Imaging Features of Pediatric Left Ventricular Noncompaction Cardiomyopathy in Echocardiography and Cardiovascular Magnetic Resonance
<i><span style="text-decoration: underline;">Background:</span></i> Left ventricular noncompaction (LVNC) is a distinct cardiomyopathy characterized by the presence of a two-layer myocardium with prominent trabeculation and deep intertrabecular recesses. The diagnos...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-03-01
|
Series: | Journal of Cardiovascular Development and Disease |
Subjects: | |
Online Access: | https://www.mdpi.com/2308-3425/9/3/77 |
_version_ | 1797470603771379712 |
---|---|
author | Agata Paszkowska Jędrzej Sarnecki Alicja Mirecka-Rola Monika Kowalczyk-Domagała Łukasz Mazurkiewicz Lidia Ziółkowska |
author_facet | Agata Paszkowska Jędrzej Sarnecki Alicja Mirecka-Rola Monika Kowalczyk-Domagała Łukasz Mazurkiewicz Lidia Ziółkowska |
author_sort | Agata Paszkowska |
collection | DOAJ |
description | <i><span style="text-decoration: underline;">Background:</span></i> Left ventricular noncompaction (LVNC) is a distinct cardiomyopathy characterized by the presence of a two-layer myocardium with prominent trabeculation and deep intertrabecular recesses. The diagnosis of LVNC can be challenging because the diagnostic criteria are not uniform. The aim of our study was to evaluate echocardiographic and CMR findings in a group of children with isolated LVNC. <span style="text-decoration: underline;"><i>Methods:</i></span> From February 2008 to July 2021, pediatric patients under 18 years of age at the time of diagnosis with echocardiographic evidence of isolated LVNC were prospectively enrolled. The patients underwent echocardiography and contrast-enhanced cardiovascular magnetic resonance (CMR) with late gadolinium enhancement to assess myocardial noncompaction, ventricular size, and function. <span style="text-decoration: underline;"><i>Results:</i></span> A total of 34 patients, with a median age of 11.9 years, were recruited. The patients were followed prospectively for a median of 5.1 years. Of the 31 patients who met Jenni’s criteria in echocardiography, CMR was performed on 27 (79%). Further comprehensive analysis was performed in the group of 25 patients who met the echocardiographic and CMR criteria for LVNC. In echocardiography, the median NC/C ratio in systole was 2.60 and in diastole 3.40. In 25 out of 27 children (93%), LVNC was confirmed by CMR, according to Petersen’s criteria, with a median NC/C ratio of 3.27. <span style="text-decoration: underline;"><i>Conclusions:</i></span> (1) Echocardiography precisely identifies patients with LVNC. (2) Echocardiography is a good method for monitoring LV systolic function, but CMR is indicated for the precise assessment of LV remodeling and RV size and function, as well as for the detection of myocardial fibrosis. |
first_indexed | 2024-03-09T19:38:43Z |
format | Article |
id | doaj.art-5c146cb1787048bd8689deb241210de0 |
institution | Directory Open Access Journal |
issn | 2308-3425 |
language | English |
last_indexed | 2024-03-09T19:38:43Z |
publishDate | 2022-03-01 |
publisher | MDPI AG |
record_format | Article |
series | Journal of Cardiovascular Development and Disease |
spelling | doaj.art-5c146cb1787048bd8689deb241210de02023-11-24T01:46:04ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252022-03-01937710.3390/jcdd9030077Imaging Features of Pediatric Left Ventricular Noncompaction Cardiomyopathy in Echocardiography and Cardiovascular Magnetic ResonanceAgata Paszkowska0Jędrzej Sarnecki1Alicja Mirecka-Rola2Monika Kowalczyk-Domagała3Łukasz Mazurkiewicz4Lidia Ziółkowska5Department of Cardiology, The Children’s Memorial Health Institute, Al. Dzieci Polskich 20, 04-730 Warsaw, PolandDepartment of Diagnostic Imaging, The Children’s Memorial Health Institute, 04-730 Warsaw, PolandDepartment of Cardiology, The Children’s Memorial Health Institute, Al. Dzieci Polskich 20, 04-730 Warsaw, PolandDepartment of Cardiology, The Children’s Memorial Health Institute, Al. Dzieci Polskich 20, 04-730 Warsaw, PolandCardiovascular Magnetic Resonance Unit, Department of Cardiomyopathies, National Institute of Cardiology, 04-682 Warsaw, PolandDepartment of Cardiology, The Children’s Memorial Health Institute, Al. Dzieci Polskich 20, 04-730 Warsaw, Poland<i><span style="text-decoration: underline;">Background:</span></i> Left ventricular noncompaction (LVNC) is a distinct cardiomyopathy characterized by the presence of a two-layer myocardium with prominent trabeculation and deep intertrabecular recesses. The diagnosis of LVNC can be challenging because the diagnostic criteria are not uniform. The aim of our study was to evaluate echocardiographic and CMR findings in a group of children with isolated LVNC. <span style="text-decoration: underline;"><i>Methods:</i></span> From February 2008 to July 2021, pediatric patients under 18 years of age at the time of diagnosis with echocardiographic evidence of isolated LVNC were prospectively enrolled. The patients underwent echocardiography and contrast-enhanced cardiovascular magnetic resonance (CMR) with late gadolinium enhancement to assess myocardial noncompaction, ventricular size, and function. <span style="text-decoration: underline;"><i>Results:</i></span> A total of 34 patients, with a median age of 11.9 years, were recruited. The patients were followed prospectively for a median of 5.1 years. Of the 31 patients who met Jenni’s criteria in echocardiography, CMR was performed on 27 (79%). Further comprehensive analysis was performed in the group of 25 patients who met the echocardiographic and CMR criteria for LVNC. In echocardiography, the median NC/C ratio in systole was 2.60 and in diastole 3.40. In 25 out of 27 children (93%), LVNC was confirmed by CMR, according to Petersen’s criteria, with a median NC/C ratio of 3.27. <span style="text-decoration: underline;"><i>Conclusions:</i></span> (1) Echocardiography precisely identifies patients with LVNC. (2) Echocardiography is a good method for monitoring LV systolic function, but CMR is indicated for the precise assessment of LV remodeling and RV size and function, as well as for the detection of myocardial fibrosis.https://www.mdpi.com/2308-3425/9/3/77left ventricular noncompactioncardiomyopathyimagingechocardiographycardiovascular magnetic resonancechildren |
spellingShingle | Agata Paszkowska Jędrzej Sarnecki Alicja Mirecka-Rola Monika Kowalczyk-Domagała Łukasz Mazurkiewicz Lidia Ziółkowska Imaging Features of Pediatric Left Ventricular Noncompaction Cardiomyopathy in Echocardiography and Cardiovascular Magnetic Resonance Journal of Cardiovascular Development and Disease left ventricular noncompaction cardiomyopathy imaging echocardiography cardiovascular magnetic resonance children |
title | Imaging Features of Pediatric Left Ventricular Noncompaction Cardiomyopathy in Echocardiography and Cardiovascular Magnetic Resonance |
title_full | Imaging Features of Pediatric Left Ventricular Noncompaction Cardiomyopathy in Echocardiography and Cardiovascular Magnetic Resonance |
title_fullStr | Imaging Features of Pediatric Left Ventricular Noncompaction Cardiomyopathy in Echocardiography and Cardiovascular Magnetic Resonance |
title_full_unstemmed | Imaging Features of Pediatric Left Ventricular Noncompaction Cardiomyopathy in Echocardiography and Cardiovascular Magnetic Resonance |
title_short | Imaging Features of Pediatric Left Ventricular Noncompaction Cardiomyopathy in Echocardiography and Cardiovascular Magnetic Resonance |
title_sort | imaging features of pediatric left ventricular noncompaction cardiomyopathy in echocardiography and cardiovascular magnetic resonance |
topic | left ventricular noncompaction cardiomyopathy imaging echocardiography cardiovascular magnetic resonance children |
url | https://www.mdpi.com/2308-3425/9/3/77 |
work_keys_str_mv | AT agatapaszkowska imagingfeaturesofpediatricleftventricularnoncompactioncardiomyopathyinechocardiographyandcardiovascularmagneticresonance AT jedrzejsarnecki imagingfeaturesofpediatricleftventricularnoncompactioncardiomyopathyinechocardiographyandcardiovascularmagneticresonance AT alicjamireckarola imagingfeaturesofpediatricleftventricularnoncompactioncardiomyopathyinechocardiographyandcardiovascularmagneticresonance AT monikakowalczykdomagała imagingfeaturesofpediatricleftventricularnoncompactioncardiomyopathyinechocardiographyandcardiovascularmagneticresonance AT łukaszmazurkiewicz imagingfeaturesofpediatricleftventricularnoncompactioncardiomyopathyinechocardiographyandcardiovascularmagneticresonance AT lidiaziołkowska imagingfeaturesofpediatricleftventricularnoncompactioncardiomyopathyinechocardiographyandcardiovascularmagneticresonance |