Assessing progress in reducing the at-risk population after 13 years of the global programme to eliminate lymphatic filariasis.

In 1997, the World Health Assembly adopted Resolution 50.29, committing to the elimination of lymphatic filariasis (LF) as a public health problem, subsequently targeted for 2020. The initial estimates were that 1.2 billion people were at-risk for LF infection globally. Now, 13 years after the Globa...

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Main Authors: Pamela J Hooper, Brian K Chu, Alexei Mikhailov, Eric A Ottesen, Mark Bradley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4239000?pdf=render
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author Pamela J Hooper
Brian K Chu
Alexei Mikhailov
Eric A Ottesen
Mark Bradley
author_facet Pamela J Hooper
Brian K Chu
Alexei Mikhailov
Eric A Ottesen
Mark Bradley
author_sort Pamela J Hooper
collection DOAJ
description In 1997, the World Health Assembly adopted Resolution 50.29, committing to the elimination of lymphatic filariasis (LF) as a public health problem, subsequently targeted for 2020. The initial estimates were that 1.2 billion people were at-risk for LF infection globally. Now, 13 years after the Global Programme to Eliminate Lymphatic Filariasis (GPELF) began implementing mass drug administration (MDA) against LF in 2000-during which over 4.4 billion treatments have been distributed in 56 endemic countries-it is most appropriate to estimate the impact that the MDA has had on reducing the population at risk of LF.To assess GPELF progress in reducing the population at-risk for LF, we developed a model based on defining reductions in risk of infection among cohorts of treated populations following each round of MDA. The model estimates that the number of people currently at risk of infection decreased by 46% to 789 million through 2012.Important progress has been made in the global efforts to eliminate LF, but significant scale-up is required over the next 8 years to reach the 2020 elimination goal.
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spelling doaj.art-5c5adaeab2b84691ac61af2c34ef31242022-12-22T01:55:29ZengPublic Library of Science (PLoS)PLoS Neglected Tropical Diseases1935-27271935-27352014-11-01811e333310.1371/journal.pntd.0003333Assessing progress in reducing the at-risk population after 13 years of the global programme to eliminate lymphatic filariasis.Pamela J HooperBrian K ChuAlexei MikhailovEric A OttesenMark BradleyIn 1997, the World Health Assembly adopted Resolution 50.29, committing to the elimination of lymphatic filariasis (LF) as a public health problem, subsequently targeted for 2020. The initial estimates were that 1.2 billion people were at-risk for LF infection globally. Now, 13 years after the Global Programme to Eliminate Lymphatic Filariasis (GPELF) began implementing mass drug administration (MDA) against LF in 2000-during which over 4.4 billion treatments have been distributed in 56 endemic countries-it is most appropriate to estimate the impact that the MDA has had on reducing the population at risk of LF.To assess GPELF progress in reducing the population at-risk for LF, we developed a model based on defining reductions in risk of infection among cohorts of treated populations following each round of MDA. The model estimates that the number of people currently at risk of infection decreased by 46% to 789 million through 2012.Important progress has been made in the global efforts to eliminate LF, but significant scale-up is required over the next 8 years to reach the 2020 elimination goal.http://europepmc.org/articles/PMC4239000?pdf=render
spellingShingle Pamela J Hooper
Brian K Chu
Alexei Mikhailov
Eric A Ottesen
Mark Bradley
Assessing progress in reducing the at-risk population after 13 years of the global programme to eliminate lymphatic filariasis.
PLoS Neglected Tropical Diseases
title Assessing progress in reducing the at-risk population after 13 years of the global programme to eliminate lymphatic filariasis.
title_full Assessing progress in reducing the at-risk population after 13 years of the global programme to eliminate lymphatic filariasis.
title_fullStr Assessing progress in reducing the at-risk population after 13 years of the global programme to eliminate lymphatic filariasis.
title_full_unstemmed Assessing progress in reducing the at-risk population after 13 years of the global programme to eliminate lymphatic filariasis.
title_short Assessing progress in reducing the at-risk population after 13 years of the global programme to eliminate lymphatic filariasis.
title_sort assessing progress in reducing the at risk population after 13 years of the global programme to eliminate lymphatic filariasis
url http://europepmc.org/articles/PMC4239000?pdf=render
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