Hypertonic seawater solution with brown algae extract Ascophillum nodosum in the treatment of acute rhinosinusitis
The article presents modern approaches to the modulation of cellular factors of innate immunity, oxidative stress factors when using a hypertonic seawater solution with Ascophillum nodosum brown algae extract (NaCl 15 g/l) in patients with acute rhinosinusitis.Characteristics of the children and res...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Ltd. “The National Academy of Pediatric Science and Innovation”
2020-05-01
|
| Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
| Subjects: | |
| Online Access: | https://www.ped-perinatology.ru/jour/article/view/1121 |
| _version_ | 1797875168093143040 |
|---|---|
| author | О. A. Gizinger |
| author_facet | О. A. Gizinger |
| author_sort | О. A. Gizinger |
| collection | DOAJ |
| description | The article presents modern approaches to the modulation of cellular factors of innate immunity, oxidative stress factors when using a hypertonic seawater solution with Ascophillum nodosum brown algae extract (NaCl 15 g/l) in patients with acute rhinosinusitis.Characteristics of the children and research methods. The authors examined 102 children aged from 5 to 8 years, with a history of more than 5 episodes of acute rhinosinusitis per year. We evaluated the quantitative and qualitative composition of neutrophilic granulocytes in washes from the mucous membrane of the nasal cavity, the production of reactive oxygen species (ROS) by neutrophilic granulocytes, the content of lipid peroxidation products, enzymes of the antioxidant system – superoxide dismutase and catalase in nasal washes.Results. The authors found that the nasal spray of a hypertonic seawater solution with Ascophillum nodosum brown algae extract helps to normalize clinical picture, reduce number of relapses, restore functional and metabolic status of neutrophils of the nasal mucosa surface, restore balance of lipid peroxidation factors, antioxidant sustem enzymes – superoxide dismutase and catalase. |
| first_indexed | 2024-04-10T01:42:15Z |
| format | Article |
| id | doaj.art-5c68e2b3849e4a9cb0b8fc46c557b45e |
| institution | Directory Open Access Journal |
| issn | 1027-4065 2500-2228 |
| language | Russian |
| last_indexed | 2024-04-10T01:42:15Z |
| publishDate | 2020-05-01 |
| publisher | Ltd. “The National Academy of Pediatric Science and Innovation” |
| record_format | Article |
| series | Rossijskij Vestnik Perinatologii i Pediatrii |
| spelling | doaj.art-5c68e2b3849e4a9cb0b8fc46c557b45e2023-03-13T09:12:48ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282020-05-0165213314010.21508/1027-4065-2020-65-2-133-140880Hypertonic seawater solution with brown algae extract Ascophillum nodosum in the treatment of acute rhinosinusitisО. A. Gizinger0Медицинский институт ФГАОУ ВО «Российский университет дружбы народов»The article presents modern approaches to the modulation of cellular factors of innate immunity, oxidative stress factors when using a hypertonic seawater solution with Ascophillum nodosum brown algae extract (NaCl 15 g/l) in patients with acute rhinosinusitis.Characteristics of the children and research methods. The authors examined 102 children aged from 5 to 8 years, with a history of more than 5 episodes of acute rhinosinusitis per year. We evaluated the quantitative and qualitative composition of neutrophilic granulocytes in washes from the mucous membrane of the nasal cavity, the production of reactive oxygen species (ROS) by neutrophilic granulocytes, the content of lipid peroxidation products, enzymes of the antioxidant system – superoxide dismutase and catalase in nasal washes.Results. The authors found that the nasal spray of a hypertonic seawater solution with Ascophillum nodosum brown algae extract helps to normalize clinical picture, reduce number of relapses, restore functional and metabolic status of neutrophils of the nasal mucosa surface, restore balance of lipid peroxidation factors, antioxidant sustem enzymes – superoxide dismutase and catalase.https://www.ped-perinatology.ru/jour/article/view/1121дети, риносинусит, врожденный иммунитет, оксидативный стресс, гипертонический раствор морской воды, экстракт бурых водорослей ascophillum nodosum |
| spellingShingle | О. A. Gizinger Hypertonic seawater solution with brown algae extract Ascophillum nodosum in the treatment of acute rhinosinusitis Rossijskij Vestnik Perinatologii i Pediatrii дети, риносинусит, врожденный иммунитет, оксидативный стресс, гипертонический раствор морской воды, экстракт бурых водорослей ascophillum nodosum |
| title | Hypertonic seawater solution with brown algae extract Ascophillum nodosum in the treatment of acute rhinosinusitis |
| title_full | Hypertonic seawater solution with brown algae extract Ascophillum nodosum in the treatment of acute rhinosinusitis |
| title_fullStr | Hypertonic seawater solution with brown algae extract Ascophillum nodosum in the treatment of acute rhinosinusitis |
| title_full_unstemmed | Hypertonic seawater solution with brown algae extract Ascophillum nodosum in the treatment of acute rhinosinusitis |
| title_short | Hypertonic seawater solution with brown algae extract Ascophillum nodosum in the treatment of acute rhinosinusitis |
| title_sort | hypertonic seawater solution with brown algae extract ascophillum nodosum in the treatment of acute rhinosinusitis |
| topic | дети, риносинусит, врожденный иммунитет, оксидативный стресс, гипертонический раствор морской воды, экстракт бурых водорослей ascophillum nodosum |
| url | https://www.ped-perinatology.ru/jour/article/view/1121 |
| work_keys_str_mv | AT oagizinger hypertonicseawatersolutionwithbrownalgaeextractascophillumnodosuminthetreatmentofacuterhinosinusitis |