Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators

Purpose: To investigate the underlying diseases, and complaints of patients upon admission, isolated microorganisms from tracheal aspirate (TA) samples and their resistance to antibiotics in patients followed up with a home mechanic ventilator (HMV). Materials and Methods: Between January 1, 2020...

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Main Authors: Esra AKYÜZ ÖZKAN, Demet GÜR VURAL
Format: Article
Language:English
Published: Kirsehir Ahi Evran University 2023-12-01
Series:Ahi Evran Medical Journal
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/2723389
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author Esra AKYÜZ ÖZKAN
Demet GÜR VURAL
author_facet Esra AKYÜZ ÖZKAN
Demet GÜR VURAL
author_sort Esra AKYÜZ ÖZKAN
collection DOAJ
description Purpose: To investigate the underlying diseases, and complaints of patients upon admission, isolated microorganisms from tracheal aspirate (TA) samples and their resistance to antibiotics in patients followed up with a home mechanic ventilator (HMV). Materials and Methods: Between January 1, 2020 and January 1, 2021, TA cultures, identification of bacteria and their antibiotic susceptibilities were evaluated by VITEK 2 (bioMeriux, France) automated identification system. The patients' age, gender, underlying diseases, duration of home ventilator use, complaints, and laboratory data were reviewed. Results: Of the 91 prediagnosed ventilator-associated pneumonia (VAP) patients, 72 (79%) were male and mean age was 91.64 ± 64.07 months. The most common reason for referral was fever and dyspnea and 43.76% of the patients were diagnosed with cerebral palsy/epilepsy and 10.4% with syndromes. Of the samples; 12 (13.3%) were defined as Gram-positive and 79 (86.7%) as Gram-negative. Pseudomonas aeruginosa was detected in 44 (48.4%) samples, Serratia marcescens in 9 (9.9%), Klebsiella spp. in 8 (8.8%) and Staphylococcus aureus was in 12 (13.3%) samples. Carbapenem resistance was 18.75% for Pseudomonas aeruginosa, 16% for Klebsiella spp, 12.5 for Escherichia coli and 12% for Acinetobacter baumannii. Conclusion: TA culture should be taken from patients with HMV who were admitted with signs of infection such as fever and respiratory distress and treatment should be arranged according to the result. It was observed that the TA culture antibiotic resistance rates of the patients with HMV were lower than the TA cultures sent from the patients hospitalized in the intensive care unit in the literature.
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spelling doaj.art-5c618e2896e14d85af095b8edb73b59b2023-12-28T08:06:37ZengKirsehir Ahi Evran UniversityAhi Evran Medical Journal2619-92032023-12-017334034510.46332/aemj.1192753Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical VentilatorsEsra AKYÜZ ÖZKAN0https://orcid.org/0000-0001-9412-8010Demet GÜR VURAL1https://orcid.org/0000-0003-2974-6589ONDOKUZ MAYIS ÜNİVERSİTESİONDOKUZ MAYIS ÜNİVERSİTESİPurpose: To investigate the underlying diseases, and complaints of patients upon admission, isolated microorganisms from tracheal aspirate (TA) samples and their resistance to antibiotics in patients followed up with a home mechanic ventilator (HMV). Materials and Methods: Between January 1, 2020 and January 1, 2021, TA cultures, identification of bacteria and their antibiotic susceptibilities were evaluated by VITEK 2 (bioMeriux, France) automated identification system. The patients' age, gender, underlying diseases, duration of home ventilator use, complaints, and laboratory data were reviewed. Results: Of the 91 prediagnosed ventilator-associated pneumonia (VAP) patients, 72 (79%) were male and mean age was 91.64 ± 64.07 months. The most common reason for referral was fever and dyspnea and 43.76% of the patients were diagnosed with cerebral palsy/epilepsy and 10.4% with syndromes. Of the samples; 12 (13.3%) were defined as Gram-positive and 79 (86.7%) as Gram-negative. Pseudomonas aeruginosa was detected in 44 (48.4%) samples, Serratia marcescens in 9 (9.9%), Klebsiella spp. in 8 (8.8%) and Staphylococcus aureus was in 12 (13.3%) samples. Carbapenem resistance was 18.75% for Pseudomonas aeruginosa, 16% for Klebsiella spp, 12.5 for Escherichia coli and 12% for Acinetobacter baumannii. Conclusion: TA culture should be taken from patients with HMV who were admitted with signs of infection such as fever and respiratory distress and treatment should be arranged according to the result. It was observed that the TA culture antibiotic resistance rates of the patients with HMV were lower than the TA cultures sent from the patients hospitalized in the intensive care unit in the literature.https://dergipark.org.tr/tr/download/article-file/2723389antibiotic resistancetracheal aspiratehome mechanical ventilationpediatrics
spellingShingle Esra AKYÜZ ÖZKAN
Demet GÜR VURAL
Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators
Ahi Evran Medical Journal
antibiotic resistance
tracheal aspirate
home mechanical ventilation
pediatrics
title Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators
title_full Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators
title_fullStr Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators
title_full_unstemmed Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators
title_short Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators
title_sort evaluation of tracheal aspirate cultures of patients followed with home mechanical ventilators
topic antibiotic resistance
tracheal aspirate
home mechanical ventilation
pediatrics
url https://dergipark.org.tr/tr/download/article-file/2723389
work_keys_str_mv AT esraakyuzozkan evaluationoftrachealaspirateculturesofpatientsfollowedwithhomemechanicalventilators
AT demetgurvural evaluationoftrachealaspirateculturesofpatientsfollowedwithhomemechanicalventilators