Emerging role of long non-coding RNA SOX2OT in SOX2 regulation in breast cancer.

The transcription factor SOX2 is essential for maintaining pluripotency in a variety of stem cells. It has important functions during embryonic development, is involved in cancer stem cell maintenance, and is often deregulated in cancer. The mechanism of SOX2 regulation has yet to be clarified, but...

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Bibliographic Details
Main Authors: Marjan E Askarian-Amiri, Vahid Seyfoddin, Chanel E Smart, Jingli Wang, Ji Eun Kim, Herah Hansji, Bruce C Baguley, Graeme J Finlay, Euphemia Y Leung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4090206?pdf=render

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