Methyl gallate isolated from Mangifera pajang kernel induces proliferation inhibition and apoptosis in MCF-7 breast cancer cells via oxidative stress

Methyl gallate isolated from Mangifera pajang kernel induces proliferation inhibition and apoptosis in MCF-7 breast cancer cells via oxidative stress

Objective: To determine the lead bioactive compound in kernel extract of Mangifera pajang and its anti-cancer activity against human breast cancer cell lines with positive estrogen receptor (MCF-7). Methods: The methanolic extract of dried powder kernel of Mangifera pajang was exposed to column chro...

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Bibliographic Details
Main Authors: Ranneh Yazan, Abu Bakar Mohd Fadzelly, Rahim Azlen-Che, Kassim Nur Kartinee, Stanslas Johnson, Teh Yuan-Han, Fadel Abdulmannan, S Ellulu Mohammed
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
mangifera pajang; methyl gallate; breast cancer; cell cycle; apoptosis; oxidative stress
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2022;volume=12;issue=4;spage=175;epage=184;aulast=Yazan

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