The increasing of enamel calcium level after casein phosphopeptideamorphous calcium phosphate covering
<p><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Background: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: norm...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universitas Airlangga
2012-06-01
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| Series: | Dental Journal |
| Subjects: | |
| Online Access: | http://e-journal.unair.ac.id/index.php/MKG/article/view/830 |
| _version_ | 1819005099713757184 |
|---|---|
| author | Widyasri Prananingrum Puguh Bayu Prabowo |
| author_facet | Widyasri Prananingrum Puguh Bayu Prabowo |
| author_sort | Widyasri Prananingrum |
| collection | DOAJ |
| description | <p><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Background: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Caries process is characterized by the presence of demineralization. Demineralization is caused by organic acids as a </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>result of carbohydrate substrate fermentation. Remineralization is a natural repair process for non-cavitated lesions. Remineralization </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>occurs if there are Ca</em><span style="font-family: TribuneItalic; font-size: 7pt; color: #231f20; font-style: normal; font-variant: normal;"><em>2+ </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>and PO</em><span style="font-family: TribuneItalic; font-size: 7pt; color: #231f20; font-style: normal; font-variant: normal;"><em>43- </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>ions in sufficient quantities. Casein-amorphous calcium phosphate phosphopeptide (CPP-ACP) is a </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>paste material containing milk protein (casein), that actually contains minerals, such as calcium and phosphate. The casein ability to </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>stabilize calcium phosphate and enhance mineral solubility and bioavailability confers upon CPP potential to be biological delivery </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>vehicles for calcium and phosphate. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Purpose: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>The aim of this study was to determine the calcium levels in tooth enamel after being </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>covered with CPP-ACP 2 times a day for 3, 14 and 28 days. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Methods: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Sample were bovine incisors of 3 year old cows divided into </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>4 groups, namely group I as control group, group II, III and IV as treatment groups covered with CPP-ACP 2 times a day. All of </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>those teeth were then immersed in artificial saliva. Group II was immersed for 3 days, while group III was immersed for 14 days, and </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>group IV was immersed for 28 days. One drop of CPP-ACP was used to cover the entire labial surface of teeth. The measurement of </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>the calcium levels was then conducted by using titration method. All data were analyzed by One- Way ANOVA test with 5% degree of </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>confidence. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Results: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>The results showed significant difference of the calcium levels in tooth enamel of those groups after covered with </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>CPP-ACP 2 times a day for 3, 14 and 28 days (p = 0.001). There is also significant difference of the calcium levels in tooth enamel of </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>those treatment groups and the control group (p = 0.001). </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Conclusion: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>The calcium levels of tooth enamel are increased after covered </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>with CPP-ACP 2 times a day for 3, 14 and 28 days.</em></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></p><p><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 7pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 7pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Latar belakang: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Proses terjadinya karies gigi ditandai oleh adanya demineralisasi. Demineralisasi terjadi oleh asam organik </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>sebagai hasil fermentasi substrat karbohidrat oleh bakteri. Remineralisasi adalah proses perbaikan alami untuk lesi non cavitated. </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Remineralisasi terjadi jika terdapat ion Ca</em><span style="font-family: TribuneItalic; font-size: 7pt; color: #231f20; font-style: normal; font-variant: normal;"><em>2+ </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>dan PO</em><span style="font-family: TribuneItalic; font-size: 7pt; color: #231f20; font-style: normal; font-variant: normal;"><em>43- </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>dalam jumlah cukup. Casein phosphopeptide-amorphous calcium phosphate </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>(CPP-ACP) adalah bahan berbentuk pasta berisi suatu protein susu (kasein). Pada kasein terkandung mineral kalsium dan fosfat. </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Kemampuan kasein untuk menstabilkan kalsium fosfat dan meningkatkan kelarutan dan bioavailabilitas sehingga CPP memiliki </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>potensi menghantarkan kalsium dan fosfat. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Tujuan: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Tujuan penelitian ini untuk mengetahui kadar kalsium enamel setelah pengulasan </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>CPP-ACP pada permukaan enamel 2 kali sehari selama 3,14 dan 28 hari. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Metode: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Sampel adalah gigi insisif sapi, usia 3 tahun. </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Pada penelitian ini sampel (n = 24) dibagi menjadi 4 kelompok yaitu kelompok I sebagai kelompok kontrol, dan kelompok II, III, IV </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>sebagai kelompok perlakuan dengan pengulasan CPP-ACP 2 kali sehari. Semua kelompok direndam dalam saliva buatan. Kelompok </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>II direndam 3 hari, kelompok III direndam 14 hari, kelompok IV direndam 28 hari. Pengulasan CPP-ACP sejumlah 1 tetes diratakan </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>pada seluruh permukaan labial gigi. Pengukuran kadar kalsium dilakukan dengan metode titrasi. Semua data dianalisa dengan uji </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>One-Way ANOVA dengan taraf kemaknaan 5%. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Hasil: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Hasil penelitian menunjukkan perbedaan yang signifikan kadar kalsium enamel </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>gigi di antara kelompok (p = 0,001). Hasil penelitian menunjukkan perbedaan yang signifikan kadar kalsium gigi pada kelompok</em></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span> <span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>kontrol dan perlakuan antara lama waktu pengulasan 3, 14, dan 28 hari (p = 0,001). </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Kesimpulan: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Pengulasan CPP-ACP selama 3, </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>14 dan 28 hari mampu meningkatkan kadar kalsium pada enamel.</em></span></span></span></span><br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px;" /></span></span></span></span></span></span></span></span></span></span></span></span></span></span></p> |
| first_indexed | 2024-12-20T23:47:24Z |
| format | Article |
| id | doaj.art-5c4f56909be7458488edd242b85fa876 |
| institution | Directory Open Access Journal |
| issn | 1978-3728 2442-9740 |
| language | English |
| last_indexed | 2024-12-20T23:47:24Z |
| publishDate | 2012-06-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Dental Journal |
| spelling | doaj.art-5c4f56909be7458488edd242b85fa8762022-12-21T19:22:55ZengUniversitas AirlanggaDental Journal1978-37282442-97402012-06-01452939610.20473/j.djmkg.v45.i2.p93-96674The increasing of enamel calcium level after casein phosphopeptideamorphous calcium phosphate coveringWidyasri Prananingrum0Puguh Bayu Prabowo1Department of Dental Material Faculty of Dentistry, Universitas Hang TuahDepartment of Dental Material Faculty of Dentistry, Universitas Hang Tuah<p><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Background: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Caries process is characterized by the presence of demineralization. Demineralization is caused by organic acids as a </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>result of carbohydrate substrate fermentation. Remineralization is a natural repair process for non-cavitated lesions. Remineralization </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>occurs if there are Ca</em><span style="font-family: TribuneItalic; font-size: 7pt; color: #231f20; font-style: normal; font-variant: normal;"><em>2+ </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>and PO</em><span style="font-family: TribuneItalic; font-size: 7pt; color: #231f20; font-style: normal; font-variant: normal;"><em>43- </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>ions in sufficient quantities. Casein-amorphous calcium phosphate phosphopeptide (CPP-ACP) is a </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>paste material containing milk protein (casein), that actually contains minerals, such as calcium and phosphate. The casein ability to </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>stabilize calcium phosphate and enhance mineral solubility and bioavailability confers upon CPP potential to be biological delivery </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>vehicles for calcium and phosphate. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Purpose: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>The aim of this study was to determine the calcium levels in tooth enamel after being </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>covered with CPP-ACP 2 times a day for 3, 14 and 28 days. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Methods: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Sample were bovine incisors of 3 year old cows divided into </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>4 groups, namely group I as control group, group II, III and IV as treatment groups covered with CPP-ACP 2 times a day. All of </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>those teeth were then immersed in artificial saliva. Group II was immersed for 3 days, while group III was immersed for 14 days, and </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>group IV was immersed for 28 days. One drop of CPP-ACP was used to cover the entire labial surface of teeth. The measurement of </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>the calcium levels was then conducted by using titration method. All data were analyzed by One- Way ANOVA test with 5% degree of </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>confidence. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Results: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>The results showed significant difference of the calcium levels in tooth enamel of those groups after covered with </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>CPP-ACP 2 times a day for 3, 14 and 28 days (p = 0.001). There is also significant difference of the calcium levels in tooth enamel of </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>those treatment groups and the control group (p = 0.001). </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Conclusion: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>The calcium levels of tooth enamel are increased after covered </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>with CPP-ACP 2 times a day for 3, 14 and 28 days.</em></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></p><p><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 7pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 7pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Latar belakang: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Proses terjadinya karies gigi ditandai oleh adanya demineralisasi. Demineralisasi terjadi oleh asam organik </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>sebagai hasil fermentasi substrat karbohidrat oleh bakteri. Remineralisasi adalah proses perbaikan alami untuk lesi non cavitated. </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Remineralisasi terjadi jika terdapat ion Ca</em><span style="font-family: TribuneItalic; font-size: 7pt; color: #231f20; font-style: normal; font-variant: normal;"><em>2+ </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>dan PO</em><span style="font-family: TribuneItalic; font-size: 7pt; color: #231f20; font-style: normal; font-variant: normal;"><em>43- </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>dalam jumlah cukup. Casein phosphopeptide-amorphous calcium phosphate </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>(CPP-ACP) adalah bahan berbentuk pasta berisi suatu protein susu (kasein). Pada kasein terkandung mineral kalsium dan fosfat. </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Kemampuan kasein untuk menstabilkan kalsium fosfat dan meningkatkan kelarutan dan bioavailabilitas sehingga CPP memiliki </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>potensi menghantarkan kalsium dan fosfat. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Tujuan: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Tujuan penelitian ini untuk mengetahui kadar kalsium enamel setelah pengulasan </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>CPP-ACP pada permukaan enamel 2 kali sehari selama 3,14 dan 28 hari. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Metode: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Sampel adalah gigi insisif sapi, usia 3 tahun. </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Pada penelitian ini sampel (n = 24) dibagi menjadi 4 kelompok yaitu kelompok I sebagai kelompok kontrol, dan kelompok II, III, IV </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>sebagai kelompok perlakuan dengan pengulasan CPP-ACP 2 kali sehari. Semua kelompok direndam dalam saliva buatan. Kelompok </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>II direndam 3 hari, kelompok III direndam 14 hari, kelompok IV direndam 28 hari. Pengulasan CPP-ACP sejumlah 1 tetes diratakan </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>pada seluruh permukaan labial gigi. Pengukuran kadar kalsium dilakukan dengan metode titrasi. Semua data dianalisa dengan uji </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>One-Way ANOVA dengan taraf kemaknaan 5%. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Hasil: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Hasil penelitian menunjukkan perbedaan yang signifikan kadar kalsium enamel </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>gigi di antara kelompok (p = 0,001). Hasil penelitian menunjukkan perbedaan yang signifikan kadar kalsium gigi pada kelompok</em></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span> <span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>kontrol dan perlakuan antara lama waktu pengulasan 3, 14, dan 28 hari (p = 0,001). </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Kesimpulan: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Pengulasan CPP-ACP selama 3, </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>14 dan 28 hari mampu meningkatkan kadar kalsium pada enamel.</em></span></span></span></span><br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px;" /></span></span></span></span></span></span></span></span></span></span></span></span></span></span></p>http://e-journal.unair.ac.id/index.php/MKG/article/view/830Calciumenamelcasein phosphopeptide-amorphous calcium phosphateKalsiumenamelcasein phosphopeptide-amorphous calcium phosphate |
| spellingShingle | Widyasri Prananingrum Puguh Bayu Prabowo The increasing of enamel calcium level after casein phosphopeptideamorphous calcium phosphate covering Dental Journal Calcium enamel casein phosphopeptide-amorphous calcium phosphate Kalsium enamel casein phosphopeptide-amorphous calcium phosphate |
| title | The increasing of enamel calcium level after casein phosphopeptideamorphous calcium phosphate covering |
| title_full | The increasing of enamel calcium level after casein phosphopeptideamorphous calcium phosphate covering |
| title_fullStr | The increasing of enamel calcium level after casein phosphopeptideamorphous calcium phosphate covering |
| title_full_unstemmed | The increasing of enamel calcium level after casein phosphopeptideamorphous calcium phosphate covering |
| title_short | The increasing of enamel calcium level after casein phosphopeptideamorphous calcium phosphate covering |
| title_sort | increasing of enamel calcium level after casein phosphopeptideamorphous calcium phosphate covering |
| topic | Calcium enamel casein phosphopeptide-amorphous calcium phosphate Kalsium enamel casein phosphopeptide-amorphous calcium phosphate |
| url | http://e-journal.unair.ac.id/index.php/MKG/article/view/830 |
| work_keys_str_mv | AT widyasriprananingrum theincreasingofenamelcalciumlevelaftercaseinphosphopeptideamorphouscalciumphosphatecovering AT puguhbayuprabowo theincreasingofenamelcalciumlevelaftercaseinphosphopeptideamorphouscalciumphosphatecovering AT widyasriprananingrum increasingofenamelcalciumlevelaftercaseinphosphopeptideamorphouscalciumphosphatecovering AT puguhbayuprabowo increasingofenamelcalciumlevelaftercaseinphosphopeptideamorphouscalciumphosphatecovering |