Comparative Analysis of Two Automated Fat-processing Systems
Background:. Plastic surgeons desire more efficient methods of processing lipoaspirate when performing fat grafting procedures. We compared, in a preclinical study, the quantity and quality of lipoaspirate processed by a novel Poloxamer Wash, Absorption, mesh filtration System (PWAS) to a frequently...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer
2020-01-01
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| Series: | Plastic and Reconstructive Surgery, Global Open |
| Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002587 |
| _version_ | 1818131908937121792 |
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| author | Yang An, MD, PhD Adriana C. Panayi, MD Bobin Mi, MD Siqi Fu, MD, PhD Dennis P. Orgill, MD, PhD |
| author_facet | Yang An, MD, PhD Adriana C. Panayi, MD Bobin Mi, MD Siqi Fu, MD, PhD Dennis P. Orgill, MD, PhD |
| author_sort | Yang An, MD, PhD |
| collection | DOAJ |
| description | Background:. Plastic surgeons desire more efficient methods of processing lipoaspirate when performing fat grafting procedures. We compared, in a preclinical study, the quantity and quality of lipoaspirate processed by a novel Poloxamer Wash, Absorption, mesh filtration System (PWAS) to a frequently used Ringer’s Lactate wash, Decant, and mesh filtration System (RLDS).
Methods:. Lipoaspirate from 10 patients was processed with the RLDS and PWAS systems. The processed lipoaspirate from each device was centrifuged to quantify the amount of fat, free oil, and aqueous components remaining in the fat graft. A trypan blue dye exclusion test assessed cell viability. The processing time for the lipoaspirate was also measured.
Results:. The 10-patient average fat volume processed and available for grafting was similar using both systems. The adipose volume fraction of PWAS was greater (89% ± 3%) than RLDS (76% ± 10%, P = 0.02). The trypan blue exclusion values and processing time were similar for both systems. Oil was efficiently removed from the lipoaspirate, and both systems processed fat efficiently.
Conclusion:. The PWAS effectively cleans lipoaspirate with increased fat concentration. |
| first_indexed | 2024-12-11T08:28:25Z |
| format | Article |
| id | doaj.art-5bedaf50fddb4e3ba573c29ea49de0dd |
| institution | Directory Open Access Journal |
| issn | 2169-7574 |
| language | English |
| last_indexed | 2024-12-11T08:28:25Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Plastic and Reconstructive Surgery, Global Open |
| spelling | doaj.art-5bedaf50fddb4e3ba573c29ea49de0dd2022-12-22T01:14:30ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742020-01-0181e258710.1097/GOX.0000000000002587202001000-00015Comparative Analysis of Two Automated Fat-processing SystemsYang An, MD, PhD0Adriana C. Panayi, MD1Bobin Mi, MD2Siqi Fu, MD, PhD3Dennis P. Orgill, MD, PhD4From the * Division of Plastic Surgery, Department of Surgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass.From the * Division of Plastic Surgery, Department of Surgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass.From the * Division of Plastic Surgery, Department of Surgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass.From the * Division of Plastic Surgery, Department of Surgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass.From the * Division of Plastic Surgery, Department of Surgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass.Background:. Plastic surgeons desire more efficient methods of processing lipoaspirate when performing fat grafting procedures. We compared, in a preclinical study, the quantity and quality of lipoaspirate processed by a novel Poloxamer Wash, Absorption, mesh filtration System (PWAS) to a frequently used Ringer’s Lactate wash, Decant, and mesh filtration System (RLDS). Methods:. Lipoaspirate from 10 patients was processed with the RLDS and PWAS systems. The processed lipoaspirate from each device was centrifuged to quantify the amount of fat, free oil, and aqueous components remaining in the fat graft. A trypan blue dye exclusion test assessed cell viability. The processing time for the lipoaspirate was also measured. Results:. The 10-patient average fat volume processed and available for grafting was similar using both systems. The adipose volume fraction of PWAS was greater (89% ± 3%) than RLDS (76% ± 10%, P = 0.02). The trypan blue exclusion values and processing time were similar for both systems. Oil was efficiently removed from the lipoaspirate, and both systems processed fat efficiently. Conclusion:. The PWAS effectively cleans lipoaspirate with increased fat concentration.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002587 |
| spellingShingle | Yang An, MD, PhD Adriana C. Panayi, MD Bobin Mi, MD Siqi Fu, MD, PhD Dennis P. Orgill, MD, PhD Comparative Analysis of Two Automated Fat-processing Systems Plastic and Reconstructive Surgery, Global Open |
| title | Comparative Analysis of Two Automated Fat-processing Systems |
| title_full | Comparative Analysis of Two Automated Fat-processing Systems |
| title_fullStr | Comparative Analysis of Two Automated Fat-processing Systems |
| title_full_unstemmed | Comparative Analysis of Two Automated Fat-processing Systems |
| title_short | Comparative Analysis of Two Automated Fat-processing Systems |
| title_sort | comparative analysis of two automated fat processing systems |
| url | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002587 |
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