Pan-cancer clinical impact of latent drivers from double mutations
A statistical methodology is used to identify potential ‘latent driver’ mutations from public cancer bulk sequencing data.
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-02-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-04519-5 |
| _version_ | 1797863802445758464 |
|---|---|
| author | Bengi Ruken Yavuz Chung-Jung Tsai Ruth Nussinov Nurcan Tuncbag |
| author_facet | Bengi Ruken Yavuz Chung-Jung Tsai Ruth Nussinov Nurcan Tuncbag |
| author_sort | Bengi Ruken Yavuz |
| collection | DOAJ |
| description | A statistical methodology is used to identify potential ‘latent driver’ mutations from public cancer bulk sequencing data. |
| first_indexed | 2024-04-09T22:42:35Z |
| format | Article |
| id | doaj.art-5c174c09cf484acb9f4bca5939255a1c |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-09T22:42:35Z |
| publishDate | 2023-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-5c174c09cf484acb9f4bca5939255a1c2023-03-22T12:04:50ZengNature PortfolioCommunications Biology2399-36422023-02-016111410.1038/s42003-023-04519-5Pan-cancer clinical impact of latent drivers from double mutationsBengi Ruken Yavuz0Chung-Jung Tsai1Ruth Nussinov2Nurcan Tuncbag3Graduate School of Informatics, Department of Health Informatics, Middle East Technical UniversityComputational Structural Biology Section, Frederick National Laboratory for Cancer Research, National Cancer Institute at FrederickComputational Structural Biology Section, Frederick National Laboratory for Cancer Research, National Cancer Institute at FrederickDepartment of Chemical and Biological Engineering, College of Engineering, Koç UniversityA statistical methodology is used to identify potential ‘latent driver’ mutations from public cancer bulk sequencing data.https://doi.org/10.1038/s42003-023-04519-5 |
| spellingShingle | Bengi Ruken Yavuz Chung-Jung Tsai Ruth Nussinov Nurcan Tuncbag Pan-cancer clinical impact of latent drivers from double mutations Communications Biology |
| title | Pan-cancer clinical impact of latent drivers from double mutations |
| title_full | Pan-cancer clinical impact of latent drivers from double mutations |
| title_fullStr | Pan-cancer clinical impact of latent drivers from double mutations |
| title_full_unstemmed | Pan-cancer clinical impact of latent drivers from double mutations |
| title_short | Pan-cancer clinical impact of latent drivers from double mutations |
| title_sort | pan cancer clinical impact of latent drivers from double mutations |
| url | https://doi.org/10.1038/s42003-023-04519-5 |
| work_keys_str_mv | AT bengirukenyavuz pancancerclinicalimpactoflatentdriversfromdoublemutations AT chungjungtsai pancancerclinicalimpactoflatentdriversfromdoublemutations AT ruthnussinov pancancerclinicalimpactoflatentdriversfromdoublemutations AT nurcantuncbag pancancerclinicalimpactoflatentdriversfromdoublemutations |