Inter-Rater Reliability between Structured and Non-Structured Interviews Is Fair in Schizophrenia and Bipolar Disorders—A Systematic Review and Meta-Analysis

We aimed to find agreement between diagnoses obtained through standardized (SDI) and non-standardized diagnostic interviews (NSDI) for schizophrenia and Bipolar Affective Disorder (BD). Methods: A systematic review with meta-analysis was conducted. Publications from 2007 to 2020 comparing SDI and NS...

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Main Authors: Hélio Rocha Neto, Ana Lúcia R. Moreira, Lucas Hosken, Joshua A. Langfus, Maria Tavares Cavalcanti, Eric Arden Youngstrom, Diogo Telles-Correia
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/13/3/526
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author Hélio Rocha Neto
Ana Lúcia R. Moreira
Lucas Hosken
Joshua A. Langfus
Maria Tavares Cavalcanti
Eric Arden Youngstrom
Diogo Telles-Correia
author_facet Hélio Rocha Neto
Ana Lúcia R. Moreira
Lucas Hosken
Joshua A. Langfus
Maria Tavares Cavalcanti
Eric Arden Youngstrom
Diogo Telles-Correia
author_sort Hélio Rocha Neto
collection DOAJ
description We aimed to find agreement between diagnoses obtained through standardized (SDI) and non-standardized diagnostic interviews (NSDI) for schizophrenia and Bipolar Affective Disorder (BD). Methods: A systematic review with meta-analysis was conducted. Publications from 2007 to 2020 comparing SDI and NSDI diagnoses in adults without neurological disorders were screened in MEDLINE, ISI Web of Science, and SCOPUS, following PROSPERO registration CRD42020187157, PRISMA guidelines, and quality assessment using QUADAS–2. Results: From 54231 entries, 22 studies were analyzed, and 13 were included in the final meta-analysis of kappa agreement using a mixed-effects meta-regression model. A mean kappa of 0.41 (Fair agreement, 95% CI: 0.34 to 0.47) but high heterogeneity (<i>Î</i><sup>2</sup> = 92%) were calculated. Gender, mean age, NSDI setting (Inpatient vs. Outpatient; University vs. Non-university), and SDI informant (Self vs. Professional) were tested as predictors in meta-regression. Only SDI informant was relevant for the explanatory model, leaving 79% unexplained heterogeneity. Egger’s test did not indicate significant bias, and QUADAS–2 resulted in “average” data quality. Conclusions: Most studies using SDIs do not report the original sample size, only the SDI-diagnosed patients. Kappa comparison resulted in high heterogeneity, which may reflect the influence of non-systematic bias in diagnostic processes. Although results were highly heterogeneous, we measured a fair agreement kappa between SDI and NSDI, implying clinicians might operate in scenarios not equivalent to psychiatry trials, where samples are filtered, and there may be more emphasis on maintaining reliability. The present study received no funding.
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spelling doaj.art-5be6f831650249c3a96ee94722ce86a82023-11-16T16:26:04ZengMDPI AGDiagnostics2075-44182023-01-0113352610.3390/diagnostics13030526Inter-Rater Reliability between Structured and Non-Structured Interviews Is Fair in Schizophrenia and Bipolar Disorders—A Systematic Review and Meta-AnalysisHélio Rocha Neto0Ana Lúcia R. Moreira1Lucas Hosken2Joshua A. Langfus3Maria Tavares Cavalcanti4Eric Arden Youngstrom5Diogo Telles-Correia6Medical Faculty, Lisbon University, 1649-028 Lisbon, PortugalCork Kerry Community Healthcare, T12YE02 Cork, IrelandMedical Psychology Sector, University Hospital Clementino Fraga Filho, HUCFF/UFRJ, Rio de Janeiro 21941913, RJ, BrazilClinical Psychology Program, Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3270, USAPrograma de Pós Graduação em Psiquiatria e Saúde Mental—PROPSAM, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro—UFRJ, Rio de Janeiro 22290140, RJ, BrazilClinical Psychology Program, Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3270, USAMedical Faculty, Lisbon University, 1649-028 Lisbon, PortugalWe aimed to find agreement between diagnoses obtained through standardized (SDI) and non-standardized diagnostic interviews (NSDI) for schizophrenia and Bipolar Affective Disorder (BD). Methods: A systematic review with meta-analysis was conducted. Publications from 2007 to 2020 comparing SDI and NSDI diagnoses in adults without neurological disorders were screened in MEDLINE, ISI Web of Science, and SCOPUS, following PROSPERO registration CRD42020187157, PRISMA guidelines, and quality assessment using QUADAS–2. Results: From 54231 entries, 22 studies were analyzed, and 13 were included in the final meta-analysis of kappa agreement using a mixed-effects meta-regression model. A mean kappa of 0.41 (Fair agreement, 95% CI: 0.34 to 0.47) but high heterogeneity (<i>Î</i><sup>2</sup> = 92%) were calculated. Gender, mean age, NSDI setting (Inpatient vs. Outpatient; University vs. Non-university), and SDI informant (Self vs. Professional) were tested as predictors in meta-regression. Only SDI informant was relevant for the explanatory model, leaving 79% unexplained heterogeneity. Egger’s test did not indicate significant bias, and QUADAS–2 resulted in “average” data quality. Conclusions: Most studies using SDIs do not report the original sample size, only the SDI-diagnosed patients. Kappa comparison resulted in high heterogeneity, which may reflect the influence of non-systematic bias in diagnostic processes. Although results were highly heterogeneous, we measured a fair agreement kappa between SDI and NSDI, implying clinicians might operate in scenarios not equivalent to psychiatry trials, where samples are filtered, and there may be more emphasis on maintaining reliability. The present study received no funding.https://www.mdpi.com/2075-4418/13/3/526standard diagnostic interviewmeta-analysisschizophreniabipolar affective disorderreliability and validity
spellingShingle Hélio Rocha Neto
Ana Lúcia R. Moreira
Lucas Hosken
Joshua A. Langfus
Maria Tavares Cavalcanti
Eric Arden Youngstrom
Diogo Telles-Correia
Inter-Rater Reliability between Structured and Non-Structured Interviews Is Fair in Schizophrenia and Bipolar Disorders—A Systematic Review and Meta-Analysis
Diagnostics
standard diagnostic interview
meta-analysis
schizophrenia
bipolar affective disorder
reliability and validity
title Inter-Rater Reliability between Structured and Non-Structured Interviews Is Fair in Schizophrenia and Bipolar Disorders—A Systematic Review and Meta-Analysis
title_full Inter-Rater Reliability between Structured and Non-Structured Interviews Is Fair in Schizophrenia and Bipolar Disorders—A Systematic Review and Meta-Analysis
title_fullStr Inter-Rater Reliability between Structured and Non-Structured Interviews Is Fair in Schizophrenia and Bipolar Disorders—A Systematic Review and Meta-Analysis
title_full_unstemmed Inter-Rater Reliability between Structured and Non-Structured Interviews Is Fair in Schizophrenia and Bipolar Disorders—A Systematic Review and Meta-Analysis
title_short Inter-Rater Reliability between Structured and Non-Structured Interviews Is Fair in Schizophrenia and Bipolar Disorders—A Systematic Review and Meta-Analysis
title_sort inter rater reliability between structured and non structured interviews is fair in schizophrenia and bipolar disorders a systematic review and meta analysis
topic standard diagnostic interview
meta-analysis
schizophrenia
bipolar affective disorder
reliability and validity
url https://www.mdpi.com/2075-4418/13/3/526
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