IgA Deficiency in Blood Donors in Zahedan, Iran
Background and Objectives: Anaphylactic reaction is one of the most important transfusion anaphylactic reactions in medicine. During transfusion if Individuals with IgA deficiency take blood which containing IgA, they would suffer from severe allergic reaction. Since there is a little known about th...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | fas |
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Tehran University of Medical Sciences
2009-09-01
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| Series: | مجله اپیدمیولوژی ایران |
| Subjects: | |
| Online Access: | http://irje.tums.ac.ir/browse.php?a_code=A-10-25-118&slc_lang=en&sid=1 |
| _version_ | 1818388841677979648 |
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| author | R Nosratabadi E Saneimoghadam M Arababadi S Khosravi Gh Hassanshahi R Vazirinegad |
| author_facet | R Nosratabadi E Saneimoghadam M Arababadi S Khosravi Gh Hassanshahi R Vazirinegad |
| author_sort | R Nosratabadi |
| collection | DOAJ |
| description | Background and Objectives: Anaphylactic reaction is one of the most important transfusion anaphylactic reactions in medicine. During transfusion if Individuals with IgA deficiency take blood which containing IgA, they would suffer from severe allergic reaction. Since there is a little known about this in different ethnic groups in Iran we have decided to evaluate this issue in Sistan & Baluchestan province in Iran.
Methods: During one year, blood samples were collected from 3837 volunteer blood donors. Then the serum samples were tested for IgA titer by nephlometry and SRID techniques.
Results: According to our results only, one donor (0.026%) was found to have IgA less than 5mg/dl and 34(0.9%) cases had IgA: 5-30 mg/dl while 3798(99%) had IgA more than 30mg/dl.
Conclusions: With regards to very low prevalence of IgA deficiency in blood donors in Southeast part of Iran, it seems that anaphylactic reactions most likely be due to other factors in the individuals that receive blood products. |
| first_indexed | 2024-12-14T04:32:15Z |
| format | Article |
| id | doaj.art-5bfe4ce008b24b6d8fece8f36caf782c |
| institution | Directory Open Access Journal |
| issn | 1735-7489 2228-7507 |
| language | fas |
| last_indexed | 2024-12-14T04:32:15Z |
| publishDate | 2009-09-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | مجله اپیدمیولوژی ایران |
| spelling | doaj.art-5bfe4ce008b24b6d8fece8f36caf782c2022-12-21T23:17:03ZfasTehran University of Medical Sciencesمجله اپیدمیولوژی ایران1735-74892228-75072009-09-01525557IgA Deficiency in Blood Donors in Zahedan, IranR Nosratabadi 0E Saneimoghadam 1 M Arababadi2S Khosravi 3Gh Hassanshahi 4R Vazirinegad 5 Background and Objectives: Anaphylactic reaction is one of the most important transfusion anaphylactic reactions in medicine. During transfusion if Individuals with IgA deficiency take blood which containing IgA, they would suffer from severe allergic reaction. Since there is a little known about this in different ethnic groups in Iran we have decided to evaluate this issue in Sistan & Baluchestan province in Iran. Methods: During one year, blood samples were collected from 3837 volunteer blood donors. Then the serum samples were tested for IgA titer by nephlometry and SRID techniques. Results: According to our results only, one donor (0.026%) was found to have IgA less than 5mg/dl and 34(0.9%) cases had IgA: 5-30 mg/dl while 3798(99%) had IgA more than 30mg/dl. Conclusions: With regards to very low prevalence of IgA deficiency in blood donors in Southeast part of Iran, it seems that anaphylactic reactions most likely be due to other factors in the individuals that receive blood products.http://irje.tums.ac.ir/browse.php?a_code=A-10-25-118&slc_lang=en&sid=1Blood transfusion ، IgA deficiency ، Anaphylaxy |
| spellingShingle | R Nosratabadi E Saneimoghadam M Arababadi S Khosravi Gh Hassanshahi R Vazirinegad IgA Deficiency in Blood Donors in Zahedan, Iran مجله اپیدمیولوژی ایران Blood transfusion ، IgA deficiency ، Anaphylaxy |
| title | IgA Deficiency in Blood Donors in Zahedan, Iran |
| title_full | IgA Deficiency in Blood Donors in Zahedan, Iran |
| title_fullStr | IgA Deficiency in Blood Donors in Zahedan, Iran |
| title_full_unstemmed | IgA Deficiency in Blood Donors in Zahedan, Iran |
| title_short | IgA Deficiency in Blood Donors in Zahedan, Iran |
| title_sort | iga deficiency in blood donors in zahedan iran |
| topic | Blood transfusion ، IgA deficiency ، Anaphylaxy |
| url | http://irje.tums.ac.ir/browse.php?a_code=A-10-25-118&slc_lang=en&sid=1 |
| work_keys_str_mv | AT rnosratabadi igadeficiencyinblooddonorsinzahedaniran AT esaneimoghadam igadeficiencyinblooddonorsinzahedaniran AT marababadi igadeficiencyinblooddonorsinzahedaniran AT skhosravi igadeficiencyinblooddonorsinzahedaniran AT ghhassanshahi igadeficiencyinblooddonorsinzahedaniran AT rvazirinegad igadeficiencyinblooddonorsinzahedaniran |