In-hospital electrical muscle stimulation for patients early after heart failure decompensation: results from a prospective randomised controlled pilot trial
Background Electrical muscle stimulation (EMS) is being evaluated as a possible alternative to exercise training to improve functional capacity in severely deconditioned patients with heart failure (HF). However, there is insufficient data on delayed effects of EMS starting early after decompensatio...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2022-12-01
|
| Series: | Open Heart |
| Online Access: | https://openheart.bmj.com/content/9/2/e001965.full |
| _version_ | 1797792153956515840 |
|---|---|
| author | Hugo Saner Elena Tomilovskaya Maria Poltavskaya Denis Andreev Victoria Sviridenko Ilya Giverts Irina Patchenskaya Inesa Kozlovskaya Gabil Orkhan Veliyev Abram Syrkin |
| author_facet | Hugo Saner Elena Tomilovskaya Maria Poltavskaya Denis Andreev Victoria Sviridenko Ilya Giverts Irina Patchenskaya Inesa Kozlovskaya Gabil Orkhan Veliyev Abram Syrkin |
| author_sort | Hugo Saner |
| collection | DOAJ |
| description | Background Electrical muscle stimulation (EMS) is being evaluated as a possible alternative to exercise training to improve functional capacity in severely deconditioned patients with heart failure (HF). However, there is insufficient data on delayed effects of EMS starting early after decompensation. The aim of this study was to determine the impact of a short inpatient EMS intervention in severely deconditioned patients with HF on functional capacity and quality of life (QoL) over a follow-up period of 1 month.Methods This is a prospective randomised sham-controlled pilot study. 45 patients hospitalised for decompensated systolic HF (58% men, mean age 66.4±10.2 years) were randomised to EMS (n=22) or sham stimulation (n=23) of lower limbs starting within 3 days after admission. The intervention included 7–10 sessions lasting from 30 to 90 min. The 6-minute walking test distance (6-MWTD), Duke Activity Status Index (DASI) and Minnesota Living with Heart Failure Questionnaire (MLHFQ) were evaluated at baseline, discharge and after 1 month.Results All patients completed the programme with good EMS tolerance. 37 patients were included in the final analysis. At discharge, 6-MWTD improved from 206,1±61,3 to 299.5±91 m, DASI from 12.1±5.6 to 18.3±7.2 and MLHFQ from 55.6±8.5 to 34.2±9 with EMS compared with smaller improvements in the sham group (p<0.05 for all). One month after discharge, improvements in the EMS group remained significant for MLHFQ (p=0.004) and DASI (p=0.042) and statistically non-significant for 6-MWTD compared with the sham group.Conclusions Short-term in-hospital EMS leads to improvements in functional capacity and QoL in selected patients early after HF decompensation that are retained over 1 month after discharge and therefore may serve as initial intervention to improve physical capacity or as a bridge to further conventional exercise training. Larger studies are required to evaluate individual responses to an early initiation of EMS in decompensated HF as well as long-term effects. |
| first_indexed | 2024-03-13T02:29:08Z |
| format | Article |
| id | doaj.art-5c2a42ed4b984da0b847dec454879189 |
| institution | Directory Open Access Journal |
| issn | 2053-3624 |
| language | English |
| last_indexed | 2024-03-13T02:29:08Z |
| publishDate | 2022-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | Open Heart |
| spelling | doaj.art-5c2a42ed4b984da0b847dec4548791892023-06-30T01:30:07ZengBMJ Publishing GroupOpen Heart2053-36242022-12-019210.1136/openhrt-2022-001965In-hospital electrical muscle stimulation for patients early after heart failure decompensation: results from a prospective randomised controlled pilot trialHugo Saner0Elena Tomilovskaya1Maria Poltavskaya2Denis Andreev3Victoria Sviridenko4Ilya Giverts5Irina Patchenskaya6Inesa Kozlovskaya7Gabil Orkhan Veliyev8Abram Syrkin9Department of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian FederationSensory-Motor Physiology and Countermeasures, Institute of Biomedical Problems RAS, Moscow, Russian FederationDepartment of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian FederationDepartment of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian FederationDepartment of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian FederationRehabilitation, City Clinical Hospital #1, Moscow, Russian FederationDepartment of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian FederationSensory-Motor Physiology and Countermeasures, Institute of Biomedical Problems RAS, Moscow, Russian FederationDepartment of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian FederationDepartment of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian FederationBackground Electrical muscle stimulation (EMS) is being evaluated as a possible alternative to exercise training to improve functional capacity in severely deconditioned patients with heart failure (HF). However, there is insufficient data on delayed effects of EMS starting early after decompensation. The aim of this study was to determine the impact of a short inpatient EMS intervention in severely deconditioned patients with HF on functional capacity and quality of life (QoL) over a follow-up period of 1 month.Methods This is a prospective randomised sham-controlled pilot study. 45 patients hospitalised for decompensated systolic HF (58% men, mean age 66.4±10.2 years) were randomised to EMS (n=22) or sham stimulation (n=23) of lower limbs starting within 3 days after admission. The intervention included 7–10 sessions lasting from 30 to 90 min. The 6-minute walking test distance (6-MWTD), Duke Activity Status Index (DASI) and Minnesota Living with Heart Failure Questionnaire (MLHFQ) were evaluated at baseline, discharge and after 1 month.Results All patients completed the programme with good EMS tolerance. 37 patients were included in the final analysis. At discharge, 6-MWTD improved from 206,1±61,3 to 299.5±91 m, DASI from 12.1±5.6 to 18.3±7.2 and MLHFQ from 55.6±8.5 to 34.2±9 with EMS compared with smaller improvements in the sham group (p<0.05 for all). One month after discharge, improvements in the EMS group remained significant for MLHFQ (p=0.004) and DASI (p=0.042) and statistically non-significant for 6-MWTD compared with the sham group.Conclusions Short-term in-hospital EMS leads to improvements in functional capacity and QoL in selected patients early after HF decompensation that are retained over 1 month after discharge and therefore may serve as initial intervention to improve physical capacity or as a bridge to further conventional exercise training. Larger studies are required to evaluate individual responses to an early initiation of EMS in decompensated HF as well as long-term effects.https://openheart.bmj.com/content/9/2/e001965.full |
| spellingShingle | Hugo Saner Elena Tomilovskaya Maria Poltavskaya Denis Andreev Victoria Sviridenko Ilya Giverts Irina Patchenskaya Inesa Kozlovskaya Gabil Orkhan Veliyev Abram Syrkin In-hospital electrical muscle stimulation for patients early after heart failure decompensation: results from a prospective randomised controlled pilot trial Open Heart |
| title | In-hospital electrical muscle stimulation for patients early after heart failure decompensation: results from a prospective randomised controlled pilot trial |
| title_full | In-hospital electrical muscle stimulation for patients early after heart failure decompensation: results from a prospective randomised controlled pilot trial |
| title_fullStr | In-hospital electrical muscle stimulation for patients early after heart failure decompensation: results from a prospective randomised controlled pilot trial |
| title_full_unstemmed | In-hospital electrical muscle stimulation for patients early after heart failure decompensation: results from a prospective randomised controlled pilot trial |
| title_short | In-hospital electrical muscle stimulation for patients early after heart failure decompensation: results from a prospective randomised controlled pilot trial |
| title_sort | in hospital electrical muscle stimulation for patients early after heart failure decompensation results from a prospective randomised controlled pilot trial |
| url | https://openheart.bmj.com/content/9/2/e001965.full |
| work_keys_str_mv | AT hugosaner inhospitalelectricalmusclestimulationforpatientsearlyafterheartfailuredecompensationresultsfromaprospectiverandomisedcontrolledpilottrial AT elenatomilovskaya inhospitalelectricalmusclestimulationforpatientsearlyafterheartfailuredecompensationresultsfromaprospectiverandomisedcontrolledpilottrial AT mariapoltavskaya inhospitalelectricalmusclestimulationforpatientsearlyafterheartfailuredecompensationresultsfromaprospectiverandomisedcontrolledpilottrial AT denisandreev inhospitalelectricalmusclestimulationforpatientsearlyafterheartfailuredecompensationresultsfromaprospectiverandomisedcontrolledpilottrial AT victoriasviridenko inhospitalelectricalmusclestimulationforpatientsearlyafterheartfailuredecompensationresultsfromaprospectiverandomisedcontrolledpilottrial AT ilyagiverts inhospitalelectricalmusclestimulationforpatientsearlyafterheartfailuredecompensationresultsfromaprospectiverandomisedcontrolledpilottrial AT irinapatchenskaya inhospitalelectricalmusclestimulationforpatientsearlyafterheartfailuredecompensationresultsfromaprospectiverandomisedcontrolledpilottrial AT inesakozlovskaya inhospitalelectricalmusclestimulationforpatientsearlyafterheartfailuredecompensationresultsfromaprospectiverandomisedcontrolledpilottrial AT gabilorkhanveliyev inhospitalelectricalmusclestimulationforpatientsearlyafterheartfailuredecompensationresultsfromaprospectiverandomisedcontrolledpilottrial AT abramsyrkin inhospitalelectricalmusclestimulationforpatientsearlyafterheartfailuredecompensationresultsfromaprospectiverandomisedcontrolledpilottrial |