Comparative analysis of the secretory capacity of islets of langerhans cultured with biopolymer-based collagen-containing hydrogel and tissue-specific matrix

Comparative analysis of the secretory capacity of islets of langerhans cultured with biopolymer-based collagen-containing hydrogel and tissue-specific matrix

Introduction. Creation of a biomedical cell product – a bioengineered pancreatic construct – is hampered by problems associated with maintaining the viability of functionally active isolated islets of Langerhans (ILs). Both biopolymer and tissue-specific scaffolds can contribute to maintaining the s...

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Bibliographic Details
Main Authors: N. V. Baranova, L. A. Kirsanova, A. S. Ponomareva, E. A. Nemets, Y. B. Basok, G. N. Bubentsova, V. A. Surguchenko, V. I. Sevastianov
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2020-02-01
Series:Вестник трансплантологии и искусственных органов
Subjects:
islets of langerhans
biopolymer‑based hydrogel
decellularized pancreas
matrix scaffold
cultivation
insulin secretion
Online Access:https://journal.transpl.ru/vtio/article/view/1107

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