High-Metastatic Melanoma Cells Promote the Metastatic Capability of Low-Metastatic Melanoma Cells via Exosomal Transfer of miR-411-5p

High-Metastatic Melanoma Cells Promote the Metastatic Capability of Low-Metastatic Melanoma Cells via Exosomal Transfer of miR-411-5p

Melanoma is characterized by high rate of metastasis and mortality. Effective management of metastatic melanoma depends on renewed mechanistic understanding underlying melanoma progression and metastasis. The role of exosomes in mediating the interactions between cancer cells and the metastatic micr...

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Bibliographic Details
Main Authors: Hao Chen, Bin Zeng, Xiaoshuang Li, Qiting Zhao, Doudou Liu, Yuting Chen, Yuhan Zhang, Jianyu Wang, H. Rosie Xing
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Oncology
Subjects:
exosome
metastatic microenvironment
melanoma
miR-411-5p
mitogen-activated protein kinase (MAPK) signal pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.895164/full

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