Increased plasma cholesterol esterification by LCAT reduces diet-induced atherosclerosis in SR-BI knockout mice[S]

Increased plasma cholesterol esterification by LCAT reduces diet-induced atherosclerosis in SR-BI knockout mice[S]

LCAT, a plasma enzyme that esterifies cholesterol, has been proposed to play an antiatherogenic role, but animal and epidemiologic studies have yielded conflicting results. To gain insight into LCAT and the role of free cholesterol (FC) in atherosclerosis, we examined the effect of LCAT over- and un...

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Bibliographic Details
Main Authors:	Seth G. Thacker, Xavier Rousset, Safiya Esmail, Abdalrahman Zarzour, Xueting Jin, Heidi L. Collins, Maureen Sampson, John Stonik, Stephen Demosky, Daniela A. Malide, Lita Freeman, Boris L. Vaisman, Howard S. Kruth, Steven J. Adelman, Alan T. Remaley
Format:	Article
Language:	English
Published:	Elsevier 2015-07-01
Series:	Journal of Lipid Research
Subjects:	lecithin:cholesterol acyltransferase scavenger receptor class B member I knockout
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520355486

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