Development and validation of a new asthma questionnaire to help achieve a high level of control in school-age children and adolescents
Background: Maintaining good asthma control minimizes the risk of exacerbations and lung function decline and is a primary goal of asthma management. The Japanese Pediatric Asthma Guidelines (JPGL) employs different classification criteria for control status from other guidelines, stressing a higher...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | Allergology International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1323893023001132 |
| _version_ | 1797238039830855680 |
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| author | Mayumi Matsunaga Yasunori Sato Mizuho Nagao Masanori Ikeda Chikako Motomura Makoto Kameda Yukinori Yoshida Akihiko Terada Isao Miyairi Takao Fujisawa |
| author_facet | Mayumi Matsunaga Yasunori Sato Mizuho Nagao Masanori Ikeda Chikako Motomura Makoto Kameda Yukinori Yoshida Akihiko Terada Isao Miyairi Takao Fujisawa |
| author_sort | Mayumi Matsunaga |
| collection | DOAJ |
| description | Background: Maintaining good asthma control minimizes the risk of exacerbations and lung function decline and is a primary goal of asthma management. The Japanese Pediatric Asthma Guidelines (JPGL) employs different classification criteria for control status from other guidelines, stressing a higher level of control. Based on JPGL, we previously developed a caregiver-completed questionnaire for assessing and achieving best asthma control in preschoolers. In this study, we aimed to develop a questionnaire for school-age children and adolescents. Methods: A working questionnaire comprising 14 items for patients and 34 items for caregivers was administered to 362 asthma patients aged 6–15 years and their caregivers. Separately, physicians filled out a questionnaire to determine JPGL-defined control. Logistic regression analysis was performed to construct a model to predict control levels using data from a randomly selected set of completed questionnaires from two-thirds of the subjects. Validation was performed using the remaining questionnaires. Results: A set of 7 questions, encompassing self-assessed control status at the time of the visit and in the past month, and nocturnal/early morning asthma symptoms for patients and frequency of asthma symptoms, dyspnea, rescue beta-agonist use, and asthma hospitalization for caregivers, were selected and the 7-item model showed a good statistical fit with AIC of 110.5. The model has been named the Best Asthma Control Test for School Children and Adolescents (Best ACT-S). Best ACT-S scores differed significantly in the hypothetical direction among the groups of different JPGL-defined control levels, step-up/down treatment decisions, and presence/non-presence of exacerbations in the previous year. Conclusions: The Best ACT-S is a valid questionnaire for children/adolescents aiming for best asthma control. |
| first_indexed | 2024-04-24T17:29:19Z |
| format | Article |
| id | doaj.art-5c1c74b4605a4d34abf65a50ecbb1469 |
| institution | Directory Open Access Journal |
| issn | 1323-8930 |
| language | English |
| last_indexed | 2024-04-24T17:29:19Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Allergology International |
| spelling | doaj.art-5c1c74b4605a4d34abf65a50ecbb14692024-03-28T06:37:16ZengElsevierAllergology International1323-89302024-04-01732224230Development and validation of a new asthma questionnaire to help achieve a high level of control in school-age children and adolescentsMayumi Matsunaga0Yasunori Sato1Mizuho Nagao2Masanori Ikeda3Chikako Motomura4Makoto Kameda5Yukinori Yoshida6Akihiko Terada7Isao Miyairi8Takao Fujisawa9Allergy Center, National Hospital Organization Mie National Hospital, Mie, Japan; Department of Pediatrics, Hamamatsu University Graduate School of Medicine, Hamamatsu, JapanDepartment of Preventive Medicine and Public Health, Keio University School of Medicine, Tokyo, JapanAllergy Center, National Hospital Organization Mie National Hospital, Mie, JapanDepartment of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, JapanDepartment of Pediatrics, National Hospital Organization Fukuoka National Hospital, Fukuoka, JapanDepartment of Pediatrics, Osaka Habikino Medical Center, Osaka, JapanDepartment of Pediatrics, Osaka Habikino Medical Center, Osaka, JapanTerada Allergy and Pediatrics Clinic, Nagoya, JapanDepartment of Pediatrics, Hamamatsu University Graduate School of Medicine, Hamamatsu, JapanAllergy Center, National Hospital Organization Mie National Hospital, Mie, Japan; Corresponding author. Allergy Center, National Hospital Organization Mie National Hospital, 357 Osato-kubota, Tsu, Mie 514-0125, Japan.Background: Maintaining good asthma control minimizes the risk of exacerbations and lung function decline and is a primary goal of asthma management. The Japanese Pediatric Asthma Guidelines (JPGL) employs different classification criteria for control status from other guidelines, stressing a higher level of control. Based on JPGL, we previously developed a caregiver-completed questionnaire for assessing and achieving best asthma control in preschoolers. In this study, we aimed to develop a questionnaire for school-age children and adolescents. Methods: A working questionnaire comprising 14 items for patients and 34 items for caregivers was administered to 362 asthma patients aged 6–15 years and their caregivers. Separately, physicians filled out a questionnaire to determine JPGL-defined control. Logistic regression analysis was performed to construct a model to predict control levels using data from a randomly selected set of completed questionnaires from two-thirds of the subjects. Validation was performed using the remaining questionnaires. Results: A set of 7 questions, encompassing self-assessed control status at the time of the visit and in the past month, and nocturnal/early morning asthma symptoms for patients and frequency of asthma symptoms, dyspnea, rescue beta-agonist use, and asthma hospitalization for caregivers, were selected and the 7-item model showed a good statistical fit with AIC of 110.5. The model has been named the Best Asthma Control Test for School Children and Adolescents (Best ACT-S). Best ACT-S scores differed significantly in the hypothetical direction among the groups of different JPGL-defined control levels, step-up/down treatment decisions, and presence/non-presence of exacerbations in the previous year. Conclusions: The Best ACT-S is a valid questionnaire for children/adolescents aiming for best asthma control.http://www.sciencedirect.com/science/article/pii/S1323893023001132AsthmaChildrenControl statusGuidelinesQuestionnaire |
| spellingShingle | Mayumi Matsunaga Yasunori Sato Mizuho Nagao Masanori Ikeda Chikako Motomura Makoto Kameda Yukinori Yoshida Akihiko Terada Isao Miyairi Takao Fujisawa Development and validation of a new asthma questionnaire to help achieve a high level of control in school-age children and adolescents Allergology International Asthma Children Control status Guidelines Questionnaire |
| title | Development and validation of a new asthma questionnaire to help achieve a high level of control in school-age children and adolescents |
| title_full | Development and validation of a new asthma questionnaire to help achieve a high level of control in school-age children and adolescents |
| title_fullStr | Development and validation of a new asthma questionnaire to help achieve a high level of control in school-age children and adolescents |
| title_full_unstemmed | Development and validation of a new asthma questionnaire to help achieve a high level of control in school-age children and adolescents |
| title_short | Development and validation of a new asthma questionnaire to help achieve a high level of control in school-age children and adolescents |
| title_sort | development and validation of a new asthma questionnaire to help achieve a high level of control in school age children and adolescents |
| topic | Asthma Children Control status Guidelines Questionnaire |
| url | http://www.sciencedirect.com/science/article/pii/S1323893023001132 |
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