Function of B-Cell CLL/Lymphoma 11B in Glial Progenitor Proliferation and Oligodendrocyte Maturation

Function of B-Cell CLL/Lymphoma 11B in Glial Progenitor Proliferation and Oligodendrocyte Maturation

B-cell CLL/lymphoma 11B (Bcl11b) – a C2H2 zinc finger transcriptional factor – is known to regulate neuronal differentiation and function in the development of the central nervous system (CNS). Although its expression is reduced during oligodendrocyte (OLG) differentiation, its biological role in OL...

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Bibliographic Details
Main Authors: Chih-Yen Wang, Yuan-Ting Sun, Kuan-Min Fang, Chia-Hsin Ho, Chung-Shi Yang, Shun-Fen Tzeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Bcl11b
glia
oligodendrocytes
glial progenitors
differentiation and proliferation
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2018.00004/full

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