3D Printed Cell Culture Chamber for Testing the Effect of Pump-Based Chronic Drug Delivery on Inner Ear Tissue

3D Printed Cell Culture Chamber for Testing the Effect of Pump-Based Chronic Drug Delivery on Inner Ear Tissue

Cochlear hair cell damage and spiral ganglion neuron (SGN) degeneration are the main causes of sensory neural hearing loss. Cochlear implants (CIs) can replace the function of the hair cells and stimulate the SGNs electrically. The condition of the SGNs and their spatial distance to the CI are key f...

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Bibliographic Details
Main Authors: Jana Schwieger, Anna Sophie Frisch, Thomas S. Rau, Thomas Lenarz, Silke Hügl, Verena Scheper
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biomolecules
Subjects:
auditory neurons
cochlear implant
cell culture chamber
neurite outgrowth
neurite guidance
ciliary neurotrophic factor
Online Access:https://www.mdpi.com/2218-273X/12/4/589

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