Enhanced Hippocampus-Nidopallium Caudolaterale Connectivity during Route Formation in Goal-Directed Spatial Learning of Pigeons
Goal-directed spatial learning is crucial for the survival of animals, in which the formation of the route from the current location to the goal is one of the central problems. A distributed brain network comprising the hippocampus and prefrontal cortex has been shown to support such capacity, yet i...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/11/7/2003 |
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| author | Meng-Meng Li Jian-Tao Fan Shu-Guan Cheng Li-Fang Yang Long Yang Liao-Feng Wang Zhi-Gang Shang Hong Wan |
| author_facet | Meng-Meng Li Jian-Tao Fan Shu-Guan Cheng Li-Fang Yang Long Yang Liao-Feng Wang Zhi-Gang Shang Hong Wan |
| author_sort | Meng-Meng Li |
| collection | DOAJ |
| description | Goal-directed spatial learning is crucial for the survival of animals, in which the formation of the route from the current location to the goal is one of the central problems. A distributed brain network comprising the hippocampus and prefrontal cortex has been shown to support such capacity, yet it is not fully understood how the most similar brain regions in birds, the hippocampus (Hp) and nidopallium caudolaterale (NCL), cooperate during route formation in goal-directed spatial learning. Hence, we examined neural activity in the Hp-NCL network of pigeons and explored the connectivity dynamics during route formation in a goal-directed spatial task. We found that behavioral changes in spatial learning during route formation are accompanied by modifications in neural patterns in the Hp-NCL network. Specifically, as pigeons learned to solve the task, the spectral power in both regions gradually decreased. Meanwhile, elevated hippocampal theta (5 to 12 Hz) connectivity and depressed connectivity in NCL were also observed. Lastly, the interregional functional connectivity was found to increase with learning, specifically in the theta frequency band during route formation. These results provide insight into the dynamics of the Hp-NCL network during spatial learning, serving to reveal the potential mechanism of avian spatial navigation. |
| first_indexed | 2024-03-10T09:47:53Z |
| format | Article |
| id | doaj.art-5c3e06817b17450397ad4b3d3224d8f3 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T09:47:53Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-5c3e06817b17450397ad4b3d3224d8f32023-11-22T03:00:08ZengMDPI AGAnimals2076-26152021-07-01117200310.3390/ani11072003Enhanced Hippocampus-Nidopallium Caudolaterale Connectivity during Route Formation in Goal-Directed Spatial Learning of PigeonsMeng-Meng Li0Jian-Tao Fan1Shu-Guan Cheng2Li-Fang Yang3Long Yang4Liao-Feng Wang5Zhi-Gang Shang6Hong Wan7School of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, ChinaSchool of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, ChinaSchool of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, ChinaSchool of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, ChinaSchool of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, ChinaSchool of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, ChinaSchool of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, ChinaSchool of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, ChinaGoal-directed spatial learning is crucial for the survival of animals, in which the formation of the route from the current location to the goal is one of the central problems. A distributed brain network comprising the hippocampus and prefrontal cortex has been shown to support such capacity, yet it is not fully understood how the most similar brain regions in birds, the hippocampus (Hp) and nidopallium caudolaterale (NCL), cooperate during route formation in goal-directed spatial learning. Hence, we examined neural activity in the Hp-NCL network of pigeons and explored the connectivity dynamics during route formation in a goal-directed spatial task. We found that behavioral changes in spatial learning during route formation are accompanied by modifications in neural patterns in the Hp-NCL network. Specifically, as pigeons learned to solve the task, the spectral power in both regions gradually decreased. Meanwhile, elevated hippocampal theta (5 to 12 Hz) connectivity and depressed connectivity in NCL were also observed. Lastly, the interregional functional connectivity was found to increase with learning, specifically in the theta frequency band during route formation. These results provide insight into the dynamics of the Hp-NCL network during spatial learning, serving to reveal the potential mechanism of avian spatial navigation.https://www.mdpi.com/2076-2615/11/7/2003hippocampusnidopallium caudolateraleroute formationgoal-directed spatial learningfunctional connectivitypigeon |
| spellingShingle | Meng-Meng Li Jian-Tao Fan Shu-Guan Cheng Li-Fang Yang Long Yang Liao-Feng Wang Zhi-Gang Shang Hong Wan Enhanced Hippocampus-Nidopallium Caudolaterale Connectivity during Route Formation in Goal-Directed Spatial Learning of Pigeons Animals hippocampus nidopallium caudolaterale route formation goal-directed spatial learning functional connectivity pigeon |
| title | Enhanced Hippocampus-Nidopallium Caudolaterale Connectivity during Route Formation in Goal-Directed Spatial Learning of Pigeons |
| title_full | Enhanced Hippocampus-Nidopallium Caudolaterale Connectivity during Route Formation in Goal-Directed Spatial Learning of Pigeons |
| title_fullStr | Enhanced Hippocampus-Nidopallium Caudolaterale Connectivity during Route Formation in Goal-Directed Spatial Learning of Pigeons |
| title_full_unstemmed | Enhanced Hippocampus-Nidopallium Caudolaterale Connectivity during Route Formation in Goal-Directed Spatial Learning of Pigeons |
| title_short | Enhanced Hippocampus-Nidopallium Caudolaterale Connectivity during Route Formation in Goal-Directed Spatial Learning of Pigeons |
| title_sort | enhanced hippocampus nidopallium caudolaterale connectivity during route formation in goal directed spatial learning of pigeons |
| topic | hippocampus nidopallium caudolaterale route formation goal-directed spatial learning functional connectivity pigeon |
| url | https://www.mdpi.com/2076-2615/11/7/2003 |
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