Correlation of Autoantibodies Presence Detected By IFA-anti-dsDNA, IFA-AMA and Immunoblotting with Corresponding Data in Clinical Management of Autoimmune Diseases
Diagnosis and management of patients with SLE (Systemic Lupus Eritematosus), autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), involves specific diagnostic tests, such as IFA-AMA, IFA anti-dsDNA and immunoblotting for the detection of autoantibodies for specific autoantigens (mitochondria...
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| Format: | Article |
| Language: | English |
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2008-02-01
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| Series: | Biomolecules & Biomedicine |
| Subjects: | |
| Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3004 |
| _version_ | 1797260821450981376 |
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| author | Đemo Subašić Jasenko Karamehić Farid Ljuca Faris Gavrankapetanović Marina Delić-Šarac Izet Eminović Dragan Kovačević |
| author_facet | Đemo Subašić Jasenko Karamehić Farid Ljuca Faris Gavrankapetanović Marina Delić-Šarac Izet Eminović Dragan Kovačević |
| author_sort | Đemo Subašić |
| collection | DOAJ |
| description | Diagnosis and management of patients with SLE (Systemic Lupus Eritematosus), autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), involves specific diagnostic tests, such as IFA-AMA, IFA anti-dsDNA and immunoblotting for the detection of autoantibodies for specific autoantigens (mitochondria, dsDNA, M2, LKM-1, LC-1, SLA/LP). We established specific correlation between the detected autoantibodies and corresponding clinical findings.
The total of 813 serum specimens were probed with IFA-anti-dsDNA, 98 of which tested positive. We also performed dilution analysis to the end point for all the positive specimens. Numerous specimens were tested by IFA, AMA and immunoblotting.
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| first_indexed | 2024-04-24T23:31:25Z |
| format | Article |
| id | doaj.art-5c49f27ead204a3ea47c9bbae31a20b7 |
| institution | Directory Open Access Journal |
| issn | 2831-0896 2831-090X |
| language | English |
| last_indexed | 2024-04-24T23:31:25Z |
| publishDate | 2008-02-01 |
| publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
| record_format | Article |
| series | Biomolecules & Biomedicine |
| spelling | doaj.art-5c49f27ead204a3ea47c9bbae31a20b72024-03-15T14:38:20ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2008-02-018110.17305/bjbms.2008.3004596Correlation of Autoantibodies Presence Detected By IFA-anti-dsDNA, IFA-AMA and Immunoblotting with Corresponding Data in Clinical Management of Autoimmune DiseasesĐemo Subašić0Jasenko Karamehić1Farid Ljuca2Faris Gavrankapetanović3Marina Delić-Šarac4Izet Eminović5Dragan Kovačević6Institute of Clinical Immunology - University of Sarajevo Clinics CentreInstitute of Clinical Immunology - University of Sarajevo Clinics CentreDepartment of Physiology, Faculty of Medicine, University of TuzlaInstitute of Clinical Immunology - University of Sarajevo Clinics CentreInstitute of Clinical Immunology - University of Sarajevo Clinics CentreFaculty of Science, University of TuzlaInstitute of Clinical Immunology - University of Sarajevo Clinics CentreDiagnosis and management of patients with SLE (Systemic Lupus Eritematosus), autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), involves specific diagnostic tests, such as IFA-AMA, IFA anti-dsDNA and immunoblotting for the detection of autoantibodies for specific autoantigens (mitochondria, dsDNA, M2, LKM-1, LC-1, SLA/LP). We established specific correlation between the detected autoantibodies and corresponding clinical findings. The total of 813 serum specimens were probed with IFA-anti-dsDNA, 98 of which tested positive. We also performed dilution analysis to the end point for all the positive specimens. Numerous specimens were tested by IFA, AMA and immunoblotting. https://www.bjbms.org/ojs/index.php/bjbms/article/view/3004SLEAIHPBCIFAAMAanti-dsDNA |
| spellingShingle | Đemo Subašić Jasenko Karamehić Farid Ljuca Faris Gavrankapetanović Marina Delić-Šarac Izet Eminović Dragan Kovačević Correlation of Autoantibodies Presence Detected By IFA-anti-dsDNA, IFA-AMA and Immunoblotting with Corresponding Data in Clinical Management of Autoimmune Diseases Biomolecules & Biomedicine SLE AIH PBC IFA AMA anti-dsDNA |
| title | Correlation of Autoantibodies Presence Detected By IFA-anti-dsDNA, IFA-AMA and Immunoblotting with Corresponding Data in Clinical Management of Autoimmune Diseases |
| title_full | Correlation of Autoantibodies Presence Detected By IFA-anti-dsDNA, IFA-AMA and Immunoblotting with Corresponding Data in Clinical Management of Autoimmune Diseases |
| title_fullStr | Correlation of Autoantibodies Presence Detected By IFA-anti-dsDNA, IFA-AMA and Immunoblotting with Corresponding Data in Clinical Management of Autoimmune Diseases |
| title_full_unstemmed | Correlation of Autoantibodies Presence Detected By IFA-anti-dsDNA, IFA-AMA and Immunoblotting with Corresponding Data in Clinical Management of Autoimmune Diseases |
| title_short | Correlation of Autoantibodies Presence Detected By IFA-anti-dsDNA, IFA-AMA and Immunoblotting with Corresponding Data in Clinical Management of Autoimmune Diseases |
| title_sort | correlation of autoantibodies presence detected by ifa anti dsdna ifa ama and immunoblotting with corresponding data in clinical management of autoimmune diseases |
| topic | SLE AIH PBC IFA AMA anti-dsDNA |
| url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3004 |
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