Antenatal Corticosteroids and Respiratory Distresses Outcome in Preterm Neonates
Background: The value of antenatal corticosteroid regimen in lessening respiratory distress risk in preterm neonates has been well known, and accordingly, antenatal corticosteroid therapy was recommended for any pregnant woman likely to deliver between 24 and 34 weeks of gestation. Therefore, this s...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2021-04-01
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| Series: | Iranian Journal of Neonatology |
| Subjects: | |
| Online Access: | https://ijn.mums.ac.ir/article_17383_350bb7e5b87fc0922c4dbf6ccb086c97.pdf |
| _version_ | 1818356468758347776 |
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| author | Fatma Mohamed Badr El Din Mesbah Abdelmoneim Khashana |
| author_facet | Fatma Mohamed Badr El Din Mesbah Abdelmoneim Khashana |
| author_sort | Fatma Mohamed |
| collection | DOAJ |
| description | Background: The value of antenatal corticosteroid regimen in lessening respiratory distress risk in preterm neonates has been well known, and accordingly, antenatal corticosteroid therapy was recommended for any pregnant woman likely to deliver between 24 and 34 weeks of gestation. Therefore, this study aimed to assess the association between the administration of antenatal corticosteroids within the ideal interval of one week before birth and the outcomes of preterm neonates.
Methods: This prospective cohort study included 80 preterm neonates admitted to the neonatal intensive care unit with gestational age from 32 to 37 complete weeks at Suez Canal University Hospitals, Ismailia, Egypt. The newborns were then divided into groups A (did not receive antenatal corticosteroids; n=40) and B (received antenatal corticosteroids; n=40).
Results: Severe respiratory distress syndrome was significantly less frequent in group B (P<0.05) with lower levels of need for oxygen supplementation (P<0.05).
Conclusion: Neonates who received antenatal corticosteroids developed less severe respiratory distress, compared to neonates who did not receive this medication. The results favored the use of antenatal corticosteroids to prevent respiratory distress when administrated within the ideal interval of one week before birth. |
| first_indexed | 2024-12-13T19:57:42Z |
| format | Article |
| id | doaj.art-5bed0a0d725e45efb56b2376f2d9a61b |
| institution | Directory Open Access Journal |
| issn | 2251-7510 2322-2158 |
| language | English |
| last_indexed | 2024-12-13T19:57:42Z |
| publishDate | 2021-04-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Neonatology |
| spelling | doaj.art-5bed0a0d725e45efb56b2376f2d9a61b2022-12-21T23:33:16ZengMashhad University of Medical SciencesIranian Journal of Neonatology2251-75102322-21582021-04-01122404510.22038/ijn.2021.49556.186517383Antenatal Corticosteroids and Respiratory Distresses Outcome in Preterm NeonatesFatma Mohamed0Badr El Din Mesbah1Abdelmoneim Khashana2Bir El Abd Hospital, North Sini, EgyptFaculty of Medicine, Suez Canal University, Ismailia, EgyptFaculty of Medicine, Suez Canal University, Ismailia, EgyptBackground: The value of antenatal corticosteroid regimen in lessening respiratory distress risk in preterm neonates has been well known, and accordingly, antenatal corticosteroid therapy was recommended for any pregnant woman likely to deliver between 24 and 34 weeks of gestation. Therefore, this study aimed to assess the association between the administration of antenatal corticosteroids within the ideal interval of one week before birth and the outcomes of preterm neonates. Methods: This prospective cohort study included 80 preterm neonates admitted to the neonatal intensive care unit with gestational age from 32 to 37 complete weeks at Suez Canal University Hospitals, Ismailia, Egypt. The newborns were then divided into groups A (did not receive antenatal corticosteroids; n=40) and B (received antenatal corticosteroids; n=40). Results: Severe respiratory distress syndrome was significantly less frequent in group B (P<0.05) with lower levels of need for oxygen supplementation (P<0.05). Conclusion: Neonates who received antenatal corticosteroids developed less severe respiratory distress, compared to neonates who did not receive this medication. The results favored the use of antenatal corticosteroids to prevent respiratory distress when administrated within the ideal interval of one week before birth.https://ijn.mums.ac.ir/article_17383_350bb7e5b87fc0922c4dbf6ccb086c97.pdfantenatalcorticosteroidspretermrespiratory distress syndrome (rds) |
| spellingShingle | Fatma Mohamed Badr El Din Mesbah Abdelmoneim Khashana Antenatal Corticosteroids and Respiratory Distresses Outcome in Preterm Neonates Iranian Journal of Neonatology antenatal corticosteroids preterm respiratory distress syndrome (rds) |
| title | Antenatal Corticosteroids and Respiratory Distresses Outcome in Preterm Neonates |
| title_full | Antenatal Corticosteroids and Respiratory Distresses Outcome in Preterm Neonates |
| title_fullStr | Antenatal Corticosteroids and Respiratory Distresses Outcome in Preterm Neonates |
| title_full_unstemmed | Antenatal Corticosteroids and Respiratory Distresses Outcome in Preterm Neonates |
| title_short | Antenatal Corticosteroids and Respiratory Distresses Outcome in Preterm Neonates |
| title_sort | antenatal corticosteroids and respiratory distresses outcome in preterm neonates |
| topic | antenatal corticosteroids preterm respiratory distress syndrome (rds) |
| url | https://ijn.mums.ac.ir/article_17383_350bb7e5b87fc0922c4dbf6ccb086c97.pdf |
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