Inhibition of Skin Inflammation by Scytonemin, an Ultraviolet Sunscreen Pigment

Inhibition of Skin Inflammation by Scytonemin, an Ultraviolet Sunscreen Pigment

Scytonemin is a yellow-green ultraviolet sunscreen pigment present in different genera of aquatic and terrestrial blue-green algae, including marine cyanobacteria. In the present study, the anti-inflammatory activities of scytonemin were evaluated in vitro and in vivo. Topical application of scytone...

Full description

Bibliographic Details
Main Authors:	Moo Rim Kang, Sun Ah Jo, Hyunju Lee, Yeo Dae Yoon, Joo-Hee Kwon, Jeong-Wook Yang, Byeong Jo Choi, Ki Hwan Park, Myeong Youl Lee, Chang Woo Lee, Kyeong-Ryoon Lee, Jong Soon Kang
Format:	Article
Language:	English
Published:	MDPI AG 2020-06-01
Series:	Marine Drugs
Subjects:	scytonemin skin inflammation tumor necrosis factor-α nitric oxide NF-κB
Online Access:	https://www.mdpi.com/1660-3397/18/6/300

Similar Items

Biotechnological Production of the Sunscreen Pigment Scytonemin in Cyanobacteria: Progress and Strategy
by: Xiang Gao, et al.
Published: (2021-02-01)

Mutational studies of putative biosynthetic genes for the cyanobacterial sunscreen scytonemin in Nostoc punctiforme ATCC 29133
by: Daniela eFerreira, et al.
Published: (2016-05-01)

Expression of Scytonemin Biosynthesis Genes under Alternative Stress Conditions in the Cyanobacterium <i>Nostoc punctiforme</i>
by: Janine Bennett, et al.
Published: (2022-02-01)

Complementary UV-Absorption of Mycosporine-like Amino Acids and Scytonemin is Responsible for the UV-Insensitivity of Photosynthesis in Nostoc flagelliforme
by: Donat-Peter Häder, et al.
Published: (2010-01-01)

UV-A Irradiation Increases Scytonemin Biosynthesis in Cyanobacteria Inhabiting Halites at Salar Grande, Atacama Desert
by: Gabriela Orellana, et al.
Published: (2020-10-01)

Probing a Coral Genome for Components of the Photoprotective Scytonemin Biosynthetic Pathway and the 2-Aminoethylphosphonate Pathway
by: Nori Satoh, et al.
Published: (2013-02-01)

Response of Endolithic Chroococcidiopsis Strains From the Polyextreme Atacama Desert to Light Radiation
by: María Cristina Casero, et al.
Published: (2021-01-01)

Protection against Lipopolysaccharide-Induced Endotoxemia by Terrein Is Mediated by Blocking Interleukin-1β and Interleukin-6 Production
by: Yeo Dae Yoon, et al.
Published: (2022-11-01)

A comparative genomics approach to understanding the biosynthesis of the sunscreen scytonemin in cyanobacteria
by: Potrafka Ruth M, et al.
Published: (2009-07-01)

Microalgae Photo-Protectants and Related Bio-Carriers Loaded with Bioactive Entities for Skin Applications—An Insight of Microalgae Biotechnology
by: Berenice Santiesteban-Romero, et al.
Published: (2022-07-01)

The role of the protective shield against UV-C radiation and its molecular interactions in Nostoc species (Cyanobacteria)
by: Pardis Irankhahi, et al.
Published: (2024-08-01)

Adaptation strategies of endolithic chlorophototrophs to survive the hyperarid and extreme solar radiation environment of the Atacama Desert
by: Jacek eWierzchos, et al.
Published: (2015-09-01)

(3<i>β</i>,16<i>α</i>)-3,16-Dihydroxypregn-5-en-20-one from the Twigs of <i>Euonymus alatus</i> (Thunb.) Sieb. Exerts Anti-Inflammatory Effects in LPS-Stimulated RAW-264.7 Macrophages
by: Seulah Lee, et al.
Published: (2019-10-01)

Cyanobacteria and Red Macroalgae as Potential Sources of Antioxidants and UV Radiation-Absorbing Compounds for Cosmeceutical Applications
by: Julia Vega, et al.
Published: (2020-12-01)

Prenylated Polyphenols from Broussonetia kazinoki as Inhibitors of Nitric Oxide Production
by: Da Yeon Lee, et al.
Published: (2018-03-01)

Discovery of Novel Tyrosinase Inhibitors From Marine Cyanobacteria
by: Yifan He, et al.
Published: (2022-07-01)

Photoprotective effects of sphingomyelin-containing milk phospholipids in ultraviolet B–irradiated hairless mice by suppressing nuclear factor-κB expression
by: Yejin Ahn, et al.
Published: (2022-03-01)

Anti-inflammatory effect of torilidis fructus ethanol extract through inhibition of Src
by: Gyubyung Park, et al.
Published: (2017-01-01)

Protein disulfide isomerase-mediated S-nitrosylation facilitates surface expression of P2X7 receptor following status epilepticus
by: Duk-Shin Lee, et al.
Published: (2021-01-01)

Nitric Oxide in Gentamicin-induced Acute Tubular Necrosis in Rats
by: Emina Nakaš-Ićindić, et al.
Published: (2005-05-01)

The Effects of Inducible Nitric Oxide Synthase Inhibitor L-N6-(1-Iminoethyl) Lysine in Gentamicin-Induced Acute Tubular Necrosis in Rats
by: Nesina Avdagić, et al.
Published: (2007-11-01)

Autologous Fat Graft in the Reconstructed Breast: Fat Absorption Rate and Safety based on Sonographic Identification
by: Hong Youl Kim, et al.
Published: (2014-11-01)

Effectiveness of Nivea Sunscreen under Ultraviolet Light
by: Piset Virachunya, et al.
Published: (2008-01-01)

Agelasine D Suppresses RANKL-Induced Osteoclastogenesis via Down-Regulation of c-Fos, NFATc1 and NF-κB
by: Moo Rim Kang, et al.
Published: (2014-11-01)

NO-dependent protective effect of VEGF against excitotoxicity on layer VI of the developing cerebral cortex
by: Faiza El Ghazi, et al.
Published: (2012-03-01)

Anti-inflammatory effects of a traditional Korean medicine: Ojayeonjonghwan
by: Sun-Young Nam, et al.
Published: (2017-01-01)

Exogenous, but not Endogenous Nitric Oxide Inhibits Adhesion Molecule Expression in Human Endothelial Cells
by: Jin eQian, et al.
Published: (2012-01-01)

New Insights into the Pivotal Role of Iron/Heme Metabolism in TLR4/NF-κB Signaling-Mediated Inflammatory Responses in Human Monocytes
by: Dong Young Kang, et al.
Published: (2021-09-01)

Effect of salinity on scytonemin yield in endolithic cyanobacteria from the Atacama Desert
by: María Cristina Casero, et al.
Published: (2024-04-01)

MCP-1 and MIP-3α Secreted from Necrotic Cell-Treated Glioblastoma Cells Promote Migration/Infiltration of Microglia
by: Yieun Jung, et al.
Published: (2018-07-01)

Ultraviolet-Protective Clothing and Sunscreen: Sun-Protection for Healthy Skin
by: Daria Sieniawska, et al.
Published: (2024-05-01)

Pharmacological activity and quantitative analysis of flavonoids isolated from the flowers of Begonia semperflorens Link et Otto
by: Jung-Hwa Kwon, et al.
Published: (2019-03-01)

Jeju seaweeds suppress lipopolysaccharide-stimulated proinflammatory response in RAW 264.7 murine macrophages
by: Eun-Jin Yang, et al.
Published: (2014-07-01)

Inhibitory effect of fucoidan on TNF-α-induced inflammation in human retinal pigment epithelium cells
by: Sol Lee, et al.
Published: (2023-04-01)

Expression and Distribution of Free Zinc in Penile Erectile Tissue
by: Beom Seok Kang, et al.
Published: (2023-01-01)

Antidesma thwaitesianum Müll. Arg. fruit extract rich in 5-hydroxymethylfurfural exhibits anti-inflammatory effects in lipopolysaccharide-stimulated RAW264.7 macrophages
by: Orapin Insuan, et al.
Published: (2022-04-01)

The anti-inflammatory effect of Sonchus oleraceus aqueous extract on lipopolysaccharide stimulated RAW 264.7 cells and mice
by: Qi Li, et al.
Published: (2017-01-01)

Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-κB and iNOS signaling pathways
by: Chuanhong Wu, et al.
Published: (2015-07-01)

Spirulina Platensis Protects Against Renal Injury in Rats with Gentamicin-Induced Acute Tubular Necrosis
by: Nesina Avdagić, et al.
Published: (2008-11-01)

A selective toxicity of Pt-coated Au nanoparticles in cancerous MCF-7 cells over non-cancerous HUVE cells
by: Mohd Javed Akhtar, et al.
Published: (2023-04-01)