Comparing prevalence and types of potentially inappropriate medications among patient groups in a post-acute and secondary care hospital

Abstract Reducing potentially inappropriate medications (PIMs) is a challenge in post-acute care hospitals. Some PIMs may be associated with patient characteristics and it may be useful to focus on frequent PIMs. This study aimed to identify characteristic features of PIMs by grouping patients as in...

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Main Authors: Hirotaka Nakashima, Hiromichi Ando, Hiroyuki Umegaki
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41617-0
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author Hirotaka Nakashima
Hiromichi Ando
Hiroyuki Umegaki
author_facet Hirotaka Nakashima
Hiromichi Ando
Hiroyuki Umegaki
author_sort Hirotaka Nakashima
collection DOAJ
description Abstract Reducing potentially inappropriate medications (PIMs) is a challenge in post-acute care hospitals. Some PIMs may be associated with patient characteristics and it may be useful to focus on frequent PIMs. This study aimed to identify characteristic features of PIMs by grouping patients as in everyday clinical practice. A retrospective review of medical records was conducted for 541 patients aged 75 years or older in a Japanese post-acute and secondary care hospital. PIMs on admission were identified using the Screening Tool for Older Person’s Appropriate Prescriptions for Japanese. The patients were divided into four groups based on their primary disease and reason for hospitalization: post-acute orthopedics, post-acute neurological disorders, post-acute others, and subacute. Approximately 60.8% of the patients were taking PIMs, with no significant difference among the four patient groups in terms of prevalence of PIMs (p = 0.08). However, characteristic features of PIM types were observed in each patient group. Hypnotics and nonsteroidal anti-inflammatory drugs were common in the post-acute orthopedics group, multiple antithrombotic agents in the post-acute neurological disorders group, diuretics in the post-acute others group, and hypnotics and diuretics in the subacute group. Grouping patients in clinical practice revealed characteristic features of PIM types in each group.
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spelling doaj.art-5beea9dbadb141d380c4a07337a3385c2023-11-20T09:24:13ZengNature PortfolioScientific Reports2045-23222023-09-0113111010.1038/s41598-023-41617-0Comparing prevalence and types of potentially inappropriate medications among patient groups in a post-acute and secondary care hospitalHirotaka Nakashima0Hiromichi Ando1Hiroyuki Umegaki2Department of Community Healthcare and Geriatrics, Nagoya University Graduate School of MedicineWako-Kai Yamada HospitalDepartment of Community Healthcare and Geriatrics, Nagoya University Graduate School of MedicineAbstract Reducing potentially inappropriate medications (PIMs) is a challenge in post-acute care hospitals. Some PIMs may be associated with patient characteristics and it may be useful to focus on frequent PIMs. This study aimed to identify characteristic features of PIMs by grouping patients as in everyday clinical practice. A retrospective review of medical records was conducted for 541 patients aged 75 years or older in a Japanese post-acute and secondary care hospital. PIMs on admission were identified using the Screening Tool for Older Person’s Appropriate Prescriptions for Japanese. The patients were divided into four groups based on their primary disease and reason for hospitalization: post-acute orthopedics, post-acute neurological disorders, post-acute others, and subacute. Approximately 60.8% of the patients were taking PIMs, with no significant difference among the four patient groups in terms of prevalence of PIMs (p = 0.08). However, characteristic features of PIM types were observed in each patient group. Hypnotics and nonsteroidal anti-inflammatory drugs were common in the post-acute orthopedics group, multiple antithrombotic agents in the post-acute neurological disorders group, diuretics in the post-acute others group, and hypnotics and diuretics in the subacute group. Grouping patients in clinical practice revealed characteristic features of PIM types in each group.https://doi.org/10.1038/s41598-023-41617-0
spellingShingle Hirotaka Nakashima
Hiromichi Ando
Hiroyuki Umegaki
Comparing prevalence and types of potentially inappropriate medications among patient groups in a post-acute and secondary care hospital
Scientific Reports
title Comparing prevalence and types of potentially inappropriate medications among patient groups in a post-acute and secondary care hospital
title_full Comparing prevalence and types of potentially inappropriate medications among patient groups in a post-acute and secondary care hospital
title_fullStr Comparing prevalence and types of potentially inappropriate medications among patient groups in a post-acute and secondary care hospital
title_full_unstemmed Comparing prevalence and types of potentially inappropriate medications among patient groups in a post-acute and secondary care hospital
title_short Comparing prevalence and types of potentially inappropriate medications among patient groups in a post-acute and secondary care hospital
title_sort comparing prevalence and types of potentially inappropriate medications among patient groups in a post acute and secondary care hospital
url https://doi.org/10.1038/s41598-023-41617-0
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