Phase-contrast X-ray microtomography of mouse fetus
Summary A phase-contrast X-ray microtomography system using the Talbot imaging has been built at the SPring-8 synchrotron radiation facility. This system has much higher density resolution than absorption-based X-ray microtomography. The tomographic sections of formalin-fixed mouse fetuses obtained...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
The Company of Biologists
2012-02-01
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| Series: | Biology Open |
| Subjects: | |
| Online Access: | http://bio.biologists.org/content/1/3/269 |
| _version_ | 1818669505423867904 |
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| author | Masato Hoshino Kentaro Uesugi Naoto Yagi |
| author_facet | Masato Hoshino Kentaro Uesugi Naoto Yagi |
| author_sort | Masato Hoshino |
| collection | DOAJ |
| description | Summary
A phase-contrast X-ray microtomography system using the Talbot imaging has been built at the SPring-8 synchrotron radiation facility. This system has much higher density resolution than absorption-based X-ray microtomography. The tomographic sections of formalin-fixed mouse fetuses obtained with this method clearly depict various organs without any staining at a pixel resolution of up to 5 µm. Since this technique allows us to obtain three-dimensional structural information without sectioning, it will be particularly useful to examine anomalies that take place during development. It can be also used to quantitatively measure volume and mass of organs during development. |
| first_indexed | 2024-12-17T06:53:17Z |
| format | Article |
| id | doaj.art-5c3ee482404e4bbcb034a0d0ecd500e8 |
| institution | Directory Open Access Journal |
| issn | 2046-6390 |
| language | English |
| last_indexed | 2024-12-17T06:53:17Z |
| publishDate | 2012-02-01 |
| publisher | The Company of Biologists |
| record_format | Article |
| series | Biology Open |
| spelling | doaj.art-5c3ee482404e4bbcb034a0d0ecd500e82022-12-21T21:59:32ZengThe Company of BiologistsBiology Open2046-63902012-02-011326927410.1242/bio.20124302012430Phase-contrast X-ray microtomography of mouse fetusMasato HoshinoKentaro UesugiNaoto YagiSummary A phase-contrast X-ray microtomography system using the Talbot imaging has been built at the SPring-8 synchrotron radiation facility. This system has much higher density resolution than absorption-based X-ray microtomography. The tomographic sections of formalin-fixed mouse fetuses obtained with this method clearly depict various organs without any staining at a pixel resolution of up to 5 µm. Since this technique allows us to obtain three-dimensional structural information without sectioning, it will be particularly useful to examine anomalies that take place during development. It can be also used to quantitatively measure volume and mass of organs during development.http://bio.biologists.org/content/1/3/269Phase-contrastX-ray CTFetus |
| spellingShingle | Masato Hoshino Kentaro Uesugi Naoto Yagi Phase-contrast X-ray microtomography of mouse fetus Biology Open Phase-contrast X-ray CT Fetus |
| title | Phase-contrast X-ray microtomography of mouse fetus |
| title_full | Phase-contrast X-ray microtomography of mouse fetus |
| title_fullStr | Phase-contrast X-ray microtomography of mouse fetus |
| title_full_unstemmed | Phase-contrast X-ray microtomography of mouse fetus |
| title_short | Phase-contrast X-ray microtomography of mouse fetus |
| title_sort | phase contrast x ray microtomography of mouse fetus |
| topic | Phase-contrast X-ray CT Fetus |
| url | http://bio.biologists.org/content/1/3/269 |
| work_keys_str_mv | AT masatohoshino phasecontrastxraymicrotomographyofmousefetus AT kentarouesugi phasecontrastxraymicrotomographyofmousefetus AT naotoyagi phasecontrastxraymicrotomographyofmousefetus |