Influence of Hemofiltration on Intradialytic Plasma Volume Decrease
Background/Aims: Compared with hemodialysis (HD), hemodiafiltration (HDF) reduces the frequency of episodes of intradialytic hypotension. Intradialytic plasma volume decrease (IPVD) induced by ultrafiltration is a leading cause of the episodes, and hemofiltration might have a preventive effect on IP...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2019-02-01
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| Series: | Kidney & Blood Pressure Research |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/498839 |
| _version_ | 1819091784473509888 |
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| author | Masayuki Tanemoto Takeshi Tomita Yosuke Motoharu Masahiro Urata Yukio Okazaki |
| author_facet | Masayuki Tanemoto Takeshi Tomita Yosuke Motoharu Masahiro Urata Yukio Okazaki |
| author_sort | Masayuki Tanemoto |
| collection | DOAJ |
| description | Background/Aims: Compared with hemodialysis (HD), hemodiafiltration (HDF) reduces the frequency of episodes of intradialytic hypotension. Intradialytic plasma volume decrease (IPVD) induced by ultrafiltration is a leading cause of the episodes, and hemofiltration might have a preventive effect on IPVD. This study examined whether online HDF (ol-HDF) prevented IPVD compared with HD. Methods: Online HDF of pre-dilution mode (pre-ol-HDF) and post-dilution mode (post-ol-HDF) and HD were performed in 22 patients on maintenance dialysis. In each session, IPVD was calculated by using an intradialytic change in hematocrit, and IPVD in pre-ol-HDF and post-ol-HDF was compared with that in HD in a crossover manner. Results: While the ratios of intradialytic body weight loss to post-dialysis BW (IBWL/BW) in ol-HDF were generally smaller than those in HD, the levels of IPVD and IPVD/IBWL/BW were generally larger than those in HD; the IPVD levels were 0.108 ± 0.058, 0.113 ± 0.053, and 0.101 ± 0.057 (P = 0.67), and those of IPVD/IWL/BW were 2.21 ± 0.97, 2.32 ± 0.91, and 1.98 ± 1.14 (P = 0.21) in pre-ol-HDF, post-ol-HDF, and HD, respectively. Conclusion: Online mode hemofiltration, in either pre-dilution mode or post-dilution mode, performed in combination with hemodialysis has no preventive effect on IPVD. |
| first_indexed | 2024-12-21T22:45:14Z |
| format | Article |
| id | doaj.art-5c2f0bc72cd04b65af4db9f1771c9feb |
| institution | Directory Open Access Journal |
| issn | 1420-4096 1423-0143 |
| language | English |
| last_indexed | 2024-12-21T22:45:14Z |
| publishDate | 2019-02-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Kidney & Blood Pressure Research |
| spelling | doaj.art-5c2f0bc72cd04b65af4db9f1771c9feb2022-12-21T18:47:44ZengKarger PublishersKidney & Blood Pressure Research1420-40961423-01432019-02-01441889310.1159/000498839498839Influence of Hemofiltration on Intradialytic Plasma Volume DecreaseMasayuki TanemotoTakeshi TomitaYosuke MotoharuMasahiro UrataYukio OkazakiBackground/Aims: Compared with hemodialysis (HD), hemodiafiltration (HDF) reduces the frequency of episodes of intradialytic hypotension. Intradialytic plasma volume decrease (IPVD) induced by ultrafiltration is a leading cause of the episodes, and hemofiltration might have a preventive effect on IPVD. This study examined whether online HDF (ol-HDF) prevented IPVD compared with HD. Methods: Online HDF of pre-dilution mode (pre-ol-HDF) and post-dilution mode (post-ol-HDF) and HD were performed in 22 patients on maintenance dialysis. In each session, IPVD was calculated by using an intradialytic change in hematocrit, and IPVD in pre-ol-HDF and post-ol-HDF was compared with that in HD in a crossover manner. Results: While the ratios of intradialytic body weight loss to post-dialysis BW (IBWL/BW) in ol-HDF were generally smaller than those in HD, the levels of IPVD and IPVD/IBWL/BW were generally larger than those in HD; the IPVD levels were 0.108 ± 0.058, 0.113 ± 0.053, and 0.101 ± 0.057 (P = 0.67), and those of IPVD/IWL/BW were 2.21 ± 0.97, 2.32 ± 0.91, and 1.98 ± 1.14 (P = 0.21) in pre-ol-HDF, post-ol-HDF, and HD, respectively. Conclusion: Online mode hemofiltration, in either pre-dilution mode or post-dilution mode, performed in combination with hemodialysis has no preventive effect on IPVD.https://www.karger.com/Article/FullText/498839DialysisHemofiltrationHypotensionPlasma volume |
| spellingShingle | Masayuki Tanemoto Takeshi Tomita Yosuke Motoharu Masahiro Urata Yukio Okazaki Influence of Hemofiltration on Intradialytic Plasma Volume Decrease Kidney & Blood Pressure Research Dialysis Hemofiltration Hypotension Plasma volume |
| title | Influence of Hemofiltration on Intradialytic Plasma Volume Decrease |
| title_full | Influence of Hemofiltration on Intradialytic Plasma Volume Decrease |
| title_fullStr | Influence of Hemofiltration on Intradialytic Plasma Volume Decrease |
| title_full_unstemmed | Influence of Hemofiltration on Intradialytic Plasma Volume Decrease |
| title_short | Influence of Hemofiltration on Intradialytic Plasma Volume Decrease |
| title_sort | influence of hemofiltration on intradialytic plasma volume decrease |
| topic | Dialysis Hemofiltration Hypotension Plasma volume |
| url | https://www.karger.com/Article/FullText/498839 |
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