Effect of temperature on spiking patterns of neocortical layer 2/3 and layer 6 pyramidal neurons
The spiking patterns of neocortical pyramidal neurons are shaped by the conductances in their apical dendrites. We have previously shown that the spiking patterns of layer 5 pyramidal neurons change with temperature, probably because temperature modulates the electrical coupling between somatic and...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2012-05-01
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| Series: | Frontiers in Neural Circuits |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncir.2012.00028/full |
| _version_ | 1811315400783167488 |
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| author | Jack eWaters Tristan eHedrick |
| author_facet | Jack eWaters Tristan eHedrick |
| author_sort | Jack eWaters |
| collection | DOAJ |
| description | The spiking patterns of neocortical pyramidal neurons are shaped by the conductances in their apical dendrites. We have previously shown that the spiking patterns of layer 5 pyramidal neurons change with temperature, probably because temperature modulates the electrical coupling between somatic and dendritic compartments. Here we examine the effect of temperature on the spiking patterns of layer 2/3 and layer 6 pyramidal neurons in acute slices of mouse primary motor cortex. In both cell types, decreasing temperature led to more irregular spiking patterns. Our results indicate that a decrease in spiking regularity with decreasing temperature, probably mediated by increased electrical coupling between soma and dendrites, is common to all pyramidal neurons in motor cortex. |
| first_indexed | 2024-04-13T11:30:45Z |
| format | Article |
| id | doaj.art-5c31ba5b485340ed9305143162181cf7 |
| institution | Directory Open Access Journal |
| issn | 1662-5110 |
| language | English |
| last_indexed | 2024-04-13T11:30:45Z |
| publishDate | 2012-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neural Circuits |
| spelling | doaj.art-5c31ba5b485340ed9305143162181cf72022-12-22T02:48:35ZengFrontiers Media S.A.Frontiers in Neural Circuits1662-51102012-05-01610.3389/fncir.2012.0002822548Effect of temperature on spiking patterns of neocortical layer 2/3 and layer 6 pyramidal neuronsJack eWaters0Tristan eHedrick1Northwestern UniversityNorthwestern UniversityThe spiking patterns of neocortical pyramidal neurons are shaped by the conductances in their apical dendrites. We have previously shown that the spiking patterns of layer 5 pyramidal neurons change with temperature, probably because temperature modulates the electrical coupling between somatic and dendritic compartments. Here we examine the effect of temperature on the spiking patterns of layer 2/3 and layer 6 pyramidal neurons in acute slices of mouse primary motor cortex. In both cell types, decreasing temperature led to more irregular spiking patterns. Our results indicate that a decrease in spiking regularity with decreasing temperature, probably mediated by increased electrical coupling between soma and dendrites, is common to all pyramidal neurons in motor cortex.http://journal.frontiersin.org/Journal/10.3389/fncir.2012.00028/fullMotor CortexNeocortexDendritefiring patternelectrical coupling |
| spellingShingle | Jack eWaters Tristan eHedrick Effect of temperature on spiking patterns of neocortical layer 2/3 and layer 6 pyramidal neurons Frontiers in Neural Circuits Motor Cortex Neocortex Dendrite firing pattern electrical coupling |
| title | Effect of temperature on spiking patterns of neocortical layer 2/3 and layer 6 pyramidal neurons |
| title_full | Effect of temperature on spiking patterns of neocortical layer 2/3 and layer 6 pyramidal neurons |
| title_fullStr | Effect of temperature on spiking patterns of neocortical layer 2/3 and layer 6 pyramidal neurons |
| title_full_unstemmed | Effect of temperature on spiking patterns of neocortical layer 2/3 and layer 6 pyramidal neurons |
| title_short | Effect of temperature on spiking patterns of neocortical layer 2/3 and layer 6 pyramidal neurons |
| title_sort | effect of temperature on spiking patterns of neocortical layer 2 3 and layer 6 pyramidal neurons |
| topic | Motor Cortex Neocortex Dendrite firing pattern electrical coupling |
| url | http://journal.frontiersin.org/Journal/10.3389/fncir.2012.00028/full |
| work_keys_str_mv | AT jackewaters effectoftemperatureonspikingpatternsofneocorticallayer23andlayer6pyramidalneurons AT tristanehedrick effectoftemperatureonspikingpatternsofneocorticallayer23andlayer6pyramidalneurons |