Perspective of genetics to understand and treat obesity

Obesity is a multifactorial disease common where environmentaland genetic factors are interactive. In the present paper the role ofgenetic factors in the development of obesity are reviewed basedon epidemiological studies, pleiotropic syndromes, monogenic formsand poligenic obesity. The use of genet...

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Main Author: Cíntia Cercato
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2006-03-01
Series:Einstein (São Paulo)
Subjects:
Online Access:http://www.einstein.br/revista/arquivos/PDF/112-14-17.pdf
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author Cíntia Cercato
author_facet Cíntia Cercato
author_sort Cíntia Cercato
collection DOAJ
description Obesity is a multifactorial disease common where environmentaland genetic factors are interactive. In the present paper the role ofgenetic factors in the development of obesity are reviewed basedon epidemiological studies, pleiotropic syndromes, monogenic formsand poligenic obesity. The use of genetics to identify the criticalmolecular components of the control system of human energetichomeostasis may help in the identification of targets and thedevelopment of specific drugs for the treatment of the disease.
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spelling doaj.art-5bff1fbf920f4e9dac85625f68f9f9192022-12-21T19:01:50ZengInstituto Israelita de Ensino e Pesquisa Albert EinsteinEinstein (São Paulo)1679-45082006-03-014S1S14S17Perspective of genetics to understand and treat obesityCíntia CercatoObesity is a multifactorial disease common where environmentaland genetic factors are interactive. In the present paper the role ofgenetic factors in the development of obesity are reviewed basedon epidemiological studies, pleiotropic syndromes, monogenic formsand poligenic obesity. The use of genetics to identify the criticalmolecular components of the control system of human energetichomeostasis may help in the identification of targets and thedevelopment of specific drugs for the treatment of the disease.http://www.einstein.br/revista/arquivos/PDF/112-14-17.pdfObesity/geneticsObesity/therapy
spellingShingle Cíntia Cercato
Perspective of genetics to understand and treat obesity
Einstein (São Paulo)
Obesity/genetics
Obesity/therapy
title Perspective of genetics to understand and treat obesity
title_full Perspective of genetics to understand and treat obesity
title_fullStr Perspective of genetics to understand and treat obesity
title_full_unstemmed Perspective of genetics to understand and treat obesity
title_short Perspective of genetics to understand and treat obesity
title_sort perspective of genetics to understand and treat obesity
topic Obesity/genetics
Obesity/therapy
url http://www.einstein.br/revista/arquivos/PDF/112-14-17.pdf
work_keys_str_mv AT cintiacercato perspectiveofgeneticstounderstandandtreatobesity