Approach to amiodarone induced thyroid storm: A case report
Thyroid storm is a thyroid emergency with increased risk for mortality due to elevated levels of circulating thyroid hormone. While it can be caused by a variety of etiologies, thyroid storm secondary to amiodarone can be particularly challenging to manage. This paper describes a case of a 65-year-o...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Journal of Clinical and Translational Endocrinology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214624523000175 |
| _version_ | 1827609564559704064 |
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| author | Taylor Freeman Jillian Pattison Salvatore Savona Ralph Augostini Kyle Vankoevering |
| author_facet | Taylor Freeman Jillian Pattison Salvatore Savona Ralph Augostini Kyle Vankoevering |
| author_sort | Taylor Freeman |
| collection | DOAJ |
| description | Thyroid storm is a thyroid emergency with increased risk for mortality due to elevated levels of circulating thyroid hormone. While it can be caused by a variety of etiologies, thyroid storm secondary to amiodarone can be particularly challenging to manage. This paper describes a case of a 65-year-old man who presented from outside hospital with persistent ventricular tachycardia and multiple implantable defibrillator firings from thyroid storm following amiodarone infusion. Despite conventional first-line pharmacotherapy, he developed cardiogenic shock and multi-organ failure requiring therapeutic plasma exchange. Due to continued deterioration, he underwent emergent total thyroidectomy. Following surgery, the patient experienced clinical stabilization and has now made a complete recovery. In this paper, we highlight the complexities in the management of amiodarone induced thyrotoxicosis and offer a treatment algorithm and indications for early, definitive management with thyroidectomy. |
| first_indexed | 2024-03-09T07:34:12Z |
| format | Article |
| id | doaj.art-5c0a1829ea7a42c7bfa6f5f36f4429e5 |
| institution | Directory Open Access Journal |
| issn | 2214-6245 |
| language | English |
| last_indexed | 2024-03-09T07:34:12Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Clinical and Translational Endocrinology Case Reports |
| spelling | doaj.art-5c0a1829ea7a42c7bfa6f5f36f4429e52023-12-03T05:41:42ZengElsevierJournal of Clinical and Translational Endocrinology Case Reports2214-62452023-12-0130100155Approach to amiodarone induced thyroid storm: A case reportTaylor Freeman0Jillian Pattison1Salvatore Savona2Ralph Augostini3Kyle Vankoevering4Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA; Corresponding author. Wexner Medical Center at The Ohio State University, Department of Otolaryngology-Head and Neck Surgery, 915 Olentangy River Road, Rm 4234, Columbus, OH, 43212, USA.Department of Endocrinology, The Ohio State University Wexner Medical Center, Columbus, OH, USADepartment of Cardiology, The Ohio State University Wexner Medical Center, Columbus, OH, USADepartment of Cardiology, The Ohio State University Wexner Medical Center, Columbus, OH, USADepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USAThyroid storm is a thyroid emergency with increased risk for mortality due to elevated levels of circulating thyroid hormone. While it can be caused by a variety of etiologies, thyroid storm secondary to amiodarone can be particularly challenging to manage. This paper describes a case of a 65-year-old man who presented from outside hospital with persistent ventricular tachycardia and multiple implantable defibrillator firings from thyroid storm following amiodarone infusion. Despite conventional first-line pharmacotherapy, he developed cardiogenic shock and multi-organ failure requiring therapeutic plasma exchange. Due to continued deterioration, he underwent emergent total thyroidectomy. Following surgery, the patient experienced clinical stabilization and has now made a complete recovery. In this paper, we highlight the complexities in the management of amiodarone induced thyrotoxicosis and offer a treatment algorithm and indications for early, definitive management with thyroidectomy.http://www.sciencedirect.com/science/article/pii/S2214624523000175AmiodaroneThyroid stormThyrotoxicosisIntensive careThyroidectomy |
| spellingShingle | Taylor Freeman Jillian Pattison Salvatore Savona Ralph Augostini Kyle Vankoevering Approach to amiodarone induced thyroid storm: A case report Journal of Clinical and Translational Endocrinology Case Reports Amiodarone Thyroid storm Thyrotoxicosis Intensive care Thyroidectomy |
| title | Approach to amiodarone induced thyroid storm: A case report |
| title_full | Approach to amiodarone induced thyroid storm: A case report |
| title_fullStr | Approach to amiodarone induced thyroid storm: A case report |
| title_full_unstemmed | Approach to amiodarone induced thyroid storm: A case report |
| title_short | Approach to amiodarone induced thyroid storm: A case report |
| title_sort | approach to amiodarone induced thyroid storm a case report |
| topic | Amiodarone Thyroid storm Thyrotoxicosis Intensive care Thyroidectomy |
| url | http://www.sciencedirect.com/science/article/pii/S2214624523000175 |
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