Lower Choline and Myo-Inositol in Temporo-Parietal Cortex Is Associated With Apathy in Amnestic MCI

Lower Choline and Myo-Inositol in Temporo-Parietal Cortex Is Associated With Apathy in Amnestic MCI

Apathy is a common symptom in patients with amnestic mild cognitive impairment (aMCI) and is associated with an increased risk of progression to Alzheimer’s disease (AD). The neural substrates underlying apathy in aMCI may involve multiple brain regions, including the anterior cingulate cortex and t...

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Bibliographic Details
Main Authors: Shankar Tumati, Esther M. Opmeer, Jan-Bernard C. Marsman, Sander Martens, Fransje E. Reesink, Peter P. De Deyn, André Aleman
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
apathy
amnestic MCI
temporo-parietal cortex
goal-directed behavior
choline
myo-inositol
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00106/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2018.00106/full

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