Effect of Echocardiographic Epicardial Adipose Tissue Thickness on Success Rates of Premature Ventricular Contraction Ablation
Background: Idiopathic premature ventricular contractions are frequently detected ventricular arrhythmias, and radiofrequency ablation is an effectively treatment for improving symptoms and eliminating premature ventricular contractions. Studies have reported a relationship between an elevated epica...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2019-11-01
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| Series: | Balkan Medical Journal |
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| Online Access: | http://balkanmedicaljournal.org/text.php?lang=en&id=2130 |
| _version_ | 1797923608906956800 |
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| author | Selçuk Kanat Bilge Duran Karaduman Ahmet Tütüncü Erhan Tenekecioğlu Ferit Onur Mutluer Nihal Akar Bayram |
| author_facet | Selçuk Kanat Bilge Duran Karaduman Ahmet Tütüncü Erhan Tenekecioğlu Ferit Onur Mutluer Nihal Akar Bayram |
| author_sort | Selçuk Kanat |
| collection | DOAJ |
| description | Background: Idiopathic premature ventricular contractions are frequently detected ventricular arrhythmias, and radiofrequency ablation is an effectively treatment for improving symptoms and eliminating premature ventricular contractions. Studies have reported a relationship between an elevated epicardial adipose tissue thickness and myocardial structural pathologies. However, the association between epicardial adipose tissue thickness and success rates of premature ventricular contraction ablation has not yet been investigated.
Aims: To assess the relationship between epicardial adipose tissue thickness and success rates of premature ventricular contraction ablation.
Study Design: Retrospective case-control study.
Methods: This study enrolled a total of 106 consecutive patients who have had a high premature ventricular contraction burden of >10,000/24-h assessed using ambulatory Holter monitorization and underwent catheter ablation. A frequency of premature ventricular contractions of more than 10,000/day was defined as frequent premature ventricular contraction. Epicardial adipose tissue thickness was measured using 2D transthoracic echocardiography. A successful ablation was defined as >80% decrease in pre-procedural premature ventricular contraction attacks with the same morphology during 24-h Holter monitorization after a 1-month follow-up visit from an ablation procedure.
Results: Successful premature ventricular contraction ablation was achieved in 87 (82.1%) patients. Epicardial adipose tissue thickness was significantly higher in patients with unsuccessful ablation (p<0.001). Procedure time, total fluoroscopy time, and radiofrequency ablation time were statistically higher in the unsuccessful group (p<0.001). Stepwise multivariate logistic regression analysis showed that epicardial adipose tissue thickness and pseudo-delta wave time were independently associated with procedural success (both p values <0.001). In the receiver-operating curve analysis, epicardial adipose tissue thickness was found to be an important predictor for procedural success (area under the receiver-operating characteristic curve= 0.85, p=0.001), with a cutoff value of 7.7 mm, a sensitivity of 92%, and a specificity of 68%.
Conclusion: Epicardial adipose tissue thickness is higher in patients with premature ventricular contraction ablation failure, which may be indicative of procedural success. |
| first_indexed | 2024-04-10T14:50:09Z |
| format | Article |
| id | doaj.art-5c3ed90aea0b438cb7e1eed739d1ebf1 |
| institution | Directory Open Access Journal |
| issn | 2146-3123 2146-3131 |
| language | English |
| last_indexed | 2024-04-10T14:50:09Z |
| publishDate | 2019-11-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Balkan Medical Journal |
| spelling | doaj.art-5c3ed90aea0b438cb7e1eed739d1ebf12023-02-15T16:07:39ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312019-11-0136632433010.4274/balkanmedj.galenos.2019.2019.4.88Effect of Echocardiographic Epicardial Adipose Tissue Thickness on Success Rates of Premature Ventricular Contraction AblationSelçuk Kanat0Bilge Duran Karaduman1Ahmet Tütüncü2Erhan Tenekecioğlu3Ferit Onur Mutluer4Nihal Akar Bayram5Clinic of Cardiology, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, TurkeyClinic of Cardiology, Ankara Atatürk Training and Research Hospital, Ankara, TurkeyClinic of Cardiology, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, TurkeyClinic of Cardiology, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, TurkeyDepartment of Cardiology, Koç University Hospital, İstanbul, TurkeyDepartment of Cardiology, Yıldırım Beyazıt University School of Medicine, Ankara, TurkeyBackground: Idiopathic premature ventricular contractions are frequently detected ventricular arrhythmias, and radiofrequency ablation is an effectively treatment for improving symptoms and eliminating premature ventricular contractions. Studies have reported a relationship between an elevated epicardial adipose tissue thickness and myocardial structural pathologies. However, the association between epicardial adipose tissue thickness and success rates of premature ventricular contraction ablation has not yet been investigated. Aims: To assess the relationship between epicardial adipose tissue thickness and success rates of premature ventricular contraction ablation. Study Design: Retrospective case-control study. Methods: This study enrolled a total of 106 consecutive patients who have had a high premature ventricular contraction burden of >10,000/24-h assessed using ambulatory Holter monitorization and underwent catheter ablation. A frequency of premature ventricular contractions of more than 10,000/day was defined as frequent premature ventricular contraction. Epicardial adipose tissue thickness was measured using 2D transthoracic echocardiography. A successful ablation was defined as >80% decrease in pre-procedural premature ventricular contraction attacks with the same morphology during 24-h Holter monitorization after a 1-month follow-up visit from an ablation procedure. Results: Successful premature ventricular contraction ablation was achieved in 87 (82.1%) patients. Epicardial adipose tissue thickness was significantly higher in patients with unsuccessful ablation (p<0.001). Procedure time, total fluoroscopy time, and radiofrequency ablation time were statistically higher in the unsuccessful group (p<0.001). Stepwise multivariate logistic regression analysis showed that epicardial adipose tissue thickness and pseudo-delta wave time were independently associated with procedural success (both p values <0.001). In the receiver-operating curve analysis, epicardial adipose tissue thickness was found to be an important predictor for procedural success (area under the receiver-operating characteristic curve= 0.85, p=0.001), with a cutoff value of 7.7 mm, a sensitivity of 92%, and a specificity of 68%. Conclusion: Epicardial adipose tissue thickness is higher in patients with premature ventricular contraction ablation failure, which may be indicative of procedural success.http://balkanmedicaljournal.org/text.php?lang=en&id=2130ablationepicardial adipose tissueprematureventricular complex |
| spellingShingle | Selçuk Kanat Bilge Duran Karaduman Ahmet Tütüncü Erhan Tenekecioğlu Ferit Onur Mutluer Nihal Akar Bayram Effect of Echocardiographic Epicardial Adipose Tissue Thickness on Success Rates of Premature Ventricular Contraction Ablation Balkan Medical Journal ablation epicardial adipose tissue premature ventricular complex |
| title | Effect of Echocardiographic Epicardial Adipose Tissue Thickness on Success Rates of Premature Ventricular Contraction Ablation |
| title_full | Effect of Echocardiographic Epicardial Adipose Tissue Thickness on Success Rates of Premature Ventricular Contraction Ablation |
| title_fullStr | Effect of Echocardiographic Epicardial Adipose Tissue Thickness on Success Rates of Premature Ventricular Contraction Ablation |
| title_full_unstemmed | Effect of Echocardiographic Epicardial Adipose Tissue Thickness on Success Rates of Premature Ventricular Contraction Ablation |
| title_short | Effect of Echocardiographic Epicardial Adipose Tissue Thickness on Success Rates of Premature Ventricular Contraction Ablation |
| title_sort | effect of echocardiographic epicardial adipose tissue thickness on success rates of premature ventricular contraction ablation |
| topic | ablation epicardial adipose tissue premature ventricular complex |
| url | http://balkanmedicaljournal.org/text.php?lang=en&id=2130 |
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