KCa3.1 Inhibition Decreases Size and Alters Composition of Atherosclerotic Lesions Induced by Low, Oscillatory Flow

Low, oscillatory flow/shear patterns are associated with atherosclerotic lesion development. Increased expression of KCa3.1 has been found in Vascular Smooth Muscle (VSM), macrophages and T-cells in lesions from humans and mice. Increased expression of KCa3.1, is also required for VSM cell prolifera...

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Bibliographic Details
Main Authors: Darla L. Tharp, Douglas K. Bowles
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Artery Research
Subjects:
Online Access:https://www.atlantis-press.com/article/125952714/view

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