Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators
Purpose: To investigate the underlying diseases, and complaints of patients upon admission, isolated microorganisms from tracheal aspirate (TA) samples and their resistance to antibiotics in patients followed up with a home mechanic ventilator (HMV). Materials and Methods: Between January 1, 2020...
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Format: | Article |
Language: | English |
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Kirsehir Ahi Evran University
2023-12-01
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Series: | Ahi Evran Medical Journal |
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Online Access: | https://dergipark.org.tr/tr/download/article-file/2723389 |
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author | Esra AKYÜZ ÖZKAN Demet GÜR VURAL |
author_facet | Esra AKYÜZ ÖZKAN Demet GÜR VURAL |
author_sort | Esra AKYÜZ ÖZKAN |
collection | DOAJ |
description | Purpose: To investigate the underlying diseases, and complaints of patients upon admission, isolated microorganisms from tracheal aspirate (TA) samples and their resistance to antibiotics in patients followed up with a home mechanic ventilator (HMV).
Materials and Methods: Between January 1, 2020 and January 1, 2021, TA cultures, identification of bacteria and their antibiotic susceptibilities were evaluated by VITEK 2 (bioMeriux, France) automated identification system. The patients' age, gender, underlying diseases, duration of home ventilator use, complaints, and laboratory data were reviewed.
Results: Of the 91 prediagnosed ventilator-associated pneumonia (VAP) patients, 72 (79%) were male and mean age was 91.64 ± 64.07 months. The most common reason for referral was fever and dyspnea and 43.76% of the patients were diagnosed with cerebral palsy/epilepsy and 10.4% with syndromes.
Of the samples; 12 (13.3%) were defined as Gram-positive and 79 (86.7%) as Gram-negative. Pseudomonas aeruginosa was detected in 44 (48.4%) samples, Serratia marcescens in 9 (9.9%), Klebsiella spp. in 8 (8.8%) and Staphylococcus aureus was in 12 (13.3%) samples. Carbapenem resistance was 18.75% for Pseudomonas aeruginosa, 16% for Klebsiella spp, 12.5 for Escherichia coli and 12% for Acinetobacter baumannii.
Conclusion: TA culture should be taken from patients with HMV who were admitted with signs of infection such as fever and respiratory distress and treatment should be arranged according to the result. It was observed that the TA culture antibiotic resistance rates of the patients with HMV were lower than the TA cultures sent from the patients hospitalized in the intensive care unit in the literature. |
first_indexed | 2024-03-08T18:58:52Z |
format | Article |
id | doaj.art-5c618e2896e14d85af095b8edb73b59b |
institution | Directory Open Access Journal |
issn | 2619-9203 |
language | English |
last_indexed | 2024-03-08T18:58:52Z |
publishDate | 2023-12-01 |
publisher | Kirsehir Ahi Evran University |
record_format | Article |
series | Ahi Evran Medical Journal |
spelling | doaj.art-5c618e2896e14d85af095b8edb73b59b2023-12-28T08:06:37ZengKirsehir Ahi Evran UniversityAhi Evran Medical Journal2619-92032023-12-017334034510.46332/aemj.1192753Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical VentilatorsEsra AKYÜZ ÖZKAN0https://orcid.org/0000-0001-9412-8010Demet GÜR VURAL1https://orcid.org/0000-0003-2974-6589ONDOKUZ MAYIS ÜNİVERSİTESİONDOKUZ MAYIS ÜNİVERSİTESİPurpose: To investigate the underlying diseases, and complaints of patients upon admission, isolated microorganisms from tracheal aspirate (TA) samples and their resistance to antibiotics in patients followed up with a home mechanic ventilator (HMV). Materials and Methods: Between January 1, 2020 and January 1, 2021, TA cultures, identification of bacteria and their antibiotic susceptibilities were evaluated by VITEK 2 (bioMeriux, France) automated identification system. The patients' age, gender, underlying diseases, duration of home ventilator use, complaints, and laboratory data were reviewed. Results: Of the 91 prediagnosed ventilator-associated pneumonia (VAP) patients, 72 (79%) were male and mean age was 91.64 ± 64.07 months. The most common reason for referral was fever and dyspnea and 43.76% of the patients were diagnosed with cerebral palsy/epilepsy and 10.4% with syndromes. Of the samples; 12 (13.3%) were defined as Gram-positive and 79 (86.7%) as Gram-negative. Pseudomonas aeruginosa was detected in 44 (48.4%) samples, Serratia marcescens in 9 (9.9%), Klebsiella spp. in 8 (8.8%) and Staphylococcus aureus was in 12 (13.3%) samples. Carbapenem resistance was 18.75% for Pseudomonas aeruginosa, 16% for Klebsiella spp, 12.5 for Escherichia coli and 12% for Acinetobacter baumannii. Conclusion: TA culture should be taken from patients with HMV who were admitted with signs of infection such as fever and respiratory distress and treatment should be arranged according to the result. It was observed that the TA culture antibiotic resistance rates of the patients with HMV were lower than the TA cultures sent from the patients hospitalized in the intensive care unit in the literature.https://dergipark.org.tr/tr/download/article-file/2723389antibiotic resistancetracheal aspiratehome mechanical ventilationpediatrics |
spellingShingle | Esra AKYÜZ ÖZKAN Demet GÜR VURAL Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators Ahi Evran Medical Journal antibiotic resistance tracheal aspirate home mechanical ventilation pediatrics |
title | Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators |
title_full | Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators |
title_fullStr | Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators |
title_full_unstemmed | Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators |
title_short | Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators |
title_sort | evaluation of tracheal aspirate cultures of patients followed with home mechanical ventilators |
topic | antibiotic resistance tracheal aspirate home mechanical ventilation pediatrics |
url | https://dergipark.org.tr/tr/download/article-file/2723389 |
work_keys_str_mv | AT esraakyuzozkan evaluationoftrachealaspirateculturesofpatientsfollowedwithhomemechanicalventilators AT demetgurvural evaluationoftrachealaspirateculturesofpatientsfollowedwithhomemechanicalventilators |