Circulating Cell-Free DNA-Based Methylation Pattern in Saliva for Early Diagnosis of Head and Neck Cancer

Circulating Cell-Free DNA-Based Methylation Pattern in Saliva for Early Diagnosis of Head and Neck Cancer

Head and neck cancer (HNC) remains one of the leading causes of mortality worldwide due to tumor diagnosis at a late stage, loco-regional aggression, and distant metastases. A standardized diagnostic procedure for HNC is a tissue biopsy that cannot faithfully portray the in-depth tumor dynamics. The...

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Bibliographic Details
Main Authors: Natalia Birknerova, Veronika Mancikova, Evan David Paul, Jan Matyasovsky, Pavol Cekan, Vladimir Palicka, Helena Parova
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cancers
Subjects:
biomarker
cell-free DNA (cfDNA)
circulating tumor DNA (ctDNA)
DNA methylation
early cancer detection
head and neck cancer
Online Access:https://www.mdpi.com/2072-6694/14/19/4882

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