Sterol-regulated transmembrane protein TMEM86a couples LXR signaling to regulation of lysoplasmalogens in macrophages

Sterol-regulated transmembrane protein TMEM86a couples LXR signaling to regulation of lysoplasmalogens in macrophages

Lysoplasmalogens are a class of vinyl ether bioactive lipids that have a central role in plasmalogen metabolism and membrane fluidity. The liver X receptor (LXR) transcription factors are important determinants of cellular lipid homeostasis owing to their ability to regulate cholesterol and fatty ac...

Full description

Bibliographic Details
Main Authors: Suzanne A.E. van Wouw, Marlene van den Berg, Maroua El Ouraoui, Amber Meurs, Jenina Kingma, Roelof Ottenhoff, Melanie Loix, Marten A. Hoeksema, Koen Prange, Gerard Pasterkamp, Jerome J.A. Hendriks, Jeroen F.J. Bogie, Jan B. van Klinken, Frederic M. Vaz, Aldo Jongejan, Menno P.J. de Winther, Noam Zelcer
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Journal of Lipid Research
Subjects:
bone marrow–derived macrophages
plasmalogens
lysoplasmalogens
LXR
lipid metabolism
lipidomics
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227522001584

Internet

http://www.sciencedirect.com/science/article/pii/S0022227522001584

Similar Items