Cholesterol accumulation in ovarian follicles causes ovulation defects in Abca1a−/− Japanese medaka (Oryzias latipes)
ATP-binding cassette A1 (ABCA1) is a membrane protein, which exports excess cellular cholesterol to generate HDL to reduce the risk of the onset of cardiovascular diseases (CVD). In addition, ABCA1 exerts pleiotropic effects on such as inflammation, tissue repair, and cell proliferation and migratio...
Main Authors: | Ryota Futamata, Masato Kinoshita, Katsueki Ogiwara, Noriyuki Kioka, Kazumitsu Ueda |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-02-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S240584402300498X |
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