DNA Methylation of PI3K/AKT Pathway-Related Genes Predicts Outcome in Patients with Pancreatic Cancer: A Comprehensive Bioinformatics-Based Study

DNA Methylation of PI3K/AKT Pathway-Related Genes Predicts Outcome in Patients with Pancreatic Cancer: A Comprehensive Bioinformatics-Based Study

Pancreatic cancer (PCA) is one of the most lethal malignancies worldwide with a 5-year survival rate of 9%. Despite the advances in the field, the need for an earlier detection and effective therapies is paramount. PCA high heterogeneity suggests that epigenetic alterations play a key role in tumour...

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Bibliographic Details
Main Authors: Inês Faleiro, Vânia Palma Roberto, Secil Demirkol Canli, Nicolas A. Fraunhoffer, Juan Iovanna, Ali Osmay Gure, Wolfgang Link, Pedro Castelo-Branco
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
pancreatic cancer
epigenetics
DNA methylation
PI3K/AKT pathway
Online Access:https://www.mdpi.com/2072-6694/13/24/6354

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