Radiotherapy of Conjunctival Melanoma: Role and Challenges of Brachytherapy, Photon-Beam and Protontherapy
Conjunctival melanoma is a rare neoplasia, whose therapeutic management is generally of ophthalmological relevance, through radical surgical resection. The high incidence of local relapses after surgery, has made it necessary to combine various types of adjuvant treatments, which in some cases take...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-12-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/10/24/9071 |
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| author | Corrado Spatola Rocco Luca Emanuele Liardo Roberto Milazzotto Luigi Raffaele Vincenzo Salamone Antonio Basile Pietro Valerio Foti Stefano Palmucci Giuseppe Antonio Pablo Cirrone Giacomo Cuttone Andrea Russo Teresio Avitabile Michele Reibaldi Antonio Longo Giuseppe Broggi Vincenza Bonfiglio Rosario Caltabiano Stefano Pergolizzi Floriana Arena |
| author_facet | Corrado Spatola Rocco Luca Emanuele Liardo Roberto Milazzotto Luigi Raffaele Vincenzo Salamone Antonio Basile Pietro Valerio Foti Stefano Palmucci Giuseppe Antonio Pablo Cirrone Giacomo Cuttone Andrea Russo Teresio Avitabile Michele Reibaldi Antonio Longo Giuseppe Broggi Vincenza Bonfiglio Rosario Caltabiano Stefano Pergolizzi Floriana Arena |
| author_sort | Corrado Spatola |
| collection | DOAJ |
| description | Conjunctival melanoma is a rare neoplasia, whose therapeutic management is generally of ophthalmological relevance, through radical surgical resection. The high incidence of local relapses after surgery, has made it necessary to combine various types of adjuvant treatments, which in some cases take on the role of radical treatments. Among these non-surgical treatments, those involving the application of ionizing radiation are becoming particularly important. In this review, we discuss the role of episcleral brachytherapy, external photon-beam radiotherapy, also made through stereotactic or radiosurgical modality, and of proton-beam radiotherapy. We try also to take stock of the benefits of the different irradiation modalities and the application difficulties of each. |
| first_indexed | 2024-03-10T13:57:06Z |
| format | Article |
| id | doaj.art-5c5b5cacfba9405cb55400837eb573b1 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T13:57:06Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-5c5b5cacfba9405cb55400837eb573b12023-11-21T01:29:26ZengMDPI AGApplied Sciences2076-34172020-12-011024907110.3390/app10249071Radiotherapy of Conjunctival Melanoma: Role and Challenges of Brachytherapy, Photon-Beam and ProtontherapyCorrado Spatola0Rocco Luca Emanuele Liardo1Roberto Milazzotto2Luigi Raffaele3Vincenzo Salamone4Antonio Basile5Pietro Valerio Foti6Stefano Palmucci7Giuseppe Antonio Pablo Cirrone8Giacomo Cuttone9Andrea Russo10Teresio Avitabile11Michele Reibaldi12Antonio Longo13Giuseppe Broggi14Vincenza Bonfiglio15Rosario Caltabiano16Stefano Pergolizzi17Floriana Arena18Dipartimento di Scienze Mediche, Chirurgiche e Tecnologie Avanzate “G.F. Ingrassia”, Università di Catania, 95125 Catania, ItalyUO Radiodiagnostica e Radioterapia Oncologica AOU Policlinico-S.Marco Catania, 95125 Catania, ItalyUO Radiodiagnostica e Radioterapia Oncologica AOU Policlinico-S.Marco Catania, 95125 Catania, ItalyUO Radiodiagnostica e Radioterapia Oncologica AOU Policlinico-S.Marco Catania, 95125 Catania, ItalyUO Radiodiagnostica e Radioterapia Oncologica AOU Policlinico-S.Marco Catania, 95125 Catania, ItalyDipartimento di Scienze Mediche, Chirurgiche e Tecnologie Avanzate “G.F. Ingrassia”, Università di Catania, 95125 Catania, ItalyDipartimento di Scienze Mediche, Chirurgiche e Tecnologie Avanzate “G.F. Ingrassia”, Università di Catania, 95125 Catania, ItalyDipartimento di Scienze Mediche, Chirurgiche e Tecnologie Avanzate “G.F. Ingrassia”, Università di Catania, 95125 Catania, ItalyIstituto Nazionale di Fisica Nucleare-LNS Catania, 95125 Catania, ItalyIstituto Nazionale di Fisica Nucleare-LNS Catania, 95125 Catania, ItalyDipartimento di Chirurgia Generale e Specialità Medico-Chirurgiche, Università di Catania, 95125 Catania, ItalyDipartimento di Chirurgia Generale e Specialità Medico-Chirurgiche, Università di Catania, 95125 Catania, ItalyDipartimento di Oftalmologia, Università di Torino, 10124 Torino, ItalyDipartimento di Chirurgia Generale e Specialità Medico-Chirurgiche, Università di Catania, 95125 Catania, ItalyDipartimento di Scienze Mediche, Chirurgiche e Tecnologie Avanzate “G.F. Ingrassia”, Università di Catania, 95125 Catania, ItalyDipartimento di Oftalmologia, Università di Palermo, 90133 Palermo, ItalyDipartimento di Scienze Mediche, Chirurgiche e Tecnologie Avanzate “G.F. Ingrassia”, Università di Catania, 95125 Catania, ItalyDepartment Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali, Università di Messina, 98100 Messina, ItalyDepartment Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali, Università di Messina, 98100 Messina, ItalyConjunctival melanoma is a rare neoplasia, whose therapeutic management is generally of ophthalmological relevance, through radical surgical resection. The high incidence of local relapses after surgery, has made it necessary to combine various types of adjuvant treatments, which in some cases take on the role of radical treatments. Among these non-surgical treatments, those involving the application of ionizing radiation are becoming particularly important. In this review, we discuss the role of episcleral brachytherapy, external photon-beam radiotherapy, also made through stereotactic or radiosurgical modality, and of proton-beam radiotherapy. We try also to take stock of the benefits of the different irradiation modalities and the application difficulties of each.https://www.mdpi.com/2076-3417/10/24/9071Conjunctival melanomaepiscleral brachytherapyproton-beam radiotherapy |
| spellingShingle | Corrado Spatola Rocco Luca Emanuele Liardo Roberto Milazzotto Luigi Raffaele Vincenzo Salamone Antonio Basile Pietro Valerio Foti Stefano Palmucci Giuseppe Antonio Pablo Cirrone Giacomo Cuttone Andrea Russo Teresio Avitabile Michele Reibaldi Antonio Longo Giuseppe Broggi Vincenza Bonfiglio Rosario Caltabiano Stefano Pergolizzi Floriana Arena Radiotherapy of Conjunctival Melanoma: Role and Challenges of Brachytherapy, Photon-Beam and Protontherapy Applied Sciences Conjunctival melanoma episcleral brachytherapy proton-beam radiotherapy |
| title | Radiotherapy of Conjunctival Melanoma: Role and Challenges of Brachytherapy, Photon-Beam and Protontherapy |
| title_full | Radiotherapy of Conjunctival Melanoma: Role and Challenges of Brachytherapy, Photon-Beam and Protontherapy |
| title_fullStr | Radiotherapy of Conjunctival Melanoma: Role and Challenges of Brachytherapy, Photon-Beam and Protontherapy |
| title_full_unstemmed | Radiotherapy of Conjunctival Melanoma: Role and Challenges of Brachytherapy, Photon-Beam and Protontherapy |
| title_short | Radiotherapy of Conjunctival Melanoma: Role and Challenges of Brachytherapy, Photon-Beam and Protontherapy |
| title_sort | radiotherapy of conjunctival melanoma role and challenges of brachytherapy photon beam and protontherapy |
| topic | Conjunctival melanoma episcleral brachytherapy proton-beam radiotherapy |
| url | https://www.mdpi.com/2076-3417/10/24/9071 |
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