Cellular senescence in skeletal disease: mechanisms and treatment

Cellular senescence in skeletal disease: mechanisms and treatment

Abstract The musculoskeletal system supports the movement of the entire body and provides blood production while acting as an endocrine organ. With aging, the balance of bone homeostasis is disrupted, leading to bone loss and degenerative diseases, such as osteoporosis, osteoarthritis, and intervert...

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Bibliographic Details
Main Authors: Xu He, Wei Hu, Yuanshu Zhang, Mimi Chen, Yicheng Ding, Huilin Yang, Fan He, Qiaoli Gu, Qin Shi
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cellular & Molecular Biology Letters
Subjects:
Cellular senescence
Chronic inflammation
Age-related orthopaedic diseases
Signalling pathways
Bone marrow
Online Access:https://doi.org/10.1186/s11658-023-00501-5

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