COVID-19 and Obesity: Epidemiology, Pathogenesis and Treatment

Xinyu Zhu,1,2,* Liu Yang,1,2,* Kai Huang1,2 1Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China; 2Clinical Center for Human Genomic Research, Union Hospital, Tongji Medical College, Huazh...

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Main Authors: Zhu X, Yang L, Huang K
Format: Article
Language:English
Published: Dove Medical Press 2020-12-01
Series:Diabetes, Metabolic Syndrome and Obesity
Subjects:
Online Access:https://www.dovepress.com/covid-19-and-obesity-epidemiology-pathogenesis-and-treatment-peer-reviewed-article-DMSO
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author Zhu X
Yang L
Huang K
author_facet Zhu X
Yang L
Huang K
author_sort Zhu X
collection DOAJ
description Xinyu Zhu,1,2,* Liu Yang,1,2,* Kai Huang1,2 1Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China; 2Clinical Center for Human Genomic Research, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Kai HuangDepartment of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan, Hubei 430022, People’s Republic of ChinaEmail Husthuang1003@163.comAbstract: The growing prevalence of overweight and obesity has been a worldwide public health issue. During the COVID-19 pandemic, obesity is associated with a higher risk of severity and a worse clinical outcome of SARS-COV-2 infection. This may be because of the chronic low-grade inflammation, impaired immune response and metabolic disorders in obese patients. In this narrative review, we have summarized the association between obesity and COVID-19 and discussed the potential pathogenesis and treatment in these patients. This work may provide practical suggestions on the clinical management of obese COVID-19 patients.Keywords: COVID-19, obesity, SARS-COV-2
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spelling doaj.art-5c07689644e643b38e77c84cbab4f7a12023-02-02T21:42:33ZengDove Medical PressDiabetes, Metabolic Syndrome and Obesity1178-70072020-12-01Volume 134953495960280COVID-19 and Obesity: Epidemiology, Pathogenesis and TreatmentZhu XYang LHuang KXinyu Zhu,1,2,* Liu Yang,1,2,* Kai Huang1,2 1Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China; 2Clinical Center for Human Genomic Research, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Kai HuangDepartment of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan, Hubei 430022, People’s Republic of ChinaEmail Husthuang1003@163.comAbstract: The growing prevalence of overweight and obesity has been a worldwide public health issue. During the COVID-19 pandemic, obesity is associated with a higher risk of severity and a worse clinical outcome of SARS-COV-2 infection. This may be because of the chronic low-grade inflammation, impaired immune response and metabolic disorders in obese patients. In this narrative review, we have summarized the association between obesity and COVID-19 and discussed the potential pathogenesis and treatment in these patients. This work may provide practical suggestions on the clinical management of obese COVID-19 patients.Keywords: COVID-19, obesity, SARS-COV-2https://www.dovepress.com/covid-19-and-obesity-epidemiology-pathogenesis-and-treatment-peer-reviewed-article-DMSOcovid-19obesity,sars-cov-2
spellingShingle Zhu X
Yang L
Huang K
COVID-19 and Obesity: Epidemiology, Pathogenesis and Treatment
Diabetes, Metabolic Syndrome and Obesity
covid-19
obesity,sars-cov-2
title COVID-19 and Obesity: Epidemiology, Pathogenesis and Treatment
title_full COVID-19 and Obesity: Epidemiology, Pathogenesis and Treatment
title_fullStr COVID-19 and Obesity: Epidemiology, Pathogenesis and Treatment
title_full_unstemmed COVID-19 and Obesity: Epidemiology, Pathogenesis and Treatment
title_short COVID-19 and Obesity: Epidemiology, Pathogenesis and Treatment
title_sort covid 19 and obesity epidemiology pathogenesis and treatment
topic covid-19
obesity,sars-cov-2
url https://www.dovepress.com/covid-19-and-obesity-epidemiology-pathogenesis-and-treatment-peer-reviewed-article-DMSO
work_keys_str_mv AT zhux covid19andobesityepidemiologypathogenesisandtreatment
AT yangl covid19andobesityepidemiologypathogenesisandtreatment
AT huangk covid19andobesityepidemiologypathogenesisandtreatment