Parity and the risk of diabetes mellitus among Chinese women: a cross-sectional evidence from the Tongji-Dongfeng cohort study.
Little is known about the long-term health impact of pregnancy on women. The objective of this study was to examine the association between parity and the risk of diabetes among a population of Chinese women.A total of 14,196 women (aged ≥ 45 years) from the Dongfeng-Tongji Cohort study who had expe...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4126778?pdf=render |
| _version_ | 1819104233259008000 |
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| author | Yaohua Tian Lijun Shen Jing Wu Weihong Chen Jing Yuan Handong Yang Youjie Wang Yuan Liang Tangchun Wu |
| author_facet | Yaohua Tian Lijun Shen Jing Wu Weihong Chen Jing Yuan Handong Yang Youjie Wang Yuan Liang Tangchun Wu |
| author_sort | Yaohua Tian |
| collection | DOAJ |
| description | Little is known about the long-term health impact of pregnancy on women. The objective of this study was to examine the association between parity and the risk of diabetes among a population of Chinese women.A total of 14,196 women (aged ≥ 45 years) from the Dongfeng-Tongji Cohort study who had experienced at least one live birth completed baseline questionnaires, medical examinations, and provided baseline blood samples. Participants were categorized into four groups according to parity (one, two, three, or four or more live births). Logistic regression models were used to investigate the association between parity and the risk of diabetes after controlling potential confounders.The prevalence of diabetes in the study population was 18.0% (2,552/14,196). Fasting plasma glucose levels increased with the increasing number of live births (P<0.001) and parity had a positive graded association with diabetes without adjustment for any covariates (P for trend <0.001). After adjusting for potential confounders, women who had had two, three, and four or more live births had 1.35 times (95% CI, 1.20-1.52), 1.59 times (95% CI, 1.39-1.82) and 1.44 times (95% CI, 1.21-1.71), respectively, higher risk of diabetes compared with women who had had one live birth.Multiparity was associated with increasing risk of diabetes in this population of Chinese women. These findings suggested that multiparity may be a risk factor for the development of diabetes among Chinese women. Future studies are needed to examine the physiological changes during pregnancy for risk of diabetes in later life. |
| first_indexed | 2024-12-22T02:03:06Z |
| format | Article |
| id | doaj.art-5c5e8d2c3bbe4604ad0d2b0d9e7bfabe |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-22T02:03:06Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-5c5e8d2c3bbe4604ad0d2b0d9e7bfabe2022-12-21T18:42:36ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0198e10481010.1371/journal.pone.0104810Parity and the risk of diabetes mellitus among Chinese women: a cross-sectional evidence from the Tongji-Dongfeng cohort study.Yaohua TianLijun ShenJing WuWeihong ChenJing YuanHandong YangYoujie WangYuan LiangTangchun WuLittle is known about the long-term health impact of pregnancy on women. The objective of this study was to examine the association between parity and the risk of diabetes among a population of Chinese women.A total of 14,196 women (aged ≥ 45 years) from the Dongfeng-Tongji Cohort study who had experienced at least one live birth completed baseline questionnaires, medical examinations, and provided baseline blood samples. Participants were categorized into four groups according to parity (one, two, three, or four or more live births). Logistic regression models were used to investigate the association between parity and the risk of diabetes after controlling potential confounders.The prevalence of diabetes in the study population was 18.0% (2,552/14,196). Fasting plasma glucose levels increased with the increasing number of live births (P<0.001) and parity had a positive graded association with diabetes without adjustment for any covariates (P for trend <0.001). After adjusting for potential confounders, women who had had two, three, and four or more live births had 1.35 times (95% CI, 1.20-1.52), 1.59 times (95% CI, 1.39-1.82) and 1.44 times (95% CI, 1.21-1.71), respectively, higher risk of diabetes compared with women who had had one live birth.Multiparity was associated with increasing risk of diabetes in this population of Chinese women. These findings suggested that multiparity may be a risk factor for the development of diabetes among Chinese women. Future studies are needed to examine the physiological changes during pregnancy for risk of diabetes in later life.http://europepmc.org/articles/PMC4126778?pdf=render |
| spellingShingle | Yaohua Tian Lijun Shen Jing Wu Weihong Chen Jing Yuan Handong Yang Youjie Wang Yuan Liang Tangchun Wu Parity and the risk of diabetes mellitus among Chinese women: a cross-sectional evidence from the Tongji-Dongfeng cohort study. PLoS ONE |
| title | Parity and the risk of diabetes mellitus among Chinese women: a cross-sectional evidence from the Tongji-Dongfeng cohort study. |
| title_full | Parity and the risk of diabetes mellitus among Chinese women: a cross-sectional evidence from the Tongji-Dongfeng cohort study. |
| title_fullStr | Parity and the risk of diabetes mellitus among Chinese women: a cross-sectional evidence from the Tongji-Dongfeng cohort study. |
| title_full_unstemmed | Parity and the risk of diabetes mellitus among Chinese women: a cross-sectional evidence from the Tongji-Dongfeng cohort study. |
| title_short | Parity and the risk of diabetes mellitus among Chinese women: a cross-sectional evidence from the Tongji-Dongfeng cohort study. |
| title_sort | parity and the risk of diabetes mellitus among chinese women a cross sectional evidence from the tongji dongfeng cohort study |
| url | http://europepmc.org/articles/PMC4126778?pdf=render |
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