A double deletion prevents replication of the pestivirus bovine viral diarrhea virus in the placenta of pregnant heifers

A double deletion prevents replication of the pestivirus bovine viral diarrhea virus in the placenta of pregnant heifers

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In contrast to wild type bovine viral diarhea virus (BVDV) specific double deletion mutants are not able to establish persistent infection upon infection of a pregnant heifer. Our data shows that this finding results from a defect in transfer of the virus from the mother animal to the fetus. Pregnan...

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Bibliographic Details
Main Authors: Jolene Carlson, Robert Kammerer, Jens Peter Teifke, Julia Sehl-Ewert, Christiane Pfarrer, Gregor Meyers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-12-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654156/?tool=EBI

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