A Short Review on Miniaturized Biosensors for the Detection of Nucleic Acid Biomarkers
Even today, most biomarker testing is executed in centralized, dedicated laboratories using bulky instruments, automated analyzers, and increased analysis time and expenses. The development of miniaturized, faster, low-cost microdevices is immensely anticipated for substituting for these conventiona...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Biosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6374/13/3/412 |
| _version_ | 1797613202397200384 |
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| author | Madhusudan B. Kulkarni Narasimha H. Ayachit Tejraj M. Aminabhavi |
| author_facet | Madhusudan B. Kulkarni Narasimha H. Ayachit Tejraj M. Aminabhavi |
| author_sort | Madhusudan B. Kulkarni |
| collection | DOAJ |
| description | Even today, most biomarker testing is executed in centralized, dedicated laboratories using bulky instruments, automated analyzers, and increased analysis time and expenses. The development of miniaturized, faster, low-cost microdevices is immensely anticipated for substituting for these conventional laboratory-oriented assays and transferring diagnostic results directly onto the patient’s smartphone using a cloud server. Pioneering biosensor-based approaches might make it possible to test biomarkers with reliability in a decentralized setting, but there are still a number of issues and restrictions that must be resolved before the development and use of several biosensors for the proper understanding of the measured biomarkers of numerous bioanalytes such as DNA, RNA, urine, and blood. One of the most promising processes to address some of the issues relating to the growing demand for susceptible, quick, and affordable analysis techniques in medical diagnostics is the creation of biosensors. This article critically discusses a short review of biosensors used for detecting nucleic acid biomarkers, and their use in biomedical prognostics will be addressed while considering several essential characteristics. |
| first_indexed | 2024-03-11T06:51:32Z |
| format | Article |
| id | doaj.art-5c5b5ede169d457ab74f6335991bd1d6 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-11T06:51:32Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-5c5b5ede169d457ab74f6335991bd1d62023-11-17T09:55:01ZengMDPI AGBiosensors2079-63742023-03-0113341210.3390/bios13030412A Short Review on Miniaturized Biosensors for the Detection of Nucleic Acid BiomarkersMadhusudan B. Kulkarni0Narasimha H. Ayachit1Tejraj M. Aminabhavi2School of Electronics and Communication Engineering, KLE Technological University, Vidyanagar, Hubballi 580023, Karnataka, IndiaSchool of Advanced Sciences, KLE Technological University, Hubballi 580031, Karnataka, IndiaSchool of Advanced Sciences, KLE Technological University, Hubballi 580031, Karnataka, IndiaEven today, most biomarker testing is executed in centralized, dedicated laboratories using bulky instruments, automated analyzers, and increased analysis time and expenses. The development of miniaturized, faster, low-cost microdevices is immensely anticipated for substituting for these conventional laboratory-oriented assays and transferring diagnostic results directly onto the patient’s smartphone using a cloud server. Pioneering biosensor-based approaches might make it possible to test biomarkers with reliability in a decentralized setting, but there are still a number of issues and restrictions that must be resolved before the development and use of several biosensors for the proper understanding of the measured biomarkers of numerous bioanalytes such as DNA, RNA, urine, and blood. One of the most promising processes to address some of the issues relating to the growing demand for susceptible, quick, and affordable analysis techniques in medical diagnostics is the creation of biosensors. This article critically discusses a short review of biosensors used for detecting nucleic acid biomarkers, and their use in biomedical prognostics will be addressed while considering several essential characteristics.https://www.mdpi.com/2079-6374/13/3/412biosensorsdeoxyribonucleic acid (DNA)biomarkermicrofluidicspoint-of-care-testing (POCT) |
| spellingShingle | Madhusudan B. Kulkarni Narasimha H. Ayachit Tejraj M. Aminabhavi A Short Review on Miniaturized Biosensors for the Detection of Nucleic Acid Biomarkers Biosensors biosensors deoxyribonucleic acid (DNA) biomarker microfluidics point-of-care-testing (POCT) |
| title | A Short Review on Miniaturized Biosensors for the Detection of Nucleic Acid Biomarkers |
| title_full | A Short Review on Miniaturized Biosensors for the Detection of Nucleic Acid Biomarkers |
| title_fullStr | A Short Review on Miniaturized Biosensors for the Detection of Nucleic Acid Biomarkers |
| title_full_unstemmed | A Short Review on Miniaturized Biosensors for the Detection of Nucleic Acid Biomarkers |
| title_short | A Short Review on Miniaturized Biosensors for the Detection of Nucleic Acid Biomarkers |
| title_sort | short review on miniaturized biosensors for the detection of nucleic acid biomarkers |
| topic | biosensors deoxyribonucleic acid (DNA) biomarker microfluidics point-of-care-testing (POCT) |
| url | https://www.mdpi.com/2079-6374/13/3/412 |
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