Endocrine disorders and fertility and pregnancy: An update
It is estimated that more and more couples suffer from fertility and pregnancy maintenance disorders. It is associated with impaired androgen secretion, which is influenced by many factors, ranging from genetic to environmental. It is also important to remember that fertility disorders can also resu...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.970439/full |
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| author | Anna Bendarska-Czerwińska Anna Bendarska-Czerwińska Anna Bendarska-Czerwińska Nikola Zmarzły Emilia Morawiec Emilia Morawiec Emilia Morawiec Agata Panfil Kamil Bryś Justyna Czarniecka Aleksander Ostenda Konrad Dziobek Dorota Sagan Dariusz Boroń Dariusz Boroń Dariusz Boroń Dariusz Boroń Piotr Michalski Veronica Pallazo-Michalska Beniamin Oskar Grabarek Beniamin Oskar Grabarek Beniamin Oskar Grabarek Beniamin Oskar Grabarek Beniamin Oskar Grabarek |
| author_facet | Anna Bendarska-Czerwińska Anna Bendarska-Czerwińska Anna Bendarska-Czerwińska Nikola Zmarzły Emilia Morawiec Emilia Morawiec Emilia Morawiec Agata Panfil Kamil Bryś Justyna Czarniecka Aleksander Ostenda Konrad Dziobek Dorota Sagan Dariusz Boroń Dariusz Boroń Dariusz Boroń Dariusz Boroń Piotr Michalski Veronica Pallazo-Michalska Beniamin Oskar Grabarek Beniamin Oskar Grabarek Beniamin Oskar Grabarek Beniamin Oskar Grabarek Beniamin Oskar Grabarek |
| author_sort | Anna Bendarska-Czerwińska |
| collection | DOAJ |
| description | It is estimated that more and more couples suffer from fertility and pregnancy maintenance disorders. It is associated with impaired androgen secretion, which is influenced by many factors, ranging from genetic to environmental. It is also important to remember that fertility disorders can also result from abnormal anatomy of the reproductive male and female organ (congenital uterine anomalies – septate, unicornuate, bicornuate uterus; acquired defects of the uterus structure – fibroids, polyps, hypertrophy), disturbed hormonal cycle and obstruction of the fallopian tubes resulting from the presence of adhesions due to inflammation, endometriosis, and surgery, abnormal rhythm of menstrual bleeding, the abnormal concentration of hormones. There are many relationships between the endocrine organs, leading to a chain reaction when one of them fails to function properly. Conditions in which the immune system is involved, including infections and autoimmune diseases, also affect fertility. The form of treatment depends on infertility duration and the patient’s age. It includes ovulation stimulation with clomiphene citrate or gonadotropins, metformin use, and weight loss interventions. Since so many different factors affect fertility, it is important to correctly diagnose what is causing the problem and to modify the treatment regimen if necessary. This review describes disturbances in the hormone secretion of individual endocrine organs in the context of fertility and the maintenance of pregnancy. |
| first_indexed | 2024-04-10T22:29:36Z |
| format | Article |
| id | doaj.art-5c0c449b01cf4d229c3b576a103a863e |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-10T22:29:36Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-5c0c449b01cf4d229c3b576a103a863e2023-01-17T06:06:12ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922023-01-011310.3389/fendo.2022.970439970439Endocrine disorders and fertility and pregnancy: An updateAnna Bendarska-Czerwińska0Anna Bendarska-Czerwińska1Anna Bendarska-Czerwińska2Nikola Zmarzły3Emilia Morawiec4Emilia Morawiec5Emilia Morawiec6Agata Panfil7Kamil Bryś8Justyna Czarniecka9Aleksander Ostenda10Konrad Dziobek11Dorota Sagan12Dariusz Boroń13Dariusz Boroń14Dariusz Boroń15Dariusz Boroń16Piotr Michalski17Veronica Pallazo-Michalska18Beniamin Oskar Grabarek19Beniamin Oskar Grabarek20Beniamin Oskar Grabarek21Beniamin Oskar Grabarek22Beniamin Oskar Grabarek23Department of Molecular, Biology Gyncentrum Fertility Clinic, Katowice, PolandFaculty of Medicine, Academy of Silesia, Zabrze, PolandAmerican Medical Clinic, Katowice, PolandDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology, Academy of Silesia in Katowice, Zabrze, PolandDepartment of Molecular, Biology Gyncentrum Fertility Clinic, Katowice, PolandDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology, Academy of Silesia in Katowice, Zabrze, PolandDepartment of Microbiology, Faculty of Medicine, University of Technology, Academy of Silesia in Katowice, Zabrze, PolandDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology, Academy of Silesia in Katowice, Zabrze, PolandDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology, Academy of Silesia in Katowice, Zabrze, PolandDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology, Academy of Silesia in Katowice, Zabrze, PolandFaculty of Medicine, Academy of Silesia, Zabrze, PolandFaculty of Medicine, Academy of Silesia, Zabrze, PolandMedical Center Dormed Medical SPA, Busko-Zdroj, PolandDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology, Academy of Silesia in Katowice, Zabrze, PolandDepartment of Gynaecology and Obstetrics, Faculty of Medicine, Academy of Silesia, Zabrze, PolandDepartment of Gynecology and Obstetrics with Gynecologic Oncology, Ludwik Rydygier Memorial Specialized Hospital, Kraków, PolandDepartment of Gynecology and Obstetrics, TOMMED Specjalisci od Zdrowia, Katowice, PolandFaculty of Medicine, Academy of Silesia, Zabrze, PolandFaculty of Medicine, Academy of Silesia, Zabrze, PolandDepartment of Molecular, Biology Gyncentrum Fertility Clinic, Katowice, PolandDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology, Academy of Silesia in Katowice, Zabrze, PolandDepartment of Gynaecology and Obstetrics, Faculty of Medicine, Academy of Silesia, Zabrze, PolandDepartment of Gynecology and Obstetrics with Gynecologic Oncology, Ludwik Rydygier Memorial Specialized Hospital, Kraków, PolandDepartment of Gynecology and Obstetrics, TOMMED Specjalisci od Zdrowia, Katowice, PolandIt is estimated that more and more couples suffer from fertility and pregnancy maintenance disorders. It is associated with impaired androgen secretion, which is influenced by many factors, ranging from genetic to environmental. It is also important to remember that fertility disorders can also result from abnormal anatomy of the reproductive male and female organ (congenital uterine anomalies – septate, unicornuate, bicornuate uterus; acquired defects of the uterus structure – fibroids, polyps, hypertrophy), disturbed hormonal cycle and obstruction of the fallopian tubes resulting from the presence of adhesions due to inflammation, endometriosis, and surgery, abnormal rhythm of menstrual bleeding, the abnormal concentration of hormones. There are many relationships between the endocrine organs, leading to a chain reaction when one of them fails to function properly. Conditions in which the immune system is involved, including infections and autoimmune diseases, also affect fertility. The form of treatment depends on infertility duration and the patient’s age. It includes ovulation stimulation with clomiphene citrate or gonadotropins, metformin use, and weight loss interventions. Since so many different factors affect fertility, it is important to correctly diagnose what is causing the problem and to modify the treatment regimen if necessary. This review describes disturbances in the hormone secretion of individual endocrine organs in the context of fertility and the maintenance of pregnancy.https://www.frontiersin.org/articles/10.3389/fendo.2022.970439/fullendocrine disordersfertilityinfertilitypregnancyreproductive healthhormones |
| spellingShingle | Anna Bendarska-Czerwińska Anna Bendarska-Czerwińska Anna Bendarska-Czerwińska Nikola Zmarzły Emilia Morawiec Emilia Morawiec Emilia Morawiec Agata Panfil Kamil Bryś Justyna Czarniecka Aleksander Ostenda Konrad Dziobek Dorota Sagan Dariusz Boroń Dariusz Boroń Dariusz Boroń Dariusz Boroń Piotr Michalski Veronica Pallazo-Michalska Beniamin Oskar Grabarek Beniamin Oskar Grabarek Beniamin Oskar Grabarek Beniamin Oskar Grabarek Beniamin Oskar Grabarek Endocrine disorders and fertility and pregnancy: An update Frontiers in Endocrinology endocrine disorders fertility infertility pregnancy reproductive health hormones |
| title | Endocrine disorders and fertility and pregnancy: An update |
| title_full | Endocrine disorders and fertility and pregnancy: An update |
| title_fullStr | Endocrine disorders and fertility and pregnancy: An update |
| title_full_unstemmed | Endocrine disorders and fertility and pregnancy: An update |
| title_short | Endocrine disorders and fertility and pregnancy: An update |
| title_sort | endocrine disorders and fertility and pregnancy an update |
| topic | endocrine disorders fertility infertility pregnancy reproductive health hormones |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2022.970439/full |
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