The Persian Version of the Chronic Urticaria Quality of Life Questionnaire: Factor Analysis, Validation, and Initial Clinical Findings
Chronic urticaria (CU) also known as chronic idiopathic urticaria results in a lowered quality of life (QoL). Disease specific questionnaires are necessary to assess QoL in CU patients. Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL) is the only available and validated disease specific que...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2014-08-01
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| Series: | Iranian Journal of Allergy, Asthma and Immunology |
| Subjects: | |
| Online Access: | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/445 |
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| author | Marzieh Tavakol Payam Mohammadinejad Ilaria Baiardini Fulvio Braido Mohammad Gharagozlou Asghar Aghamohammadi Mohammad Nabavi Abbas Dabbaghzade Zahra Tavakol Mohsen Afarideh Nima Rezaei Masoud Movahedi |
| author_facet | Marzieh Tavakol Payam Mohammadinejad Ilaria Baiardini Fulvio Braido Mohammad Gharagozlou Asghar Aghamohammadi Mohammad Nabavi Abbas Dabbaghzade Zahra Tavakol Mohsen Afarideh Nima Rezaei Masoud Movahedi |
| author_sort | Marzieh Tavakol |
| collection | DOAJ |
| description | Chronic urticaria (CU) also known as chronic idiopathic urticaria results in a lowered quality of life (QoL). Disease specific questionnaires are necessary to assess QoL in CU patients. Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL) is the only available and validated disease specific questionnaire in the assessment of QoL in CU patients originally developed in Italian language. The aim of the current study was to develop the Persian version of the CU-Q2oL with an acceptable reliability and validity.
Using the standard methods provided by guidelines, CU-Q2oL was translated into Persian. A total number of 110 patients with confirmed diagnosis of CU were asked to fill the questionnaire. Determination of scales was performed in addition to checking the data for internal consistency and known group validity. Urticaria activity score 7 (UAS-7) was used to assess the severity of the CU in the population study. The 6 dimensional scale of Persian CU-Q2oL was determined using the Exploratory Factor Analysis. About 68% of the variance was explained by these 6 factor structure higher than 59.9% of the original Italian version.
All 6 factors showed acceptable internal consistency as measured by Cronbach α coefficient. There was a significant correlation between UAS-7 and total CU-Q2oL score. UAS7 and the presence of angioedema were predictors of CU-Q2oL score.
The Persian version of CU-Q2oL was shown to be a valid and reliable tool to be used in the future clinical studies. Cultural considerations must be kept in mind in adoption of CU-Q2oL to other languages. |
| first_indexed | 2024-12-21T05:12:44Z |
| format | Article |
| id | doaj.art-5c2bba19218e4461b2d0ec530a055b27 |
| institution | Directory Open Access Journal |
| issn | 1735-1502 1735-5249 |
| language | English |
| last_indexed | 2024-12-21T05:12:44Z |
| publishDate | 2014-08-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Allergy, Asthma and Immunology |
| spelling | doaj.art-5c2bba19218e4461b2d0ec530a055b272022-12-21T19:15:00ZengTehran University of Medical SciencesIranian Journal of Allergy, Asthma and Immunology1735-15021735-52492014-08-01134410The Persian Version of the Chronic Urticaria Quality of Life Questionnaire: Factor Analysis, Validation, and Initial Clinical FindingsMarzieh Tavakol0Payam Mohammadinejad1Ilaria Baiardini2Fulvio Braido3Mohammad Gharagozlou4Asghar Aghamohammadi5Mohammad Nabavi6Abbas Dabbaghzade7Zahra Tavakol8Mohsen Afarideh9Nima Rezaei10Masoud Movahedi11Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.Allergy and Respiratory Diseases Clinic, DIMI, University of Genoa, IRCCS AOU San Martino-IST, Genova, Italy.Allergy and Respiratory Diseases Clinic, DIMI, University of Genoa, IRCCS AOU San Martino-IST, Genova, Italy.Department of Allergy and Clinical Immunology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.Department of Allergy and Clinical Immunology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran AND Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.Department of Allergy and Clinical Immunology, Rasool-e-Akram Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Allergy and Clinical Immunology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.Student ResearchCommittee,Kermanshah University of Medical Sciences, Kermanshah, Iran.Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran AND Molecular Immunology Research Center, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.Department of Allergy and Clinical Immunology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.Chronic urticaria (CU) also known as chronic idiopathic urticaria results in a lowered quality of life (QoL). Disease specific questionnaires are necessary to assess QoL in CU patients. Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL) is the only available and validated disease specific questionnaire in the assessment of QoL in CU patients originally developed in Italian language. The aim of the current study was to develop the Persian version of the CU-Q2oL with an acceptable reliability and validity. Using the standard methods provided by guidelines, CU-Q2oL was translated into Persian. A total number of 110 patients with confirmed diagnosis of CU were asked to fill the questionnaire. Determination of scales was performed in addition to checking the data for internal consistency and known group validity. Urticaria activity score 7 (UAS-7) was used to assess the severity of the CU in the population study. The 6 dimensional scale of Persian CU-Q2oL was determined using the Exploratory Factor Analysis. About 68% of the variance was explained by these 6 factor structure higher than 59.9% of the original Italian version. All 6 factors showed acceptable internal consistency as measured by Cronbach α coefficient. There was a significant correlation between UAS-7 and total CU-Q2oL score. UAS7 and the presence of angioedema were predictors of CU-Q2oL score. The Persian version of CU-Q2oL was shown to be a valid and reliable tool to be used in the future clinical studies. Cultural considerations must be kept in mind in adoption of CU-Q2oL to other languages.https://ijaai.tums.ac.ir/index.php/ijaai/article/view/445AdaptationChronic urticariaPersianQuality of lifeQuestionnaireValidation |
| spellingShingle | Marzieh Tavakol Payam Mohammadinejad Ilaria Baiardini Fulvio Braido Mohammad Gharagozlou Asghar Aghamohammadi Mohammad Nabavi Abbas Dabbaghzade Zahra Tavakol Mohsen Afarideh Nima Rezaei Masoud Movahedi The Persian Version of the Chronic Urticaria Quality of Life Questionnaire: Factor Analysis, Validation, and Initial Clinical Findings Iranian Journal of Allergy, Asthma and Immunology Adaptation Chronic urticaria Persian Quality of life Questionnaire Validation |
| title | The Persian Version of the Chronic Urticaria Quality of Life Questionnaire: Factor Analysis, Validation, and Initial Clinical Findings |
| title_full | The Persian Version of the Chronic Urticaria Quality of Life Questionnaire: Factor Analysis, Validation, and Initial Clinical Findings |
| title_fullStr | The Persian Version of the Chronic Urticaria Quality of Life Questionnaire: Factor Analysis, Validation, and Initial Clinical Findings |
| title_full_unstemmed | The Persian Version of the Chronic Urticaria Quality of Life Questionnaire: Factor Analysis, Validation, and Initial Clinical Findings |
| title_short | The Persian Version of the Chronic Urticaria Quality of Life Questionnaire: Factor Analysis, Validation, and Initial Clinical Findings |
| title_sort | persian version of the chronic urticaria quality of life questionnaire factor analysis validation and initial clinical findings |
| topic | Adaptation Chronic urticaria Persian Quality of life Questionnaire Validation |
| url | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/445 |
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