Antioxidant activities from melanin pigment produced by marine actinobacterium of Streptomyces species

Melanin is macromolecules which have been developed while oxidative polymerization of phenolic compounds. It has been found that the majority of marine organisms produce melanin pigment. To obtain the melanin from marine actinobacteria and their biological properties are studied. Isolation and ident...

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Main Authors: M I Sheefaa, Pitchiah Sivaperumal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2022;volume=13;issue=5;spage=84;epage=87;aulast=Sheefaa
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author M I Sheefaa
Pitchiah Sivaperumal
author_facet M I Sheefaa
Pitchiah Sivaperumal
author_sort M I Sheefaa
collection DOAJ
description Melanin is macromolecules which have been developed while oxidative polymerization of phenolic compounds. It has been found that the majority of marine organisms produce melanin pigment. To obtain the melanin from marine actinobacteria and their biological properties are studied. Isolation and identification of marine actinobacteria were carried out using the media of ISP-1, ISP-7. Spore chain morphology, chemotaxonomic characteristics were also analyzed by the International Streptomyces Project. The antioxidant activities of DPPH, lipid peroxide using actinobacterial melanin were determined. The Streptomyces species have the capacity to produce melanin pigments and it shows potential antioxidant properties. When DPPH concentrations were compared with the ascorbic acid standard, the melanin of 150 μg/ml showed 93.47% of scavenging. The present study was concluded that melanin pigment obtained from marine actinobacterium of Streptomyces species has potential antioxidant activities and these components might be useful to pharmaceutical industries.
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spelling doaj.art-5c31c8037d4448538e4caeca7a5b96292022-12-22T04:23:01ZengWolters Kluwer Medknow PublicationsJournal of Advanced Pharmaceutical Technology & Research2231-40400976-20942022-01-01135848710.4103/japtr.japtr_338_22Antioxidant activities from melanin pigment produced by marine actinobacterium of Streptomyces speciesM I SheefaaPitchiah SivaperumalMelanin is macromolecules which have been developed while oxidative polymerization of phenolic compounds. It has been found that the majority of marine organisms produce melanin pigment. To obtain the melanin from marine actinobacteria and their biological properties are studied. Isolation and identification of marine actinobacteria were carried out using the media of ISP-1, ISP-7. Spore chain morphology, chemotaxonomic characteristics were also analyzed by the International Streptomyces Project. The antioxidant activities of DPPH, lipid peroxide using actinobacterial melanin were determined. The Streptomyces species have the capacity to produce melanin pigments and it shows potential antioxidant properties. When DPPH concentrations were compared with the ascorbic acid standard, the melanin of 150 μg/ml showed 93.47% of scavenging. The present study was concluded that melanin pigment obtained from marine actinobacterium of Streptomyces species has potential antioxidant activities and these components might be useful to pharmaceutical industries.http://www.japtr.org/article.asp?issn=2231-4040;year=2022;volume=13;issue=5;spage=84;epage=87;aulast=Sheefaaantioxidantdppheco-friendlygreen synthesismarine actinobacteriamelaninstreptomyces sp.
spellingShingle M I Sheefaa
Pitchiah Sivaperumal
Antioxidant activities from melanin pigment produced by marine actinobacterium of Streptomyces species
Journal of Advanced Pharmaceutical Technology & Research
antioxidant
dpph
eco-friendly
green synthesis
marine actinobacteria
melanin
streptomyces sp.
title Antioxidant activities from melanin pigment produced by marine actinobacterium of Streptomyces species
title_full Antioxidant activities from melanin pigment produced by marine actinobacterium of Streptomyces species
title_fullStr Antioxidant activities from melanin pigment produced by marine actinobacterium of Streptomyces species
title_full_unstemmed Antioxidant activities from melanin pigment produced by marine actinobacterium of Streptomyces species
title_short Antioxidant activities from melanin pigment produced by marine actinobacterium of Streptomyces species
title_sort antioxidant activities from melanin pigment produced by marine actinobacterium of streptomyces species
topic antioxidant
dpph
eco-friendly
green synthesis
marine actinobacteria
melanin
streptomyces sp.
url http://www.japtr.org/article.asp?issn=2231-4040;year=2022;volume=13;issue=5;spage=84;epage=87;aulast=Sheefaa
work_keys_str_mv AT misheefaa antioxidantactivitiesfrommelaninpigmentproducedbymarineactinobacteriumofstreptomycesspecies
AT pitchiahsivaperumal antioxidantactivitiesfrommelaninpigmentproducedbymarineactinobacteriumofstreptomycesspecies