Hepatic amebiasis: experience in the therapy of 56 cases.

The results of therapy in 56 consecutive cases of hepatic amebiasis are reviewed. In retrospect, the results in patients receiving metronidazole alone, dehydroemetine combined with chloroquine, and dehydroemetine combined with chloroquine and metronidazole were compared. No deaths occured. Our resu...

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Main Authors: Ireneu Cruz, F. J. Z. Carneiro Chaves
Format: Article
Language:English
Published: Ordem dos Médicos 1981-12-01
Series:Acta Médica Portuguesa
Online Access:https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3911
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author Ireneu Cruz
F. J. Z. Carneiro Chaves
author_facet Ireneu Cruz
F. J. Z. Carneiro Chaves
author_sort Ireneu Cruz
collection DOAJ
description The results of therapy in 56 consecutive cases of hepatic amebiasis are reviewed. In retrospect, the results in patients receiving metronidazole alone, dehydroemetine combined with chloroquine, and dehydroemetine combined with chloroquine and metronidazole were compared. No deaths occured. Our results confirm the great efficacy of metronidazole alone. The response to treatment was similar in patients receiving dehydroemetine combined with chloroquine but the average number of days of hospitalization was greater in these patients. No advantage was demonstrated for the combination of metronidazole with dehydroemetine and chloroquine. In retrospect these patients proved to have a more severe and protracted course with more frequent surgical complications and a greater need for closed aspiration of the abscess. Closed aspiration, not used routinely, has not reduced the number of days of hospitalization. Significant side effects were not observed.
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spelling doaj.art-5c274721fbd440b3b2d9b49195386b7a2022-12-22T04:30:01ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07581981-12-01310.20344/amp.3911Hepatic amebiasis: experience in the therapy of 56 cases.Ireneu Cruz0F. J. Z. Carneiro Chaves1Serviço 2. Medicina. Hospital de Curry Cabral. Lisboa. PortugalServiço de Terapêutica Medica (Medicina II). Faculdade de Medicina. Hospital de S. Joao. Porto. Portugal The results of therapy in 56 consecutive cases of hepatic amebiasis are reviewed. In retrospect, the results in patients receiving metronidazole alone, dehydroemetine combined with chloroquine, and dehydroemetine combined with chloroquine and metronidazole were compared. No deaths occured. Our results confirm the great efficacy of metronidazole alone. The response to treatment was similar in patients receiving dehydroemetine combined with chloroquine but the average number of days of hospitalization was greater in these patients. No advantage was demonstrated for the combination of metronidazole with dehydroemetine and chloroquine. In retrospect these patients proved to have a more severe and protracted course with more frequent surgical complications and a greater need for closed aspiration of the abscess. Closed aspiration, not used routinely, has not reduced the number of days of hospitalization. Significant side effects were not observed. https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3911
spellingShingle Ireneu Cruz
F. J. Z. Carneiro Chaves
Hepatic amebiasis: experience in the therapy of 56 cases.
Acta Médica Portuguesa
title Hepatic amebiasis: experience in the therapy of 56 cases.
title_full Hepatic amebiasis: experience in the therapy of 56 cases.
title_fullStr Hepatic amebiasis: experience in the therapy of 56 cases.
title_full_unstemmed Hepatic amebiasis: experience in the therapy of 56 cases.
title_short Hepatic amebiasis: experience in the therapy of 56 cases.
title_sort hepatic amebiasis experience in the therapy of 56 cases
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3911
work_keys_str_mv AT ireneucruz hepaticamebiasisexperienceinthetherapyof56cases
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