Revealing the Metabolic Alterations during Biofilm Development of <i>Burkholderia cenocepacia</i> Based on Genome-Scale Metabolic Modeling

Revealing the Metabolic Alterations during Biofilm Development of <i>Burkholderia cenocepacia</i> Based on Genome-Scale Metabolic Modeling

<i>Burkholderia cenocepacia</i> is among the important pathogens isolated from cystic fibrosis (CF) patients. It has attracted considerable attention because of its capacity to evade host immune defenses during chronic infection. Advances in systems biology methodologies have led to the...

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Bibliographic Details
Main Authors: Ozlem Altay, Cheng Zhang, Hasan Turkez, Jens Nielsen, Mathias Uhlén, Adil Mardinoglu
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Metabolites
Subjects:
<i>Burkholderia cenocepacia</i>
biofilm
genome-scale metabolic models
synthetic lethality
transcriptomics
omics integration
Online Access:https://www.mdpi.com/2218-1989/11/4/221

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