496&type=printable |
| work_keys_str_mv | AT laurynkeelerbruce familyandpersonalhistoryofcancerintheallofusresearchprogramforprecisionmedicine AT paulinapaul familyandpersonalhistoryofcancerintheallofusresearchprogramforprecisionmedicine AT katherinekkim familyandpersonalhistoryofcancerintheallofusresearchprogramforprecisionmedicine AT jihoonkim familyandpersonalhistoryofcancerintheallofusresearchprogramforprecisionmedicine AT theresahmkeegan familyandpersonalhistoryofcancerintheallofusresearchprogramforprecisionmedicine AT robertahiatt familyandpersonalhistoryofcancerintheallofusresearchprogramforprecisionmedicine AT lucilaohnomachado familyandpersonalhistoryofcancerintheallofusresearchprogramforprecisionmedicine AT allofusresearchprograminvestigators familyandpersonalhistoryofcancerintheallofusresearchprogramforprecisionmedicine |