Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis

The HeartPy Python toolkit for analysis of noisy signals from heart rate measurements is an excellent tool to use in conjunction with novel wearable sensors. Nevertheless, most of the work to date has focused on applying the toolkit to data measured with commercially available sensors. We demonstrat...

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Main Authors: Teodora Vićentić, Milena Rašljić Rafajilović, Stefan D. Ilić, Bojana Koteska, Ana Madevska Bogdanova, Igor A. Pašti, Fedor Lehocki, Marko Spasenović
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/22/17/6326
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author Teodora Vićentić
Milena Rašljić Rafajilović
Stefan D. Ilić
Bojana Koteska
Ana Madevska Bogdanova
Igor A. Pašti
Fedor Lehocki
Marko Spasenović
author_facet Teodora Vićentić
Milena Rašljić Rafajilović
Stefan D. Ilić
Bojana Koteska
Ana Madevska Bogdanova
Igor A. Pašti
Fedor Lehocki
Marko Spasenović
author_sort Teodora Vićentić
collection DOAJ
description The HeartPy Python toolkit for analysis of noisy signals from heart rate measurements is an excellent tool to use in conjunction with novel wearable sensors. Nevertheless, most of the work to date has focused on applying the toolkit to data measured with commercially available sensors. We demonstrate the application of the HeartPy functions to data obtained with a novel graphene-based heartbeat sensor. We produce the sensor by laser-inducing graphene on a flexible polyimide substrate. Both graphene on the polyimide substrate and graphene transferred onto a PDMS substrate show piezoresistive behavior that can be utilized to measure human heartbeat by registering median cubital vein motion during blood pumping. We process electrical resistance data from the graphene sensor using HeartPy and demonstrate extraction of several heartbeat parameters, in agreement with measurements taken with independent reference sensors. We compare the quality of the heartbeat signal from graphene on different substrates, demonstrating that in all cases the device yields results consistent with reference sensors. Our work is a first demonstration of successful application of HeartPy to analysis of data from a sensor in development.
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spelling doaj.art-5c0a0263c39d48b6a8fb835ed9dc41042023-11-23T14:06:37ZengMDPI AGSensors1424-82202022-08-012217632610.3390/s22176326Laser-Induced Graphene for Heartbeat Monitoring with HeartPy AnalysisTeodora Vićentić0Milena Rašljić Rafajilović1Stefan D. Ilić2Bojana Koteska3Ana Madevska Bogdanova4Igor A. Pašti5Fedor Lehocki6Marko Spasenović7Center for Microelectronic Technologies, Institute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, SerbiaCenter for Microelectronic Technologies, Institute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, SerbiaCenter for Microelectronic Technologies, Institute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, SerbiaFaculty of Computer Science and Engineering (FCSE), “Ss. Cyril and Methodius” University, 1000 Skopje, North MacedoniaFaculty of Computer Science and Engineering (FCSE), “Ss. Cyril and Methodius” University, 1000 Skopje, North MacedoniaFaculty of Physical Chemistry, University of Belgrade, 11158 Belgrade, SerbiaFaculty of Informatics and Information Technologies, Slovak University of Technology, 842 16 Bratislava, SlovakiaCenter for Microelectronic Technologies, Institute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, SerbiaThe HeartPy Python toolkit for analysis of noisy signals from heart rate measurements is an excellent tool to use in conjunction with novel wearable sensors. Nevertheless, most of the work to date has focused on applying the toolkit to data measured with commercially available sensors. We demonstrate the application of the HeartPy functions to data obtained with a novel graphene-based heartbeat sensor. We produce the sensor by laser-inducing graphene on a flexible polyimide substrate. Both graphene on the polyimide substrate and graphene transferred onto a PDMS substrate show piezoresistive behavior that can be utilized to measure human heartbeat by registering median cubital vein motion during blood pumping. We process electrical resistance data from the graphene sensor using HeartPy and demonstrate extraction of several heartbeat parameters, in agreement with measurements taken with independent reference sensors. We compare the quality of the heartbeat signal from graphene on different substrates, demonstrating that in all cases the device yields results consistent with reference sensors. Our work is a first demonstration of successful application of HeartPy to analysis of data from a sensor in development.https://www.mdpi.com/1424-8220/22/17/6326bioinformaticsbiomedical electronicsbiomedical materialsbiomedical signal processingbiosensorsmedical information systems
spellingShingle Teodora Vićentić
Milena Rašljić Rafajilović
Stefan D. Ilić
Bojana Koteska
Ana Madevska Bogdanova
Igor A. Pašti
Fedor Lehocki
Marko Spasenović
Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis
Sensors
bioinformatics
biomedical electronics
biomedical materials
biomedical signal processing
biosensors
medical information systems
title Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis
title_full Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis
title_fullStr Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis
title_full_unstemmed Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis
title_short Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis
title_sort laser induced graphene for heartbeat monitoring with heartpy analysis
topic bioinformatics
biomedical electronics
biomedical materials
biomedical signal processing
biosensors
medical information systems
url https://www.mdpi.com/1424-8220/22/17/6326
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AT bojanakoteska laserinducedgrapheneforheartbeatmonitoringwithheartpyanalysis
AT anamadevskabogdanova laserinducedgrapheneforheartbeatmonitoringwithheartpyanalysis
AT igorapasti laserinducedgrapheneforheartbeatmonitoringwithheartpyanalysis
AT fedorlehocki laserinducedgrapheneforheartbeatmonitoringwithheartpyanalysis
AT markospasenovic laserinducedgrapheneforheartbeatmonitoringwithheartpyanalysis