Disruption of Foxg1 impairs neural plasticity leading to social and cognitive behavioral defects

Disruption of Foxg1 impairs neural plasticity leading to social and cognitive behavioral defects

Abstract The transcription factor Foxg1 is known to be continuously expressed at a high level in mature neurons in the telencephalon, but little is known about its role in neural plasticity. Mutations in human FOXG1 cause deficiencies in learning and memory and limit social ability, which is defined...

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Bibliographic Details
Main Authors: Baocong Yu, Junhua Liu, Mingzhao Su, Chunlian Wang, Huanxin Chen, Chunjie Zhao
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Molecular Brain
Subjects:
Neural plasticity
Dendritic arborization
Spine
Spatial learning and memory
Foxg1
FOXG1 syndrome
Online Access:http://link.springer.com/article/10.1186/s13041-019-0484-x

Internet

http://link.springer.com/article/10.1186/s13041-019-0484-x

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